Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Lauren N. Ayton"'
Autor:
Alexis Ceecee Britten-Jones, Joshua Schultz, Heather G. Mack, Lisa S. Kearns, Aamira J. Huq, Jonathan B. Ruddle, David A. Mackey, Alex W. Hewitt, Thomas L. Edwards, Lauren N. Ayton
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study evaluated patient experiences with genetic testing for inherited retinal diseases (IRDs) and the association between underlying knowledge, testing outcomes, and the perceived value of the results. An online survey was distributed
Externí odkaz:
https://doaj.org/article/c77e2b459ac246a794c86c5b38e23017
Autor:
Matthew A. Petoe, BEng (Hons), PhD, Carla J. Abbott, BOptom, PhD, Samuel A. Titchener, BEng (Hons), PhD, Maria Kolic, BOrth, William G. Kentler, BEng, David A.X. Nayagam, BEng (Hons), PhD, Elizabeth K. Baglin, BOrth, Jessica Kvansakul, MSc, PhD, Nick Barnes, PhD, Janine G. Walker, PhD, Lewis Karapanos, BBMed (Hons), MD, Myra B. McGuinness, MBiostat, PhD, Lauren N. Ayton, BOptom, PhD, Chi D. Luu, BOrth (Hons), PhD, Penelope J. Allen, MBBS, FRANZCO, Peter J. Blamey, Robert J. Briggs, Owen Burns, Stephanie B. Epp, Dean Johnson, Hugh J. McDermott, Ceara McGowan, Rodney E. Millard, Peter M. Seligman, Robert K. Shepherd, Mohit N. Shivdasani, Nicholas C. Sinclair, Patrick C. Thien, Joel Villalobos, Chris E. Williams, Jonathan Yeoh, Kiera A. Young
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100525- (2025)
Purpose: To assess the feasibility of a second-generation (44-channel) suprachoroidal retinal prosthesis for provision of functional vision in recipients with end-stage retinitis pigmentosa (RP) over 2.7 years. Design: Prospective, single-arm, unmask
Externí odkaz:
https://doaj.org/article/3a20a1a10d28475b9c47d7d3672f0e3e
Autor:
Alexis Ceecee Britten-Jones, Demi Markakis, Robyn H. Guymer, Ming-Lee Lin, Simon Skalicky, Lauren N. Ayton, Heather G. Mack
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractPurpose Accurate diagnosis of macular atrophy is paramount to enable appropriate treatment when novel treatments for geographic atrophy and macular dystrophies become available. Genetic testing is useful in distinguishing between the two cond
Externí odkaz:
https://doaj.org/article/4412ff98cde247379b30df36216589e2
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Vernier acuity measures the ability to detect a misalignment or positional offset between visual stimuli, for example between two vertical lines when reading a vernier scale. It is considered a form of visual hyperacuity due to its detectable thresho
Externí odkaz:
https://doaj.org/article/499a0adbf5554b24967eb7581356180a
Autor:
Alexis Ceecee Britten-Jones, Sena A. Gocuk, Kai Lyn Goh, Aamira Huq, Thomas L. Edwards, Lauren N. Ayton
Publikováno v:
American Journal of Ophthalmology. 249:57-73
Accurate genotyping of individuals with inherited retinal diseases (IRD) is essential for patient management and identifying suitable candidates for gene therapies. This study evaluated the diagnostic yield of next generation sequencing (NGS) in IRDs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ad7b4e00896230d16fa5f2c6e15269
https://doi.org/10.1016/j.ajo.2022.12.027
https://doi.org/10.1016/j.ajo.2022.12.027
Autor:
Timothy R. Fricke, Lisa Keay, Serge Resnikoff, Nina Tahhan, Ornella Koumbo, Prakash Paudel, Lauren N. Ayton, Alexis Ceecee Britten‐Jones, Suhyun Kweon, Josephine C. H. Li, Ling Lee, Peter Wagner, Rebecca Weng, Boris Beranger, Jake Olivier
Publikováno v:
Ophthalmic and Physiological Optics. 43:445-453
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47f9073f882a4ae2c99729d2bec42572
https://doi.org/10.1111/opo.13105
https://doi.org/10.1111/opo.13105
Survey of perspectives of people with inherited retinal diseases on ocular gene therapy in Australia
Autor:
Heather G. Mack, Alexis Ceecee Britten-Jones, Myra B. McGuinness, Fred K. Chen, John R. Grigg, Robyn V. Jamieson, Thomas L. Edwards, John De Roach, Fleur O’Hare, Keith R. Martin, Lauren N. Ayton
Publikováno v:
Gene Therapy. 30:336-346
Many gene therapies are in development for treating people with inherited retinal diseases (IRD). We hypothesized that potential recipients of gene therapy would have knowledge gaps regarding treatment. We aimed to assess knowledge, attitudes, and pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::948216fe43ce929e26a5e2c099b66056
https://doi.org/10.1038/s41434-022-00364-z
https://doi.org/10.1038/s41434-022-00364-z
Publikováno v:
Clinical & Experimental Ophthalmology. 50:768-780
Emerging treatments are being developed for inherited retinal diseases, requiring a clear understanding of natural progression and a database of potential participants for clinical trials. This article describes the rationale, study design and method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ade8104ecd0491af942405e8c26ade7
https://doi.org/10.1111/ceo.14110
https://doi.org/10.1111/ceo.14110
Autor:
Rachael C. Heath Jeffery, Johnny Lo, Jennifer A. Thompson, Tina M. Lamey, Terri L. McLaren, John N. De Roach, Lauren N. Ayton, Andrea L. Vincent, Abhishek Sharma, Fred K. Chen
Publikováno v:
Ophthalmology Retina.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b880d65df43c412720c3dc4087a9da0f
https://doi.org/10.1016/j.oret.2023.05.010
https://doi.org/10.1016/j.oret.2023.05.010
Autor:
Alexis Ceecee Britten-Jones, Rui Jin, Lauren N Ayton, Doron G. Hickey, Sena A. Gocuk, Elise Cichello, Fleur O'Hare, Thomas L Edwards
Publikováno v:
Genetics in Medicine. 24:521-534
This study aimed to systematically review and summarize gene therapy treatment for monogenic retinal and optic nerve diseases.This review was prospectively registered (CRD42021229812). A comprehensive literature search was performed in Ovid MEDLINE,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c651aa589d251db8c892c012f9ec18f1
https://doi.org/10.1016/j.gim.2021.10.013
https://doi.org/10.1016/j.gim.2021.10.013