Výsledky vyhledávání - "Lauren M. Lockhart"

Sigma-1 receptors and progesterone metabolizing enzymes in nociceptive sensory neurons of the female rat trigeminal ganglia: A neural substrate for the antinociceptive actions of progesterone

Autor: Rebecca S Hornung, Namrata GR Raut, Daisy J Cantu, Lauren M Lockhart, Dayna L Averitt

Publikováno v: Molecular Pain

Orofacial pain disorders are predominately experienced by women. Progesterone, a major ovarian hormone, is neuroprotective and antinociceptive. We recently reported that progesterone attenuates estrogen-exacerbated orofacial pain behaviors, yet it re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76341f867ec35b84a87fd91d05c8b3e
https://pubmed.ncbi.nlm.nih.gov/35040378

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Estrogen modulation of the pronociceptive effects of serotonin on female rat trigeminal sensory neurons is timing dependent and dosage dependent and requires estrogen receptor alpha

Autor: Sukhbir Kaur, Taylor M. Hickman, Angela Lopez-Ramirez, Hanna McDonald, Lauren M. Lockhart, Omar Darwish, Dayna Loyd Averitt

Publikováno v: Pain. 163(8)

The role of the major estrogen estradiol (E2) on orofacial pain conditions remains controversial with studies reporting both a pronociceptive and antinociceptive role of E2. E2 modulation of peripheral serotonergic activity may be one mechanism under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9557e209cc91177597d0c91fbb3360d
https://pubmed.ncbi.nlm.nih.gov/35121697

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