Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lauren M. LaRocque"'
Autor:
Yanhua Wang, Lauren M. LaRocque, Joseph A. Ruiz, Eva L. Rodriguez, Jeff M. Sands, Janet D. Klein
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1844 (2023)
Hyponatremia (hypo-osmolality) is a disorder of water homeostasis due to abnormal renal diluting capacity. The body limits the degree to which serum sodium concentration falls through a mechanism called “vasopressin escape”. Vasopressin escape is
Externí odkaz:
https://doaj.org/article/5198fd45c4024b5dabe674b0e5b2153e
Autor:
Janet D. Klein, Ish Khanna, Ram Pillarisetti, Rachael A. Hagan, Lauren M. LaRocque, Eva L. Rodriguez, Jeff M. Sands
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Nephrogenic diabetes insipidus (NDI) patients produce large amounts of dilute urine. NDI can be congenital, resulting from mutations in the type-2 vasopressin receptor (V2R), or acquired, resulting from medications such as lithium. There are no effec
Externí odkaz:
https://doaj.org/article/3e000dbabb104220804b90dc7a55720c
Autor:
Klein, Yanhua Wang, Lauren M. LaRocque, Joseph A. Ruiz, Eva L. Rodriguez, Jeff M. Sands, Janet D.
Publikováno v:
Biomedicines; Volume 11; Issue 7; Pages: 1844
Hyponatremia (hypo-osmolality) is a disorder of water homeostasis due to abnormal renal diluting capacity. The body limits the degree to which serum sodium concentration falls through a mechanism called “vasopressin escape”. Vasopressin escape is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::006ff9cb7ccb0a153c5dd479f9b1d89d
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91b466f00fccdd94dc1cb120508ca4ed
https://doi.org/10.1096/fasebj.2022.36.s1.r2770
https://doi.org/10.1096/fasebj.2022.36.s1.r2770
Autor:
Ram Pillarisetti, Lauren M. LaRocque, Jeff M. Sands, Ish Khanna, Eva L. Rodriguez, Rachael A. Hagan, Janet D. Klein
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
JCI Insight
JCI Insight
Nephrogenic diabetes insipidus (NDI) patients produce large amounts of dilute urine. NDI can be congenital, resulting from mutations in the type-2 vasopressin receptor (V2R), or acquired, resulting from medications such as lithium. There are no effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868bdf4f3e20c30f8e0fb535a51fea8e
https://doi.org/10.1172/jci.insight.146419
https://doi.org/10.1172/jci.insight.146419
Autor:
Janet D. Klein, Yanhua Wang, Joseph A. Ruiz, Lauren M. LaRocque, Mitsi A. Blount, Patrick A. Molina, Jeff M. Sands
Publikováno v:
American Journal of Physiology-Renal Physiology. 310:F1008-F1012
Nephrogenic diabetes insipidus (NDI) is characterized by production of very large quantities of dilute urine due to an inability of the kidney to respond to vasopressin. Congenital NDI results from mutations in the type 2 vasopressin receptor (V2R) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b658c84e0c7450e8c8d269028a458431
https://doi.org/10.1152/ajprenal.00102.2016
https://doi.org/10.1152/ajprenal.00102.2016
Autor:
Joseph A. Ruiz, Yanhua Wang, Fuying Ma, Lauren M. LaRocque, Josephine K. Liwang, Fitra Rianto
Publikováno v:
American journal of physiology. Renal physiology. 316(2)
Hypertonicity increases water permeability, independently of vasopressin, in the inner medullary collecting duct (IMCD) by increasing aquaporin-2 (AQP2) membrane accumulation. We investigated whether protein kinase C (PKC) and adenosine monophosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d16f0cb8b8605283a68d0793852a10e
https://pubmed.ncbi.nlm.nih.gov/30427219
https://pubmed.ncbi.nlm.nih.gov/30427219
Autor:
Lauren M. LaRocque, Mitsi A. Blount, Patrick A. Molina, Abinash Chandra Mistry, Yanhua Wang, Janet D. Klein, Richard T. Rogers, Jeff M. Sands
Publikováno v:
Journal of the American Society of Nephrology. 27:1448-1455
Urea has a critical role in urinary concentration. Mice lacking the inner medullary collecting duct (IMCD) urea transporter A1 (UT-A1) and urea transporter A3 (UT-A3) have very low levels of urea permeability and are unable to concentrate urine. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c44281470c34f0992a8695868c154370
https://doi.org/10.1681/asn.2014121267
https://doi.org/10.1681/asn.2014121267
Autor:
Janet D. Klein, Daisuke Nakano, Friedrich C. Luft, Raymond C. Harris, Jeff M. Sands, Tetyana V. Pedchenko, Agnes Schröder, Jonathan Jantsch, Dominik N. Müller, Lauren M. LaRocque, Akira Nishiyama, Jens Titze, Anna Dikalova, Adriana Marton, Manfred Rauh, Steffen Daub, Sergey Dikalov, Patrick Neubert, Natalia Rakova, Kento Kitada, Louise Lantier, David G. Harrison, David H. Wasserman, Yahua Zhang
Natriuretic regulation of extracellular fluid volume homeostasis includes suppression of the renin-angiotensin-aldosterone system, pressure natriuresis, and reduced renal nerve activity, actions that concomitantly increase urinary Na+ excretion and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f4b075cd2f5073a70c0883aece2ac4
http://edoc.mdc-berlin.de/16467/1/16467oa.pdf
http://edoc.mdc-berlin.de/16467/1/16467oa.pdf
Publikováno v:
JCI Insight. 1
Urine concentration is regulated by vasopressin. Congenital nephrogenic diabetes insipidus (NDI) is caused by vasopressin type 2 receptor (V2R) mutations. We studied whether metformin could improve urine concentration in rodent models of congenital N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a96f0142ee7fee7ca4d6f448629bb0
https://doi.org/10.1172/jci.insight.88409
https://doi.org/10.1172/jci.insight.88409