Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lauren M. Cross"'
Autor:
Aparna Murali, Anna M. Brokesh, Lauren M. Cross, Anna L. Kersey, Manish K. Jaiswal, Irtisha Singh, Akhilesh Gaharwar
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Minerals play a vital role, working synergistically with enzymes and other cofactors to regulate physiological functions including tissue healing and regeneration. The bioactive characteristics of mineral‐based nanomaterials can be harness
Externí odkaz:
https://doaj.org/article/60aa61c451d64162ad2eba36074cbc38
Autor:
Sara B. Cohen, Courtney R. Plumlee, Lindsay Engels, Dat Mai, Tara A. Murray, Ana N. Jahn, Bridget Alexander, Jared L. Delahaye, Lauren M. Cross, Karolina Maciag, Sam Schrader, Kaitlin Durga, Elizabeth S. Gold, Alan Aderem, Michael Y. Gerner, Benjamin H. Gern, Alan H. Diercks, Kevin B. Urdahl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
To investigate how host and pathogen diversity govern immunity against Mycobacterium tuberculosis (Mtb), we performed a large-scale screen of vaccine-mediated protection against aerosol Mtb infection using three inbred mouse strains [C57BL/6 (B6), C3
Externí odkaz:
https://doaj.org/article/8f1d5d9be6814725a222414224aa913c
Autor:
Anna M. Brokesh, Lauren M. Cross, Anna L. Kersey, Aparna Murali, Christopher Richter, Carl A. Gregory, Irtisha Singh, Akhilesh K. Gaharwar
Publikováno v:
Science Advances. 8
Bioactive materials harness the body’s innate regenerative potential by directing endogenous progenitor cells to facilitate tissue repair. Dissolution products of inorganic biomaterials provide unique biomolecular signaling for tissue-specific diff
Autor:
Irtisha Singh, David Chimene, Akhilesh K. Gaharwar, Logan Miller, Manish K. Jaiswal, Lauren M. Cross
Publikováno v:
ACS applied materialsinterfaces. 12(14)
Bioprinting is an emerging additive manufacturing approach to the fabrication of patient-specific, implantable three-dimensional (3D) constructs for regenerative medicine. However, developing cell-compatible bioinks with high printability, structural
We present a nanoengineered system for sustained and prolonged delivery of protein therapeutics, which has the potential to impact current orthopedic regeneration strategies. Specifically, we introduce two-dimen-sional nanosilicates with a high surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165c80555cf87b247b6fe4ae9d3b7c90
https://europepmc.org/articles/PMC6472961/
https://europepmc.org/articles/PMC6472961/
Autor:
Teena Thakur, Akhilesh K. Gaharwar, Manish K. Jaiswal, Roland Kaunas, Eli Mondragon, Lauren M. Cross, Janet R. Xavier
Publikováno v:
Journal of Biomedical Materials Research Part A. 104:879-888
Nanocomposite biomaterials are extensively investigated for cell and tissue engineering applications due their unique physical, chemical and biological characteristics. Here, we investigated the mechanical, rheological, and degradation properties of
Autor:
Lauren M. Cross, Irtisha Singh, Manish K. Jaiswal, Carl A. Gregory, Roland Kaunas, Robert W. Reese, James K. Carrow, Akhilesh K. Gaharwar
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We demonstrate the use of next-generation sequencing technology (RNA-seq) to understand the effect of a two-dimensional nanomaterial on human stem cells at the whole-transcriptome level. Our results identify more than 4,000 genes that ar
Autor:
Lauren M. Cross, Roland Kaunas, Akhilesh K. Gaharwar, Charles W. Peak, Guinea Brasil Camargo Cardoso, David Chimene, James K. Carrow, Eli Mondragon, James L. Gentry
Publikováno v:
ACS applied materialsinterfaces. 10(12)
We introduce an enhanced nanoengineered ionic-covalent entanglement (NICE) bioink for the fabrication of mechanically stiff and elastomeric 3D biostructures. NICE bioink formulations combine nanocomposite and ionic-covalent entanglement (ICE) strengt
Publikováno v:
Nanoscale. 9(40)
“Smart” hydrogels are an emerging class of biomaterials that respond to external stimuli and have been investigated for a range of biomedical applications, including therapeutic delivery and regenerative engineering. Stimuli-responsive nanogels c
Autor:
Ulf Krause, Suzanne Zeitouni, Bret H. Clough, Akhilesh K. Gaharwar, Lauren M. Cross, Christopher D. Chaput, Carl A. Gregory
Publikováno v:
Stem Cells Translational Medicine
Non-union defects of bone are a major problem in orthopedics, especially for patients with a low healing capacity. Fixation devices and osteoconductive materials are used to provide a stable environment for osteogenesis and an osteogenic component su