Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Lauren Mills"'
Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma
Autor:
Erdong Wei, Ana Mitanoska, Quinn O’Brien, Kendall Porter, MacKenzie Molina, Haseeb Ahsan, Usuk Jung, Lauren Mills, Michael Kyba, Darko Bosnakovski
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Ewing sarcoma (ES) poses a significant therapeutic challenge due to the difficulty in targeting its main oncodriver, EWS::FLI1. We show that pharmacological targeting of the EWS::FLI1 transcriptional complex via inhibition of P300/CBP drives
Externí odkaz:
https://doaj.org/article/3923b7e698e143889b1d963ad608e92e
Autor:
Zicheng Wang, Yunong Xia, Lauren Mills, Athanasios N. Nikolakopoulos, Nicole Maeser, Scott M. Dehm, Jason M. Sheltzer, Ruping Sun
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The timing and fitness effect of somatic copy number alterations (SCNA) in cancer evolution remains poorly understood. Here we present a framework to determine the timing of a clonal SCNA that encompasses multiple gains. This involves calcul
Externí odkaz:
https://doaj.org/article/a2aa4e2c332c42c18d976ced25f4b625
Autor:
Lauren Mills, Melanie M. Randall
Publikováno v:
Case Reports in Pediatrics, Vol 2021 (2021)
Disseminated coccidioidomycosis is a disease caused by Coccidioides species, fungi endemic to the southwestern United States. We present here an uncommon case of a young child with erythema nodosum and fever of unknown origin, found to have the infec
Externí odkaz:
https://doaj.org/article/bd37730353434f178a6ccb4ffeb8af64
Publikováno v:
Microplastics and Nanoplastics. 3
Plastic pollution is now so widespread that microplastics are regularly detected in biological samples surveyed for their presence. Despite their pervasiveness, very little is known about the effects of microplastics on the health of terrestrial vert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8185ecf20719672029b2afa2329da6f7
https://doi.org/10.1186/s43591-023-00059-1
https://doi.org/10.1186/s43591-023-00059-1
Autor:
Jenna B. Mendelson, Jacob D. Sternbach, Michelle J. Doyle, Lauren Mills, Lynn M. Hartweck, Walt Tollison, John P. Carney, Matthew T. Lahti, Richard W. Bianco, Rajat Kalra, Felipe Kazmirczak, Charles Hindmarch, Stephen L Archer, Kurt W. Prins, Cindy M. Martin
Publikováno v:
bioRxiv
Right ventricular failure (RVF) is a leading cause of morbidity and mortality in multiple cardiovascular diseases, but there are no approved treatments for RVF as therapeutic targets are not clearly defined. Contemporary transcriptomic/proteomic eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2dab5f715ca11157c7fc5c84ff0117
https://europepmc.org/articles/PMC9934613/
https://europepmc.org/articles/PMC9934613/
Recent years have seen considerable scientific attention devoted towards documenting the presence of microplastics (MPs) in environmental samples. Due to omnipresence of environmental microplastics, however, disentangling environmental MPs from sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec68ea87a6fb420c094085cb6a354c08
https://doi.org/10.1101/2023.02.04.527118
https://doi.org/10.1101/2023.02.04.527118
Plastic pollution is now so widespread that microplastics are consistently detected in every biological sample surveyed for their presence. Despite their pervasiveness, very little is known about the effects of microplastics on the health of terrestr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdcdd9913f2f7921d5ca9d1a47fe3de0
https://doi.org/10.1101/2022.11.21.517421
https://doi.org/10.1101/2022.11.21.517421
Autor:
Zicheng Wang, Yunong Xia, Lauren Mills, Athanasios N. Nikolakopoulos, Nicole Maeser, Jason M. Sheltzer, Ruping Sun
Charting the evolutionary history of rampant somatic copy number alterations (SCNA) is an indispensable step toward a deeper understanding of their roles in tumor development. However, the existing SCNA timing analysis is limited to low copy number s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ffe15147d128ec384e3686ddd4f5ae3
https://doi.org/10.1101/2022.06.14.495959
https://doi.org/10.1101/2022.06.14.495959
Autor:
Melanie M Randall, Lauren Mills
Publikováno v:
Case Reports in Pediatrics, Vol 2021 (2021)
Case Reports in Pediatrics
Case Reports in Pediatrics
Disseminated coccidioidomycosis is a disease caused by Coccidioides species, fungi endemic to the southwestern United States. We present here an uncommon case of a young child with erythema nodosum and fever of unknown origin, found to have the infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68a930b93a4ffc42da5ff1c31248072
https://doaj.org/article/bd37730353434f178a6ccb4ffeb8af64
https://doaj.org/article/bd37730353434f178a6ccb4ffeb8af64
Autor:
Alex Smith, Lauren Mills Taylor
Publikováno v:
Yearbook of International Environmental Law. 29:205-209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7b72e4ca4df37d409838d00ec37a85e
https://doi.org/10.1093/yiel/yvz046
https://doi.org/10.1093/yiel/yvz046