Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lauren R Abbott"'
Publikováno v:
Molecules, Vol 25, Iss 23, p 5662 (2020)
Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times. They have enjoyed over 30 years of clinical usage and become essential tools in the armoury of clinical treatments. FQs target the bacterial enzymes DNA gyrase
Externí odkaz:
https://doaj.org/article/2974e7bcf3454ec993d26d40a63b7d7d
Autor:
Kyle M. Orritt, Lipeng Feng, Juliette F. Newell, Jack N. Sutton, Scott Grossman, Thomas Germe, Lauren R. Abbott, Holly L. Jackson, Benjamin K. L. Bury, Anthony Maxwell, Martin J. McPhillie, Colin W. G. Fishwick
Publikováno v:
RSC Medicinal Chemistry. 13:831-839
A computational design, make and test strategy was used to identify antibacterial inhibitors of bacterial DNA gyrase and topoisomerase IV, proposed to bind at a novel allosteric site.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519fd7fc93ae6a9798c16c90eec91cb2
https://doi.org/10.1039/d2md00049k
https://doi.org/10.1039/d2md00049k
Publikováno v:
Molecules, Vol 25, Iss 5662, p 5662 (2020)
Molecules
Molecules
Fluoroquinolones (FQs) are arguably among the most successful antibiotics of recent times. They have enjoyed over 30 years of clinical usage and become essential tools in the armoury of clinical treatments. FQs target the bacterial enzymes DNA gyrase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a3056480a1380b9fc85fd6d86a419b
https://www.mdpi.com/1420-3049/25/23/5662
https://www.mdpi.com/1420-3049/25/23/5662