Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lauren M. Timmins"'
Autor:
Lauren M. Timmins, Alexandra M. Burr, Kristina Carroll, Robert Keefe, Matthew Teryek, Louis J. Cantolupo, Johannes C. M. van der Loo, Thomas R.J. Heathman, Adam J Gormley, David Smith, Biju Parekkadan
Publikováno v:
Cell Transplantation, Vol 30 (2021)
When considering the development pathway for a genetically modified cell therapy product, it is critically important that the product is engineered consistent with its intended human use. For scientists looking to develop and commercialize a new tech
Externí odkaz:
https://doaj.org/article/91127e337b6748c391d23c6b3e15f54f
Autor:
Frederique M. Poulet, J. Michael Ellis, Matthew E. Kennedy, Carrie G. Markgraf, Lauren M Timmins, Dianne K. Bryce, Sabu Kuruvilla, Janice D Woodhouse, Matthew J. Fell, Karin M. Otte, Christopher Ware, Laxminarayan G Hegde, Matthew L. Maddess, Paul J Ciaccio
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 377:11-19
Gain-of-function mutations in leucine-rich kinase 2 (LRRK2) are associated with increased incidence of Parkinson disease (PD); thus, pharmacological inhibition of LRRK2 kinase activity is postulated as a disease-modifying treatment of PD. Histomorpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f51a63a6fe69d40bfa5ed39544e2dd
https://doi.org/10.1124/jpet.120.000217
https://doi.org/10.1124/jpet.120.000217
Autor:
Paulina Krzyszczyk, Max L. Balter, Erika J Davidoff, Ileana Marrero-Berrios, Corina White, Joseph J. Sherba, Kate O'Neill, Zachary Fritz, Misaal Patel, Rene S. Schloss, Christopher J. Lowe, Alison Acevedo, Martin L. Yarmush, Ioannis P. Androulakis, Clara Hartmanshenn, Lauren M Timmins
Publikováno v:
Technology
Cancer is a devastating disease that takes the lives of hundreds of thousands of people every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or radiation, are effective in only a subset of the patient population. Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450900e15e92f91c1330339447de166e
http://europepmc.org/articles/PMC6352312
http://europepmc.org/articles/PMC6352312
Autor:
Rachana Bhatt, Biju Parekkadan, John Lucas, Riya S. Patel, Shilpaa Mukundan, Aimee M. Beaulieu, Matthew Teryek, Lauren M Timmins
Publikováno v:
J Immunol Methods
Natural Killer (NK) cells are lymphocytes that are the first line of defense against malignantly transformed cells, virally infected cells and other stressed cell types. To study the cytolytic function of NK cells in vitro, a cytotoxicity assay is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd3baa0bf03e171a47b0bd7648e0859e
https://europepmc.org/articles/PMC8112353/
https://europepmc.org/articles/PMC8112353/
Autor:
Kristina Carroll, Johannes C.M. Van der Loo, Lauren M Timmins, Thomas R.J. Heathman, David Smith, Alexandra Burr, Biju Parekkadan, Robert Keefe, Louis J. Cantolupo, Adam J. Gormley, Matthew Teryek
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 30 (2021)
Cell Transplantation, Vol 30 (2021)
When considering the development pathway for a genetically modified cell therapy product, it is critically important that the product is engineered consistent with its intended human use. For scientists looking to develop and commercialize a new tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a091ac2e3e5653121581c60c4711ee3
https://doi.org/10.1177/09636897211003022
https://doi.org/10.1177/09636897211003022