Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lauren M. Adams"'
Autor:
Lauren M. Adams, Caroline J. DeHart, Bryon S. Drown, Lissa C. Anderson, William Bocik, Emily S. Boja, Tara M. Hiltke, Christopher L. Hendrickson, Henry Rodriguez, Michael Caldwell, Reza Vafabakhsh, Neil L. Kelleher
Publikováno v:
The Journal of biological chemistry. 299(1)
The KRAS gene is one of the most frequently mutated oncogenes in human cancer and gives rise to two isoforms, KRAS4A and KRAS4B. KRAS post-translational modifications (PTMs) have the potential to influence downstream signaling. However, the relations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7083ab8b0cc92583f0e0a81a43bf552
https://pubmed.ncbi.nlm.nih.gov/36470426
https://pubmed.ncbi.nlm.nih.gov/36470426
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611890
Methods Mol Biol
Methods Mol Biol
The characterization of biologically relevant post-translational modifications (PTMs) on KRAS4B has historically been carried out through methodologies such as immunoblotting with PTM-specific antibodies or peptide-based proteomic methods. While thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f9c01d5ec45a1de3f7720107ed64c0
https://doi.org/10.1007/978-1-0716-1190-6_3
https://doi.org/10.1007/978-1-0716-1190-6_3
Autor:
Steven M. Patrie, Alexander S. Lee, Lauren M. Adams, Ashley N. Ives, Henrique S. Seckler, Luis F. Schachner, Neil L. Kelleher, John P. McGee, Denise P Tran, Erika N. Cline, Kenneth R. Durbin, Rafael D. Melani, Benjamin J. Des Soye, Kevin Jooss
Publikováno v:
Int J Mass Spectrom
The combined use of electrospray ionization run in so-called "native mode" with top-down mass spectrometry (nTDMS) is enhancing both structural biology and discovery proteomics by providing three levels of information in a single experiment: the inta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8636764695c53c1634f101b5b14d17fc
https://doi.org/10.1016/j.ijms.2021.116591
https://doi.org/10.1016/j.ijms.2021.116591
Autor:
Christopher L. Hendrickson, Neil L. Kelleher, Lissa C. Anderson, Luca Fornelli, Lauren M. Adams, Caroline J. DeHart
Publikováno v:
Molecular Cancer Research. 18:A26-A26
The two KRAS isoforms, 4A and 4B, exhibit high sequence identity, differing mainly in their C-terminal “hypervariable regions”, which bear post-translational modifications (PTMs) governing their association with the plasma membrane and downstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfeffb8d090cbdf760673bf9c907287d
https://doi.org/10.1158/1557-3125.ras18-a26
https://doi.org/10.1158/1557-3125.ras18-a26