Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lauren Melrose"'
Autor:
Sofia Sintoris, Justyna M. Binkowska, Jonathan L. Gillan, Roy P. Zuurbier, Jonathan Twynam-Perkins, Maartje Kristensen, Lauren Melrose, Paula Lusaretta Parga, Alicia Ruiz Rodriguez, Mei Ling Chu, Sara R. van Boeckel, Joanne G. Wildenbeest, Dawn M. E. Bowdish, Andrew J. Currie, Ryan S. Thwaites, Jurgen Schwarze, Marlies A. van Houten, James P. Boardman, Steve Cunningham, Debby Bogaert, Donald J. Davidson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Respiratory syncytial virus is the major cause of acute lower respiratory tract infections in young children, causing extensive mortality and morbidity globally, with limited therapeutic or preventative options. Cathelicidins are innate immu
Externí odkaz:
https://doaj.org/article/7a315c29b5364d6da9023a1485e4aecf
Autor:
Katie J Smith, Danielle Minns, Brian J McHugh, Rebecca K Holloway, Richard O'Connor, Anna Williams, Lauren Melrose, Rhoanne McPherson, Veronique E Miron, Donald J Davidson, Emily Gwyer Findlay
Publikováno v:
PLoS Biology, Vol 20, Iss 8, p e3001554 (2022)
Multiple sclerosis (MS) is a highly prevalent demyelinating autoimmune condition; the mechanisms regulating its severity and progression are unclear. The IL-17-producing Th17 subset of T cells has been widely implicated in MS and in the mouse model,
Externí odkaz:
https://doaj.org/article/6092c03798ea4893825a68dc61de5313
Autor:
Danielle Minns, Katie J. Smith, Virginia Alessandrini, Gareth Hardisty, Lauren Melrose, Lucy Jackson-Jones, Andrew S. MacDonald, Donald J. Davidson, Emily Gwyer Findlay
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of
Externí odkaz:
https://doaj.org/article/575b66e7e8b04cad96678a2c55c7e867
Autor:
Fiona Semple, Heather MacPherson, Sheila Webb, Fiona Kilanowski, Laura Lettice, Sarah L McGlasson, Ann P Wheeler, Valerie Chen, Glenn L Millhauser, Lauren Melrose, Donald J Davidson, Julia R Dorin
Publikováno v:
PLoS Genetics, Vol 12, Iss 1, p e1005801 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1005673.].
Externí odkaz:
https://doaj.org/article/22629890b1184e4cb180d81aabec403d
Autor:
Fiona Semple, Heather MacPherson, Sheila Webb, Fiona Kilanowski, Laura Lettice, Sarah L McGlasson, Ann P Wheeler, Valerie Chen, Glenn L Millhauser, Lauren Melrose, Donald J Davidson, Julia R Dorin
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005673 (2015)
Human β-defensin 3 (hBD3) is a cationic host defence peptide and is part of the innate immune response. HBD3 is present on a highly copy number variable block of six β-defensin genes, and increased copy number is associated with the autoimmune dise
Externí odkaz:
https://doaj.org/article/9377eba321364004bd58cd30a540c911
Autor:
Katie J. Smith, Danielle Minns, Brian J. McHugh, Rebecca K. Holloway, Richard O’Connor, Anna Williams, Lauren Melrose, Rhoanne McPherson, Veronique E. Miron, Donald J. Davidson, Emily Gwyer Findlay
Publikováno v:
Smith, K, Minns, D, McHugh, B, Holloway, R, O'Connor, R A, Williams, A C, Melrose, L, McPherson, R, Miron, V E, Davidson, D J & Gwyer Findlay, E L 2022, ' The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation ', PLoS Biology . https://doi.org/10.1371/journal.pbio.3001554
Multiple sclerosis (MS) is a highly prevalent demyelinating autoimmune condition; the mechanisms regulating its severity and progression are unclear. The IL-17-producing Th17 subset of T cells has been widely implicated in MS and in the mouse model,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177cf162efca07578b4796b727daf078
https://www.pure.ed.ac.uk/ws/files/297738163/journal.pbio.3001554.pdf
https://www.pure.ed.ac.uk/ws/files/297738163/journal.pbio.3001554.pdf
Autor:
Donald J. Davidson, Lauren Melrose, Fiona Kilanowski, Sarah McGlasson, Julia R. Dorin, Valerie Chen, Heather MacPherson, Ann P. Wheeler, Laura A. Lettice, Glenn L. Millhauser, Sheila Webb, Fiona Semple
Publikováno v:
Semple, F, MacPherson, H, Webb, S, Kilanowski, F, Lettice, L, McGlasson, S L, Wheeler, A P, Chen, V, Millhauser, G L, Melrose, L, Davidson, D J & Dorin, J R 2015, ' Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid ', PLoS Genetics, vol. 11, no. 12, e1005673 . https://doi.org/10.1371/journal.pgen.1005673
PLoS Genetics
PLoS Genetics
Human β-defensin 3 (hBD3) is a cationic host defence peptide and is part of the innate immune response. HBD3 is present on a highly copy number variable block of six β-defensin genes, and increased copy number is associated with the autoimmune dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81aeedffce782eedc2ec68dee3d32baf
https://www.pure.ed.ac.uk/ws/files/22955021/hBD3_exacerbates_MDA5_but_suppresses_TLR3_signalling.pdf
https://www.pure.ed.ac.uk/ws/files/22955021/hBD3_exacerbates_MDA5_but_suppresses_TLR3_signalling.pdf