Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lauren M. Aufdembrink"'
Autor:
Judee A. Sharon, Chelsea Dasrath, Aiden Fujiwara, Alessandro Snyder, Mace Blank, Sam O’Brien, Lauren M. Aufdembrink, Aaron E. Engelhart, Katarzyna P. Adamala
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Biological computation is becoming a viable and fast-growing alternative to traditional electronic computing. Here we present a biocomputing technology called Trumpet: Transcriptional RNA Universal Multi-Purpose GatE PlaTform. Trumpet combin
Externí odkaz:
https://doaj.org/article/c1543b88e1da411dbcc92df1fd97c568
Autor:
Wakana Sato, B. Cash, Nathaniel J. Gaut, Christopher Deich, Aaron E. Engelhart, Joseph M. Heili, Katarzyna P. Adamala, Judee Sharon, Kaitlin Stokes, Lauren M. Aufdembrink
Publikováno v:
Journal of Biological Engineering. 17
Background Efficient cell-free protein expression from linear DNA templates has remained a challenge primarily due to template degradation. In addition, the yields of transcription in cell-free systems lag behind transcriptional efficiency of live ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd13120bf01675745b4ff90c863f92b4
https://doi.org/10.1186/s13036-023-00323-1
https://doi.org/10.1186/s13036-023-00323-1
Autor:
Tanner G. Hoog, Matthew R. Pawlak, Lauren M. Aufdembrink, Benjamin R. Bachan, Matthew B. Galles, Nicholas B. Bense, Katarzyna P. Adamala, Aaron E. Engelhart
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(9)
Here we demonstrate a switchable DNA electron-transfer catalyst, enabled by selective destabilization of secondary structure by the denaturant, perchlorate. The system is comprised of two strands, one of which can be selectively switched between a G-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966d4b5824cbf5928e82533f0a0bdc59
https://pubmed.ncbi.nlm.nih.gov/35245408
https://pubmed.ncbi.nlm.nih.gov/35245408
Autor:
Aimee M. Krebsbach, Robert Hughes, Jackie A. Heitzman, DeWayne Townsend, Tatyana A. Meyers, Alessandro Bartolomucci, Lauren M. Aufdembrink
Publikováno v:
Journal of Molecular and Cellular Cardiology. 128:51-61
Background Duchenne muscular dystrophy (DMD) is an X-linked disease characterized by skeletal muscle degeneration and a significant cardiomyopathy secondary to cardiomyocyte damage and myocardial loss. The molecular basis of DMD lies in the absence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::221a8ce1caee0e06c29856c95c92b8ea
https://doi.org/10.1016/j.yjmcc.2019.01.013
https://doi.org/10.1016/j.yjmcc.2019.01.013
Publikováno v:
ACS Synthetic Biology
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, poses grave threats to both the global economy and health. The predominant diagnostic screens in use for SARS-CoV-2 detection are molecular techniques such as nucleic acid amplification tests. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cca0238ee5f5c560ed97b1c99d6e6df
Autor:
Lauren M. Aufdembrink, Nathaniel J. Gaut, Katarzyna P. Adamala, Tanner G. Hoog, Rou-Jia Sung, Aaron E. Engelhart
Publikováno v:
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular BiologyREFERENCES. 48(5)
Structural biology education commonly employs molecular visualization software, such as PyMol, RasMol, and VMD, to allow students to appreciate structure-function relationships in biomolecules. In on-ground, classroom-based education, these programs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690a208db991f818a56cee0e643248fa
https://pubmed.ncbi.nlm.nih.gov/32604463
https://pubmed.ncbi.nlm.nih.gov/32604463
Autor:
Nathaniel J. Gaut, Aaron E. Engelhart, Lauren M. Aufdembrink, Katarzyna P. Adamala, Pavana Khan
Publikováno v:
RNA
Isothermal, cell-free, synthetic biology-based approaches to pathogen detection leverage the power of tools available in biological systems, such as highly active polymerases compatible with lyophilization, without the complexity inherent to live-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d7099e68fd0d73ad33935166ca46b9
Autor:
Aaron E. Engelhart, Brent A. Heffron, Katarzyna P. Adamala, Jose Gomez-Garcia, Erin E. Carlson, B. Cash, Nathaniel J. Gaut, Lauren M. Aufdembrink, Joshua D. Shirley, Joseph M. Heili
Publikováno v:
Journal of Chemical Education. 95:1867-1871
A teaching laboratory experiment is described where students prepare in vitro transcription reactions of a fluorescent RNA aptamer, named Broccoli, and observe the production of the aptamer in real...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0965efeff093aec168f423a2a6895d6
https://doi.org/10.1021/acs.jchemed.7b00735
https://doi.org/10.1021/acs.jchemed.7b00735
Autor:
Lauren M, Aufdembrink, Tanner G, Hoog, Matthew R, Pawlak, Benjamin F, Bachan, Joseph M, Heili, Aaron E, Engelhart
Publikováno v:
Methods in enzymology. 623
Thermal denaturation is a common technique in the biophysical study of nucleic acids. These experiments are typically performed by monitoring the increase in absorbance (hyperchromism) of a sample at 260nm with temperature (MergnyLacroix, 2003; Pugli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9875d1a260cbd4b7fa995b3c67877e64
https://pubmed.ncbi.nlm.nih.gov/31239049
https://pubmed.ncbi.nlm.nih.gov/31239049
Autor:
Tanner G. Hoog, Aaron E. Engelhart, Benjamin F. Bachan, Joseph M. Heili, Lauren M. Aufdembrink, Matthew R. Pawlak
Thermal denaturation is a common technique in the biophysical study of nucleic acids. These experiments are typically performed by monitoring the increase in absorbance (hyperchromism) of a sample at 260nm with temperature (Mergny & Lacroix, 2003; Pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46b1209c1acd5fe54239db7fb7fcdad8
https://doi.org/10.1016/bs.mie.2019.05.029
https://doi.org/10.1016/bs.mie.2019.05.029