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of 11
pro vyhledávání: '"Lauren M. Moore"'
Neuronal Calcium Sensor 1 (NCS-1) is a multi-functional Ca2+-binding protein that affects a range of cellular processes beyond those related to neurons. Functional characterization of NCS-1 in neuronal model systems suggests that NCS-1 may influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c590483433f1190b026312f39e3506e6
https://doi.org/10.1158/1541-7786.c.6541099
https://doi.org/10.1158/1541-7786.c.6541099
Figure 1: NCS-1 and its Known Binding Partners: This web diagram illustrates the binding partners of NCS-1. Figure 2: Assessment of the effect of NCS-1 on Motility: Representative photomicrographs from scratch motility assays for A. Figure 3: NCS-1 M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6539b9ebb7e7c5ad19476be5847e8504
https://doi.org/10.1158/1541-7786.22515481.v1
https://doi.org/10.1158/1541-7786.22515481.v1
Figure 1: NCS-1 and its Known Binding Partners. Figure 2: Assessment of the effect of NCS-1 on Motility. Figure 3: NCS-1 May Promote Tumor Aggressiveness by Altering Invasion and Chemotaxis. Figure 4: NCS-1 May Promote Tumor Aggressiveness by Alterin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e2e4a326ab88c87fcfc683e01744af
https://doi.org/10.1158/1541-7786.22515484.v1
https://doi.org/10.1158/1541-7786.22515484.v1
Autor:
Barbara E. Ehrlich, Lauren M. Moore, John J. McGuire, David L. Rimm, Maria I. Toki, Rachel Wilkinson, Mehmet Altan, Daniel E. Carvajal-Hausdorf
Publikováno v:
npj Breast Cancer, Vol 4, Iss 1, Pp 1-3 (2018)
NPJ Breast Cancer
NPJ Breast Cancer
Neuronal calcium sensor-1 (NCS-1) has been identified as a binding partner of the taxane, paclitaxel. Our previous study showed that overexpression of NCS-1 increased the efficacy of paclitaxel in vitro, but was associated with poor clinical outcome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9592f771ee31118d95c20ccda99314e
http://link.springer.com/article/10.1038/s41523-018-0057-7
http://link.springer.com/article/10.1038/s41523-018-0057-7
Autor:
Lauren M. Moore, Lakshmi V. Ramanathan
Publikováno v:
Clinical chemistry. 65(10)
A 64-year-old man with mantle cell lymphoma was intubated owing to respiratory insufficiency. His condition improved, and his physician was considering extubating him. However, there was concern over his most recent pO2 value obtained by arterial blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3fa40bfbd7ae644d054e974ffb5aa01
https://pubmed.ncbi.nlm.nih.gov/31570417
https://pubmed.ncbi.nlm.nih.gov/31570417
Autor:
Eunhee S. Yi, Daniel T. Merrick, Lauren M. Moore, Hadi Yaziji, Richard W. Cartun, Lynette M. Sholl, Patricia Gaule, Allen M. Gown, Jason L. Hornick, John J. McGuire, Balazs Acs, Jingxin Qiu, Zhong J. Zhang, David L. Rimm, Mary Beth Beasley, Jill Walker, Wei-Lien Wang, Delphine Cougot, Abiy B. Ambaye, Sandra Martinez-Morilla, Mari Mino-Kenudson
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Programmed death 1 ligand 1 (PD-L1) Immunohistochemistry (IHC) is the key FDA-approved predictive marker to identify responders to anti-PD1 axis drugs. Multiple PD-L1 IHC assays with various antibodies and cut points have been used in clinical trials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1e5cf2c83be1eafb11019058c4ef3a
https://pubmed.ncbi.nlm.nih.gov/31409885
https://pubmed.ncbi.nlm.nih.gov/31409885
Publikováno v:
Clin Chim Acta
Background Daratumumab, a therapeutic IgG kappa monoclonal antibody, can cause a false positive interference on electrophoretic assays that are routinely used to monitor patients with monoclonal gammopathies. In this study, we evaluate the ability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd67f8a4ccfaac39a07cf71e051162e8
https://europepmc.org/articles/PMC6524149/
https://europepmc.org/articles/PMC6524149/
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide. There is an urgent demand for prognostic biomarkers that facilitate early tumor detection, as the incidence of HCC has tripled in the United Sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0614e8e6813d431fee968f122d187ba2
https://pubmed.ncbi.nlm.nih.gov/29789326
https://pubmed.ncbi.nlm.nih.gov/29789326
Autor:
James W. Smithy, Patricia Gaule, Veronique Neumeister, Pok Fai Wong, Mario Sznol, David L. Rimm, Vasiliki Pelekanou, Lauren M. Moore, Jamaal Rehman, Harriet M. Kluger
Publikováno v:
Journal for Immunotherapy of Cancer
Background Predictive biomarkers for antibodies against programmed death 1 (PD-1) remain a major unmet need in metastatic melanoma. Specifically, response is seen in tumors that do not express programmed death ligand 1 (PD-L1), highlighting the need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd9d3e4606bcdfa8928b470976cd290
https://doi.org/10.1186/s40425-017-0229-2
https://doi.org/10.1186/s40425-017-0229-2
Neuronal Calcium Sensor 1 (NCS-1) is a multi-functional Ca2+-binding protein that affects a range of cellular processes beyond those related to neurons. Functional characterization of NCS-1 in neuronal model systems suggests that NCS-1 may influence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cfea55a1c64571719d27e243b899fc
https://europepmc.org/articles/PMC5500411/
https://europepmc.org/articles/PMC5500411/