Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lauren R. Brinster"'
Autor:
Marie Reine Haddad, Eun-Young Choi, Patricia M. Zerfas, Ling Yi, Diego Martinelli, Patricia Sullivan, David S. Goldstein, Jose A. Centeno, Lauren R. Brinster, Martina Ralle, Stephen G. Kaler
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 165-178 (2018)
Menkes disease is a lethal neurodegenerative disorder of copper metabolism caused by mutations in an evolutionarily conserved copper transporter, ATP7A. Based on our prior clinical and animal studies, we seek to develop a therapeutic approach suitabl
Externí odkaz:
https://doaj.org/article/a4cc1ab740b44d4f9ac2ad5537b6c26f
Publikováno v:
EBioMedicine, Vol 23, Iss C, Pp 125-135 (2017)
Despite its transport by glucose transporters (GLUTs) in vitro, it is unknown whether dehydroascorbic acid (oxidized vitamin C, DHA) has any in vivo function. To investigate, we created a chemical transport knockout model using the vitamin C analog 6
Externí odkaz:
https://doaj.org/article/179e1352b0ae4e648624d43630fc7dde
Autor:
Adela M. Francis-Malavé, Santiago Martínez González, Caren Pichardo, Torri D. Wilson, Luis G. Rivera-García, Lauren R. Brinster, Yarimar Carrasquillo
Publikováno v:
Pain. 164:197-215
Previous studies have reported sex differences in patients with irritable bowel syndrome and inflammatory bowel disease, including differences in visceral pain perception. Despite this, sex differences in behavioral manifestations of visceral pain an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a0b4abdad1a85eab15845d40940202
https://doi.org/10.1097/j.pain.0000000000002683
https://doi.org/10.1097/j.pain.0000000000002683
Autor:
Ross A. McDevitt, Lauren R. Brinster, Rafael de Cabo, Luigi Ferrucci, Giovanni E Finesso, Andrea Di Francesco, Theresa Meade, Kathy A Perdue, Roshni Roy
Publikováno v:
J Gerontol A Biol Sci Med Sci
Age-dependent differences in methylation at specific cytosine–guanine (CpG) sites have been used in “epigenetic clock” formulas to predict age. Deviations of epigenetic age from chronological age are informative of health status and are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0bad37134bd37f248e727e7f3c7018
https://doi.org/10.1093/gerona/glab328
https://doi.org/10.1093/gerona/glab328
Autor:
Adela M. Francis-Malave, Santiago Martinez Gonzalez, Caren Pichardo, Torri D. Wilson, Luis G. Rivera, Lauren R. Brinster, Yarimar Carrasquillo
Previous studies have reported sex differences in irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) patients, including differences in visceral pain perception. Despite this, sex differences in behavioral manifestations of visceral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbbd00dcd42194cc158e5e339e38f838
https://doi.org/10.1101/2022.01.11.475721
https://doi.org/10.1101/2022.01.11.475721
Autor:
Zhijie Wu, Jisoo Kim, Sabrina Solorzano, Gladys Gonzalez-Matias, Xingmin Feng, Neal S. Young, Kaylind Batey, Lauren R. Brinster, Jichun Chen
Publikováno v:
Exp Hematol
Exposure of young C57BL/6 (B6) mice to two courses of busulfan (BSF) injections or two rounds of sublethal total body irradiation (TBI) induced significant damage to the function of hematopoietic stem and progenitor cells (HSPCs). Fifteen weeks follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077ebb0ea98592edc61531c8ac6af810
https://europepmc.org/articles/PMC8724411/
https://europepmc.org/articles/PMC8724411/
Autor:
Kim M. Keppler-Noreuil, Lauren R Brinster, Cecilia Rivas, Neil J. Sebire, Marjorie J. Lindhurst, Gene Elliot, Hannah C. Kondolf, Jasmine Shwetar, Miranda R. Yourick, Pamela L. Schwartzberg, Henoke Shiferaw, Leslie G. Biesecker, Lisa Garrett, Julio Gomez-Rodriguez, Stephen M. Hewitt
Publikováno v:
Hum Mol Genet
Proteus syndrome is a mosaic, progressive overgrowth disorder caused by a somatic activating variant c.49G > A p.(E17K) in AKT1. The presentation in affected individuals is variable, with a diversity of tissues demonstrating abnormalities. Common man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec8edba2247c78da59dd40668ec885a
https://doi.org/10.1093/hmg/ddz116
https://doi.org/10.1093/hmg/ddz116
Autor:
Adela M. Francis Malave, Santiago Martinez Gonzalez, Caren Pichardo, Torri D. Wilson, Luis G. Rivera, Lauren R. Brinster, Yarimar Carrasquillo
Publikováno v:
The Journal of Pain. 23:57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0d8057e8ee475e29bba67b7fa9306c5
https://doi.org/10.1016/j.jpain.2022.03.215
https://doi.org/10.1016/j.jpain.2022.03.215
Publikováno v:
Comparative Medicine. 68:353-359
Unexpected mortality occurred in a group of 12 NOD.Cg-Prkdc(scid)Il2rg(tm1Wjl)/SzJ (NSG) and 12 NOD.Cg-Rag1(tm1Mom) Il2rg(tm1Wjl)/SzJ (NRG) immunodeficient mice. At 10 d after routine bone marrow–liver–thymus humanization surgery, 9 mice were fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9366c09d3dfffd642d93db11f0454acc
https://doi.org/10.30802/aalas-cm-17-000104
https://doi.org/10.30802/aalas-cm-17-000104
Autor:
Stephen G. Kaler, Patricia M. Zerfas, Lauren R. Brinster, Ling Yi, Jose A. Centeno, Martina Ralle, Diego Martinelli, Marie Reine Haddad, Eun-Young Choi, Patricia Sullivan, David S. Goldstein
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 165-178 (2018)
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 165-178 (2018)
Menkes disease is a lethal neurodegenerative disorder of copper metabolism caused by mutations in an evolutionarily conserved copper transporter, ATP7A. Based on our prior clinical and animal studies, we seek to develop a therapeutic approach suitabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d58010869ef6f76404bb3686b7f5be1
https://doi.org/10.1016/j.omtm.2018.07.002
https://doi.org/10.1016/j.omtm.2018.07.002