Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lauren R. Bringman"'
Autor:
Barbara J. Bailey, Karen E. Pollok, Clark D. Wells, David L. Waning, Eva Tonsing-Carter, Robert E. Minto, Jann N. Sarkaria, Harlan E. Shannon, Jixin Ding, Wenjing Cai, Shanbao Cai, Aaron Cohen-Gadol, M. Reza Saadatzadeh, David R. Jones, Lindsey D. Mayo, Lawrence M. Gelbert, Eric C. Long, T. Zachary Gunter, Kevin R. Gordon, Jacob A. Eitel, Lauren R. Bringman, Haiyan Wang, Stephanie E. Sen, Taxiarchis M. Georgiadis, Mary E. Murray
Publikováno v:
Journal of Neurosurgery. 126:446-459
OBJECTIVE Improvement in treatment outcome for patients with glioblastoma multiforme (GBM) requires a multifaceted approach due to dysregulation of numerous signaling pathways. The murine double minute 2 (MDM2) protein may fulfill this requirement be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bda7ff87c095cb134b6b75ea82aad9
https://doi.org/10.3171/2016.1.jns152513
https://doi.org/10.3171/2016.1.jns152513
Publikováno v:
The American Biology Teacher. 75:559-565
We developed an interactive laboratory that allows students to identify and grade tissue samples from human breast biopsies, using techniques similar to those used by actual pathologists. This unique lab develops a practical and intellectual understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0eea9afa3a5d66358eeb44dcafef132c
https://doi.org/10.1525/abt.2013.75.8.7
https://doi.org/10.1525/abt.2013.75.8.7
Autor:
Hyun-Suk Lim, Jacob J. Adler, Ross Cocklin, Misook Oh, Mark G. Goebl, William P. Ranahan, Brigitte L. Heller, Lauren R. Bringman, Clark D. Wells, Robert J. Ingham
Publikováno v:
Journal of Biological Chemistry. 288:15181-15193
The adaptor protein Amot130 scaffolds components of the Hippo pathway to promote the inhibition of cell growth. This study describes how Amot130 through binding and activating the ubiquitin ligase AIP4/Itch achieves these effects. AIP4 is found to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a8dc5d3dc5ec9d0e50ff916e75d322
https://doi.org/10.1074/jbc.m112.446534
https://doi.org/10.1074/jbc.m112.446534
Autor:
Lauren R. Bringman, George D. Bennett
Publikováno v:
Synthetic Communications. 41:898-902
Four novel bicyclo[4.3.0]non-3-ene-7,9-diones have been synthesized in moderate to good yields through a solventless Diels–Alder cycloaddition method and characterized. Atom economies after purification ranged from 21% to 32%, and E factors ranged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::863d80af9304d003a930227926a7494d
https://doi.org/10.1080/00397911003707097
https://doi.org/10.1080/00397911003707097
Publikováno v:
Journal of Chemical Crystallography. 40:76-79
The title compounds, C10H12O4 and C12H14O5, were prepared as part of an ongoing study to explore the practical aspects of solventless reaction methods. As confirmed by the crystal structures, treatment of maleic anhydride with (2E,4E)-hexa-2,4-dien-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d32386a28dd7a221e4f4b85b62ede36
https://doi.org/10.1007/s10870-009-9647-4
https://doi.org/10.1007/s10870-009-9647-4
Autor:
Jacob J. Adler, Derrick E. Johnson, Michael Conwell, Brigitte L. Heller, Lauren R. Bringman, William P. Ranahan, Andy Hudmon, Clark D. Wells, Yang Sun
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(43)
Large tumor suppressor (LATS)1/2 protein kinases transmit Hippo signaling in response to intercellular contacts and serum levels to limit cell growth via the inhibition of Yes-associated protein (YAP). Here low serum and high LATS1 activity are found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ad983679ac0752fe5aa63e38b6e5c7
https://pubmed.ncbi.nlm.nih.gov/24101513
https://pubmed.ncbi.nlm.nih.gov/24101513