Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lauren S, Mohan"'
Autor:
Victor L. Quan, Bin Zhang, Katherine Shi, Daniel Kim, Erin M. Garfield, Pedram Gerami, Elsy V. Compres, Elnaz Panah, Lauren S. Mohan, Ayesha U. Khan
Publikováno v:
Journal of the American Academy of Dermatology. 83:1028-1034
Background Atypical network encompasses several patterns. Few studies assess the sensitivity, specificity, and positive and negative predictive values of network subtypes. Objective We assessed the diagnostic value of atypical network subtypes and th
Autor:
Lauren S. Mohan, Lacey Kruse, Kevin P. White, Katherine Shi, Annette Wagner, Timothy Taxter, Bin Zhang, Yongzhan Zhang, Victor L. Quan, Nike Beaubier, Lihua Zou, Pedram Gerami
Publikováno v:
Journal of Investigative Dermatology. 140:1599-1608
The newest World Health Organization classification of skin tumors suggests the elimination of cases with BRAF and NRAS mutations from the categories of Spitz tumors (ST) and Spitz melanoma (SM). The objective of this study is to better characterize
Autor:
Pedram Gerami, June K. Robinson, Lauren S. Mohan, Pedram Yazdan, Victor L. Quan, Erin M. Garfield, Daniel Kim, Katherine Shi, Bin Zhang, Ayesha U. Khan, Elsy V. Compres, Elnaz Panah, Kara E. Walton
Publikováno v:
Archives of Dermatological Research. 313:101-108
Histopathologic assessment of melanocytic neoplasms is the current gold standard of diagnosis. However, there are well recognized limitations including inter-observer diagnostic discordance. This study aimed to determine if integrating dermoscopy wit
Autor:
Nike Beaubier, Kevin P. White, Lauren S. Mohan, Timothy Taxter, Bin Zhang, Victor L. Quan, Katherine Shi, Daniel Kim, Maria Cristina Isales, Pedram Yazdan, Yongzhan Zhang, Pedram Gerami, Ayesha U. Khan, Elsy V. Compres, Elnaz Panah
Publikováno v:
The American Journal of Dermatopathology. 42:641-647
Background Some melanomas closely resemble pigmented spindle cell nevi (PSCN) of Reed histologically. The distinction of these entities is important for clinical management. A recent study showed most PSCN (78%) are fusion-driven, commonly involving
Publikováno v:
Journal of Cutaneous Pathology. 46:878-887
Recent advances in next generation sequencing (NGS) have allowed for efficient whole transcriptome sequencing, leading to the identification of important kinase fusions as the primary driver in some melanocytic neoplasms. These fusions typically occu
Autor:
Lauren S. Mohan, Pedram Yazdan, Timothy Taxter, Bin Zhang, Maria Cristina Isales, Nike Beaubier, Victor L. Quan, Nicoleta C. Arva, Kevin P. White, Pedram Gerami, Katherine Shi, Erin M. Garfield
Publikováno v:
American Journal of Surgical Pathology. 43:480-488
Pigmented epithelioid melanocytoma (PEM) is considered an intermediate grade melanocytic lesion that is histologically indistinguishable from epithelioid blue nevi associated with Carney complex. PEM are characterized by an intradermal population of
Autor:
Kevin P. White, Elnaz Panah, Maria Cristina Isales, Nike Beaubier, Lauren S. Mohan, Victor L. Quan, Timothy Taxter, Bin Zhang, Pedram Gerami, Katherine Shi
Publikováno v:
American Journal of Surgical Pathology. 43:538-548
Recent studies have described kinase fusions as the most common initiating genomic events in Spitzoid neoplasms. Each rearrangement generates a chimeric protein with constitutive activation of the tyrosine kinase domain, resulting in the development
Autor:
Katherine, Shi, Elsy, Compres, Kara E, Walton, Lauren S, Mohan, Bin, Zhang, Elnaz, Panah, Victor L, Quan, Erin M, Garfield, Ayesha U, Khan, Daniel, Kim, Pedram, Yazdan, June K, Robinson, Pedram, Gerami
Publikováno v:
Archives of dermatological research. 313(2)
Histopathologic assessment of melanocytic neoplasms is the current gold standard of diagnosis. However, there are well recognized limitations including inter-observer diagnostic discordance. This study aimed to determine if integrating dermoscopy wit
Autor:
Yongzhan Zhang, Timothy Taxter, Bin Zhang, Victor L. Quan, Katherine Shi, Betty Y. Kong, Maria Cristina Isales, Lihua Zou, Kevin P. White, Lauren S. Mohan, Elnaz Panah, Catherine Igartua, Pedram Gerami, Nike Beaubier
Publikováno v:
Journal of the American Academy of Dermatology.
Background Compared to sun-exposed melanomas, less is known regarding the pathogenesis of sun-protected melanomas. Sun-protected melanomas share many epidemiologic factors but their genetic heterogeneity is not well studied. Objective We investigated
Publikováno v:
The Lancet. Childadolescent health. 3(9)
Paediatric melanoma is rare and challenging to diagnose. The three subtypes are Spitzoid melanoma, melanoma arising in a congenital melanocytic nevus, and conventional (also known as adult-type) melanoma. Spitzoid melanomas have characteristic histop