Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lauren N. Carnevale"'
Autor:
William R. Arnold, Lauren N. Carnevale, Zili Xie, Javier L. Baylon, Emad Tajkhorshid, Hongzhen Hu, Aditi Das
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Endocannabinoids are ligands of cannabinoid receptors and a promising target for pain management. Here, the authors report a class of lipids formed by the epoxidation of N-arachidonoyl dopamine and N-arachidonoyl serotonin by cytochrome P450 epoxygen
Externí odkaz:
https://doaj.org/article/e9b14b21f1074585aeec1d71675686bb
Biological phenomena ranging from enzymatic catalysis to synaptic transmission find their origins in the morphological fluctuations of biomolecules and biomolecular assemblies in liquid water. However, directly imaging these nanoscopic dynamics witho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a86fe15600c41b2f6a1755110f56e7a9
https://doi.org/10.1101/2022.11.13.516315
https://doi.org/10.1101/2022.11.13.516315
Autor:
Chang-ki Oh, Tomohiro Nakamura, Nathan Beutler, Xu Zhang, Juan Piña-Crespo, Maria Talantova, Swagata Ghatak, Dorit Trudler, Lauren N. Carnevale, Scott R. McKercher, Malina A. Bakowski, Jolene K. Diedrich, Amanda J. Roberts, Ashley K. Woods, Victor Chi, Anil K. Gupta, Mia A. Rosenfeld, Fiona L. Kearns, Lorenzo Casalino, Namir Shaabani, Hejun Liu, Ian A. Wilson, Rommie E. Amaro, Dennis R. Burton, John R. Yates, Cyrus Becker, Thomas F. Rogers, Arnab K. Chatterjee, Stuart A. Lipton
Publikováno v:
Nat Chem Biol
bioRxiv
Nature chemical biology, vol 19, iss 3
bioRxiv
Nature chemical biology, vol 19, iss 3
Prevention of infection and propagation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a high priority in the Coronavirus Disease 2019 (COVID-19) pandemic. Here we describe S-nitrosylation of multiple proteins involved in SARS-CoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56dbbfbb07a25bd2fb1950e211865c3
https://europepmc.org/articles/PMC10127945/
https://europepmc.org/articles/PMC10127945/
Autor:
Chang-ki Oh, Tomohiro Nakamura, Nathan Beutler, Xu Zhang, Juan Piña-Crespo, Maria Talantova, Swagata Ghatak, Dorit Trudler, Lauren N. Carnevale, Scott R. McKercher, Malina A. Bakowski, Jolene K. Diedrich, Amanda J. Roberts, Ashley K. Woods, Victor Chi, Anil K. Gupta, Mia A. Rosenfeld, Fiona L. Kearns, Lorenzo Casalino, Namir Shaabani, Hejun Liu, Ian A. Wilson, Rommie E. Amaro, Dennis R. Burton, John R. Yates, Cyrus Becker, Thomas F. Rogers, Arnab K. Chatterjee, Stuart A. Lipton
Prevention of infection and propagation of SARS-CoV-2 is of high priority in the COVID-19 pandemic. Here, we describe S-nitrosylation of multiple proteins involved in SARS-CoV-2 infection, including angiotensin converting enzyme 2 (ACE2), the recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58752c9c933d0e60be78b4110ba8ac35
https://doi.org/10.1101/2022.04.05.487060
https://doi.org/10.1101/2022.04.05.487060
Autor:
Emad Tajkhorshid, Javier L. Baylon, Lauren N. Carnevale, Aditi Das, William R. Arnold, Zili Xie, Hongzhen Hu
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
The endocannabinoid system is a promising target to mitigate pain as the endocannabinoids are endogenous ligands of the pain-mediating receptors—cannabinoid receptors 1 and 2 (CB1 and CB2) and TRPV1. Herein, we report on a class of lipids formed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772ccaceb8fe1fdbc65f161709660ecc
https://doi.org/10.1101/2020.05.05.079624
https://doi.org/10.1101/2020.05.05.079624
Autor:
Lauren N, Carnevale, Aditi, Das
Publikováno v:
Advances in experimental medicine and biology. 1161
Accumulating evidence suggests that diets rich in ω-3 polyunsaturated fatty acids (PUFAs) offer protection against vascular inflammation, neuroinflammation, hypertension, and thrombosis. Recently, biochemical studies have demonstrated that these ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5338af361177491866da9aaf87ea00f3
https://pubmed.ncbi.nlm.nih.gov/31562632
https://pubmed.ncbi.nlm.nih.gov/31562632
Autor:
Austin T. Weigle, Hannah C. Huff, Aditi Das, William R. Arnold, Lauren N. Carnevale, Justin S. Kim
Publikováno v:
Pharmacol Ther
Cytochrome P450 (CYP) epoxygenases are a special subset of heme-containing CYP enzymes capable of performing the epoxidation of polyunsaturated fatty acids (PUFA) and the metabolism of xenobiotics. This dual functionality positions epoxygenases along
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7386dcbb281f7835217a4dcd12a7e665
https://pubmed.ncbi.nlm.nih.gov/32534953
https://pubmed.ncbi.nlm.nih.gov/32534953
Autor:
Lauren N. Carnevale, Aditi Das
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030216368
Accumulating evidence suggests that diets rich in ω-3 polyunsaturated fatty acids (PUFAs) offer protection against vascular inflammation, neuroinflammation, hypertension, and thrombosis. Recently, biochemical studies have demonstrated that these ben
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7937c04e37c5035778d5080b496bbb5
https://doi.org/10.1007/978-3-030-21735-8_17
https://doi.org/10.1007/978-3-030-21735-8_17
Autor:
Michael J. Weingarten, Aditi Das, Nu Chu Liang, Lauren N. Carnevale, Wen Xuan Law, Nnamdi G. Nelson
RATIONALE: Whereas co-use of alcohol and marijuana is prevalent in adolescents, the effects of such drug co-exposure on ingestive and cognitive behaviors remain largely unexplored. We hypothesized that co-exposure to alcohol and Δ(9)-tetrahydrocanna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94da9738f4dd7d0b32a561f743def52d
https://europepmc.org/articles/PMC6401297/
https://europepmc.org/articles/PMC6401297/
Publikováno v:
Biochemistry. 57(46)
The human body contains endogenous cannabinoids (endocannabinoids) that elicit similar effects as Δ9-tetrahydrocanabinol, the principal bioactive component of cannabis. The endocannabinoid virodhamine (O-AEA) is the constitutional isomer of the well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c6579c096b750d1b472da34be2a389
https://pubmed.ncbi.nlm.nih.gov/30285425
https://pubmed.ncbi.nlm.nih.gov/30285425