Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lauren S Godwin"'
Autor:
Claire J Cairney, Lauren S Godwin, Alan E Bilsland, Sharon Burns, Katrina H Stevenson, Lynn McGarry, John Revie, Jon D Moore, Ceri M Wiggins, Rebecca S Collinson, Clare Mudd, Elpida Tsonou, Mahito Sadaie, Dorothy C Bennett, Masashi Narita, Christopher J Torrance, W Nicol Keith
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006942 (2017)
Senescence is a universal barrier to immortalisation and tumorigenesis. As such, interest in the use of senescence-induction in a therapeutic context has been gaining momentum in the past few years; however, senescence and immortalisation remain unde
Externí odkaz:
https://doaj.org/article/9c37fdc4728e4b2584673b3d2d9b5b8b
The genome is associated with several structures inside cell nuclei, in order to regulate its activity and anchor it in specific locations. These structures are collectively known as the nucleoskeleton and include the nuclear lamina, the nucleoli, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212c1727e2cc104e52e18b3e5f569f90
http://bura.brunel.ac.uk/handle/2438/21931
http://bura.brunel.ac.uk/handle/2438/21931
Autor:
Mehmet U. Bikkul, Joanna M. Bridger, Craig S. Clements, Lauren S. Godwin, Ian R. Kill, Martin W. Goldberg
Publikováno v:
Biogerontology
Biogerontology, 2018, Vol.19(6), pp.579-602 [Peer Reviewed Journal]
Biogerontology, 2018, Vol.19(6), pp.579-602 [Peer Reviewed Journal]
Hutchinson–Gilford progeria syndrome (HGPS) is a rare and fatal premature ageing disease in children. HGPS is one of several progeroid syndromes caused by mutations in the LMNA gene encoding the nuclear structural proteins lamins A and C. In classi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429d5898315377b4d14f0feadec93d82
https://pubmed.ncbi.nlm.nih.gov/29907918
https://pubmed.ncbi.nlm.nih.gov/29907918
Autor:
Mai Hassan Ahmed, Ural Bikkul, Joanna M. Bridger, Helen A. Foster, Lauren S. Godwin, Craig S. Clements
Publikováno v:
Methods in Molecular Biology ISBN: 9781493935284
The genome has a special relationship with the nuclear envelope in cells. Much of the genome is anchored at the nuclear periphery, tethered by chromatin binding proteins such nuclear lamins and other integral membrane proteins. Even though there are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8f5b90a0134f718753a80ffbd51f40
https://doi.org/10.1007/978-1-4939-3530-7_24
https://doi.org/10.1007/978-1-4939-3530-7_24
Autor:
Mahito Sadaie, Christian Dillon, Masashi Narita, Andrew R. J. Young, Claire J. Cairney, Lauren S. Godwin, Christopher J. Torrance, Dorothy C. Bennett, W. Nicol Keith
Publikováno v:
Molecular Biology of the Cell
Compound screening for altered nuclear phenotypes identifies several promiscuous kinase inhibitors that trigger progression of senescence during a polyploid G1. Their common target is AURKB. More-specific inhibition of AURKB phenocopies these compoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177765c54f4bb0ab31cb9f10b51ce226
https://eprints.gla.ac.uk/110612/1/110612.pdf
https://eprints.gla.ac.uk/110612/1/110612.pdf
Autor:
Jaskaren S. Kohli, Elena V. Sviderskaya, W. Nicol Keith, Joanna T. Castle, Claire J. Cairney, Philip S. Goff, Dorothy C. Bennett, Lauren S. Godwin
Publikováno v:
Current Protocols in Cell Biology
Located in the basal epidermis and hair follicles, melanocytes of the integument are responsible for its coloration through production of melanin pigments. Melanin is produced in lysosomal-like organelles called melanosomes. In humans, this skin pigm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753d8659f2b73066453436b24e562cb9
https://doi.org/10.1002/0471143030.cb0108s63
https://doi.org/10.1002/0471143030.cb0108s63
Autor:
Joanna M, Bridger, Halime D, Arican-Gotkas, Helen A, Foster, Lauren S, Godwin, Amanda, Harvey, Ian R, Kill, Matty, Knight, Ishita S, Mehta, Mai Hassan, Ahmed
Publikováno v:
Advances in experimental medicine and biology. 773
The genomes of a wide range of different organisms are non-randomly organized within interphase nuclei. Chromosomes and genes can be moved rapidly, with direction, to new non-random locations within nuclei upon a stimulus such as a signal to initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d470b7587710dcb6204d2af96b18faf
https://pubmed.ncbi.nlm.nih.gov/24563352
https://pubmed.ncbi.nlm.nih.gov/24563352
Autor:
Lauren S. Godwin, Ishita S. Mehta, Amanda J. Harvey, Joanna M. Bridger, Matty Knight, Ian R. Kill, Halime D. Arican-Gotkas, Mai Hassan Ahmed, Helen A. Foster
Publikováno v:
Cancer Biology and the Nuclear Envelope ISBN: 9781489980311
The genomes of a wide range of different organisms are non-randomly organized within interphase nuclei. Chromosomes and genes can be moved rapidly, with direction, to new non-random locations within nuclei upon a stimulus such as a signal to initiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303c15854ebe731ea0a6ed22844bbff8
https://doi.org/10.1007/978-1-4899-8032-8_28
https://doi.org/10.1007/978-1-4899-8032-8_28
Autor:
Joanna M. Bridger, Halime D. Arican-Gotkas, Helen A. Foster, Lauren S. Godwin, Amanda Harvey, Ian R. Kill, Matty Knight, Ishita S. Mehta, Mai Hassan Ahmed
Publikováno v:
Cancer Biology and the Nuclear Envelope ISBN: 9781489980311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27fd473859ae1ec173867513350e34fb
https://doi.org/10.1007/978-1-4899-8032-8_12
https://doi.org/10.1007/978-1-4899-8032-8_12