Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lauren R. Pepper"'
Autor:
Heather Cohen, Yasmin Hashambhoy-Ramsay, Lauren R. Pepper, Jeffrey Y. Smith, Margaret Willer, Kevin Guay, Vikki Spaulding, Kristin O'Malley, Monica Gostissa, Abha Dhaneshwar, Edward C. Stack, Alessandro Mora, Donald R. Shaffer
Publikováno v:
Cancer Research. 79:5007-5007
Introduction: Jounce has generated cell type-specific gene signatures as a means of probing The Cancer Genome Atlas and other large datasets to identify targets that may be important immune checkpoints. Using a tumor-associated macrophage (TAM) gene
Isolation of L I domain mutants mediating firm cell adhesion using a novel flow-based sorting method
Autor:
Gregory P. Robbins, Daniel A. Hammer, Ranganath Parthasarathy, Eric T. Boder, Lauren R. Pepper, Nicholas N. Dang
Publikováno v:
Protein Engineering Design and Selection. 26:515-521
The inserted (I) domain of αLβ2 integrin (LFA-1) contains the entire binding site of the molecule. It mediates both rolling and firm adhesion of leukocytes at sites of inflammation depending on the activation state of the integrin. The affinity cha
Publikováno v:
Langmuir. 27:13701-13712
Elucidation of the relationship between targeting molecule binding properties and the adhesive behavior of therapeutic or diagnostic nanocarriers would aid in the design of optimized vectors and lead to improved efficacy. We measured the adhesion of
Autor:
Vanessa Zuzarte-Luis, Lauren R. Pepper, Jon Clardy, Olaf Wiest, Clary B. Clish, Ralph Mazitschek, Paul Schimmel, Dyann F. Wirth, Tracy Keller, Sofia A. Santos, William J. Sullivan, Maria M. Mota, Huihao Zhou, Amanda K. Lukens, Ulf Ribacke, Susan Lindquist, Selina Bopp, Jonathan D. Herman, Guillermina Estiu, Malcolm Whitman, Vishal Patel, Emily R. Derbyshire, Joseph F. Cortese, Kevin Galinsky
Publikováno v:
PMC
Copyright © 2015, American Association for the Advancement of Science.
The emergence of drug resistance is a major limitation of current antimalarials. The discovery of new druggable targets and pathways including those that are critical for mu
The emergence of drug resistance is a major limitation of current antimalarials. The discovery of new druggable targets and pathways including those that are critical for mu
Publikováno v:
Combinatorial chemistryhigh throughput screening. 11(2)
Yeast surface display has become an increasingly popular tool for protein engineering and library screening applications. Recent advances have greatly expanded the capability of yeast surface display, and are highlighted by cell-based selections, epi
Publikováno v:
Langmuir; Nov2011, Vol. 27 Issue 22, p13701-13712, 12p