Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lauren Podmore"'
Autor:
Lauren Podmore, Yekaterina Poloz, Catherine Iorio, Samar Mouaaz, Kevin Nixon, Petr Smirnov, Brianna McDonnell, Sonya Lam, Bowen Zhang, Pirashaanthy Tharmapalan, Soumili Sarkar, Foram Vyas, Marguerite Ennis, Ryan Dowling, Vuk Stambolic
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113251- (2023)
Summary: Breast cancer (BC) prognosis and outcome are adversely affected by obesity. Hyperinsulinemia, common in the obese state, is associated with higher risk of death and recurrence in BC. Up to 80% of BCs overexpress the insulin receptor (INSR),
Externí odkaz:
https://doaj.org/article/0a98286f0bdb4289aa404e39db449838
Nek kinases are involved in regulating several different elements of the centrosomal cycle, primary cilia function, and DNA damage responses. Unlike the other members of the Nek family, which are serine-threonine kinases, Nek10 preferentially targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b1f8227ed8ab1703725417e9b7cf6b
https://doi.org/10.1101/2022.12.23.521717
https://doi.org/10.1101/2022.12.23.521717
Autor:
Lauren Podmore, Yekaterina Poloz, Samar Mouaaz, Marguerite Ennis, Petr Smirnov, Sonya Lam, Ryan Dowling, Vuk Stambolic
Breast cancer (BC) prognosis and outcome are adversely affected by increased body weight, obesity and the obesity-associated type 2 diabetes. Hyperinsulinemia, which is commonly seen as part of metabolic reprograming in the obese state, has been asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73a3e1f97d2d7824850cd86ba3409955
https://doi.org/10.1101/2022.05.06.490906
https://doi.org/10.1101/2022.05.06.490906
Autor:
Richard Marcellus, Osamu Muto, Donna L. Senger, Rima Al-awar, Constanza Rioseco, Ahmed Aman, David L. Kaplan, Michael D. Blough, Marco A. Marra, Lauren Podmore, Greg J. Cairncross, Xueqing Lun, Steven J.M. Jones, David Uehling, Natalie Grinshtein, Stephen M. Robbins, Yaoqing Shen, Jake Lever
Publikováno v:
Oncotarget
Glioblastoma (GBM) is the most lethal and aggressive adult brain tumor, requiring the development of efficacious therapeutics. Towards this goal, we screened five genetically distinct patient-derived brain-tumor initiating cell lines (BTIC) with a un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3be14bdf7d9517ee953d8fec1df6663
https://eprints.gla.ac.uk/242669/1/242669.pdf
https://eprints.gla.ac.uk/242669/1/242669.pdf
Autor:
Natalie Grinshtein, Donna L. Senger, Gregory Cairncross, Marco A. Marra, Rima Al-awar, Constanza Rioseco, Steve Jones, Osamu Muto, David R. Kaplan, David Uehling, Richard Marcellus, Xueqing Lun, Steve Robbins, Lauren Podmore, Ahmed Aman
Publikováno v:
Neuro-Oncology. 18:vi75-vi76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c93cec0e410afc930e9f8765fd0259c0
https://doi.org/10.1093/neuonc/now212.317
https://doi.org/10.1093/neuonc/now212.317
Autor:
Lauren Podmore, Josie Ursini-Siegel, Nicole Beauchemin, Laura Forrest, Jacqueline R. Ha, Julie Livingstone, Ryuhjin Ahn, Jennifer F. Knight, Valerie Sabourin, Jesse Hudson, Michael Hallett, Rachel La Selva, Morag Park
Publikováno v:
Molecular and cellular biology. 34(19)
Breast cancers are stratified into distinct subtypes, which influence therapeutic responsiveness and patient outcome. Patients with luminal breast cancers are often associated with a better prognosis relative to that with other subtypes. However, sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a9944c08644e2597ce92b3279dfb9d
https://pubmed.ncbi.nlm.nih.gov/25071152
https://pubmed.ncbi.nlm.nih.gov/25071152