Výsledky vyhledávání - "Lauren R Walling"

A 3’ UTR-derived small RNA connecting nitrogen and carbon metabolism in enteric bacteria

Autor: Lauren R Walling, Andrew B Kouse, Svetlana A Shabalina, Hongen Zhang, Gisela Storz

Publikováno v: Nucleic Acids Res

Increasing numbers of small, regulatory RNAs (sRNAs) corresponding to 3’ untranslated regions (UTR) are being discovered in bacteria. One such sRNA, denoted GlnZ, corresponds to the 3’ UTR of the Escherichia coli glnA mRNA encoding glutamine synt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb97bf82f4155fca6bd92e7b1814651
https://doi.org/10.1101/2022.04.01.486790

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Toxins targeting transfer RNAs: Translation inhibition by bacterial toxin–antitoxin systems

Autor: Lauren R. Walling, J. Scott Butler

Publikováno v: WIREs RNA. 10

Prokaryotic toxin-antitoxin (TA) systems are composed of a protein toxin and its cognate antitoxin. These systems are abundant in bacteria and archaea and play an important role in growth regulation. During favorable growth conditions, the antitoxin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c316d075b2b24ea6401528efd10174
https://doi.org/10.1002/wrna.1506

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Homologous VapC Toxins Inhibit Translation and Cell Growth by Sequence-Specific Cleavage of tRNA fMet

Autor: Lauren R. Walling, J. Scott Butler

Publikováno v: Journal of Bacteriology. 200

Type II toxin-antitoxin (TA) systems play a critical role in the establishment and maintenance of bacterial dormancy. They are composed of a protein toxin and its cognate protein antitoxin. They function to regulate growth under conditions of stress,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d761200a6a7425e1af48e2cec927c8
https://doi.org/10.1128/jb.00582-17

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Structural Determinants for Antitoxin Identity and Insulation of Cross Talk between Homologous Toxin-Antitoxin Systems

Autor: J. Scott Butler, Lauren R. Walling

Publikováno v: Journal of bacteriology. 198(24)

Toxin-antitoxin (TA) systems are ubiquitous in bacteria and archaea, where they play a pivotal role in the establishment and maintenance of dormancy. Under normal growth conditions, the antitoxin neutralizes the toxin. However, under conditions of st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be968648683edf1a6459a1e9142ee63a
https://pubmed.ncbi.nlm.nih.gov/27672196

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