Výsledky vyhledávání - "Lauren Pejza"

Abstract 4259: PT199, a next generation anti-CD73 mAb that inhibits both membrane-bound and soluble CD73 activity to completion without 'hook effect'

Autor: Haiqun (John) Jia, Jack Li, Fen Pei, Lorraine Greenwood, Lauren Pejza, Yan Long, Kelan Chen, Jessica Perer, Ming Wang, Hui Zou

Publikováno v: Cancer Research. 82:4259-4259

CD73, also known as ecto-5’-nucleotidase, is implicated in promoting immunosuppressive tumor microenvironment (TME) through production of adenosine. The first generation of anti-CD73 therapeutic antibodies currently in clinical studies have largely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a0589dca6757164ab9a7dcfe8f9fc9e
https://doi.org/10.1158/1538-7445.am2022-4259

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