Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lauren R Kett"'
Autor:
Ippolita Cantuti-Castelvetri, Ledia F Hernandez, Christine E Keller-McGandy, Lauren R Kett, Alex Landy, Zane R Hollingsworth, Esen Saka, Jill R Crittenden, Eduardo A Nillni, Anne B Young, David G Standaert, Ann M Graybiel
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13861 (2010)
Dyskinesias associated with involuntary movements and painful muscle contractions are a common and severe complication of standard levodopa (L-DOPA, L-3,4-dihydroxyphenylalanine) therapy for Parkinson's disease. Pathologic neuroplasticity leading to
Externí odkaz:
https://doaj.org/article/dc2baa9047584c208c2b171d8395cf7b
Autor:
Alexis Roy, Vickie Y. Jo, Jeffrey P. Guenette, Lauren R. Kett, Edison Miyawaki, Meabh O'Hare, Rachel A. Caplan, Shamik Bhattacharyya, Liangge Hsu, Lillian W Dattilo
Publikováno v:
Case Reports in Neurology
Case Reports in Neurology, Vol 12, Iss 2, Pp 247-254 (2020)
Case Reports in Neurology, Vol 12, Iss 2, Pp 247-254 (2020)
We report two cases of biopsy-corroborated “fibrosing inflammatory pseudotumor” to illustrate that the entity, rarely described in the neurological literature, should be included in the differential diagnosis of either a cranial mononeuropathy or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65af3d9c140241b6dce04007ef3b09c
http://europepmc.org/articles/PMC7383149
http://europepmc.org/articles/PMC7383149
Autor:
Sarah E. Conway, Pavan A. Vaswani, Joshua A. Budhu, Lauren R. Kett, Silviya H.M. Eaton, Wei Wang, Michael P. Bowley, Sashank Prasad
Publikováno v:
Neurology. 98(23)
Appropriate parental leave policies remain an unmet need in graduate medical education. Although legal and institutional guidelines allow for policies that support parental leave, there are many challenges and perceived barriers to consider in develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4a2b7f24344dcff5f4305006cdd11e8
https://pubmed.ncbi.nlm.nih.gov/35418451
https://pubmed.ncbi.nlm.nih.gov/35418451
Publikováno v:
Neurohospitalist
A 63-year-old right-handed man was admitted to our hospital after sustaining a traumatic right-sided subdural hematoma, subarachnoid hemorrhage, and temporal lobe hemorrhagic contusion. He was managed non-operatively and discharged without any neurol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb829681cc4a2e4a20e5fec222579a9
https://europepmc.org/articles/PMC8182391/
https://europepmc.org/articles/PMC8182391/
Autor:
William T. Dauer, Lauren R. Kett
Publikováno v:
Movement Disorders. 31:1433-1443
Increasingly, genetic, cell biological, and in vivo work emphasizes the role of the endolysosomal system dysfunction in Parkinson's disease pathogenesis. Yet many questions remain about the mechanisms by which primary endolysosomal dysfunction causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0bf5004d9693deced0ee2c05b812ea1
https://doi.org/10.1002/mds.26797
https://doi.org/10.1002/mds.26797
Autor:
Megan M. Bernath, Bowen Zhou, Javier Blesa, Serge Przedborski, Vernice Jackson-Lewis, William T. Dauer, Robin B. Chan, Inmaculada Tasset, Barbara Stiller, Gilbert Di Paolo, Lauren R. Kett, Ana Maria Cuervo
Publikováno v:
The Journal of Neuroscience. 35:5724-5742
Accumulating evidence from genetic and biochemical studies implicates dysfunction of the autophagic-lysosomal pathway as a key feature in the pathogenesis of Parkinson's disease (PD). Most studies have focused on accumulation of neurotoxic α-synucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b0c490b1bec705fa8630944e3e21db
https://doi.org/10.1523/jneurosci.0632-14.2015
https://doi.org/10.1523/jneurosci.0632-14.2015
Autor:
Lauren R, Kett, William T, Dauer
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society. 31(10)
Increasingly, genetic, cell biological, and in vivo work emphasizes the role of the endolysosomal system dysfunction in Parkinson's disease pathogenesis. Yet many questions remain about the mechanisms by which primary endolysosomal dysfunction causes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::baf5cebb0fff3a338841fd3ffc07cabe
https://pubmed.ncbi.nlm.nih.gov/27619535
https://pubmed.ncbi.nlm.nih.gov/27619535
Autor:
Daniela Boassa, Cherry Cheng Ying Ho, Lauren R. Kett, Hardy J. Rideout, Junru Hu, William T. Dauer, Masako Terada, Mark H. Ellisman
Publikováno v:
Human Molecular Genetics. 21:890-899
Dominant missense mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic causes of Parkinson disease (PD) and genome-wide association studies identify LRRK2 sequence variants as risk factors for sporadic PD. Intact kinase funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7744efca8d43bec76821042d7691b94d
https://doi.org/10.1093/hmg/ddr526
https://doi.org/10.1093/hmg/ddr526
Autor:
Li-Huei Tsai, Anthone W. Dunah, Allison A. Curley, D. Cristopher Bragg, Ramses Ayala, Jay L. Duffner, Lauren R. Kett, Anne B. Young, Lianna R. Orlando
Publikováno v:
Journal of Neurochemistry. 110:557-569
Phosphorylation of neurotransmitter receptors can modify their activity and regulate neuronal excitability. Cyclin-dependent kinase 5 (cdk5) is a proline-directed serine/threonine kinase involved not only in neuronal development, but also in synaptic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df136284b27062e966074ce0aa2c8592
https://doi.org/10.1111/j.1471-4159.2009.06139.x
https://doi.org/10.1111/j.1471-4159.2009.06139.x
Autor:
Lauren R. Kett, William T. Dauer
Publikováno v:
Cold Spring Harbor perspectives in medicine. 2(3)
Parkinson’s disease (PD) was long believed to result from environmental insults, with little or no role for genetic factors. This notion began to change in 1997 with the discovery of PD-causing mutations in the SNCA gene that encodes α-synuclein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3fbded72d7f08941fb25086785e95b
https://pubmed.ncbi.nlm.nih.gov/22393539
https://pubmed.ncbi.nlm.nih.gov/22393539