Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lauren M Slosky"'
Autor:
Graydon B. Gereau, Diana Zhou, Kalynn Van Voorhies, Ryan E. Tyler, Jeffrey Campbell, Jackson G. Murray, Ali Alvarez-Pamir, Luke A. Wykoff, Michel A. Companion, Michael R. Jackson, Steven H. Olson, Lawrence S. Barak, Lauren M. Slosky, Ryan P. Vetreno, Joyce Besheer, Zoe A. McElligott
Publikováno v:
Addiction Neuroscience, Vol 13, Iss , Pp 100185- (2024)
Alcohol use disorders (AUDs) impose an enormous societal and financial burden, and world-wide, alcohol misuse is the 7th leading cause of premature death [1]. Despite this, there are currently only 3 FDA approved pharmacological approaches for the tr
Externí odkaz:
https://doaj.org/article/d94961354bbf425ea2efeab23e05c46e
Autor:
Lucy Sanchez-Covarrubias, Lauren M Slosky, Brandon J Thompson, Yifeng Zhang, Mei-Li Laracuente, Kristin M DeMarco, Patrick T Ronaldson, Thomas P Davis
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88516 (2014)
Our laboratory has previously demonstrated that peripheral inflammatory pain (PIP), induced by subcutaneous plantar injection of λ-carrageenan, results in increased expression and activity of the ATP-dependent efflux transporter P-glycoprotein (P-gp
Externí odkaz:
https://doaj.org/article/fd44c9292b344d9f9cf6f3bbff866d47
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/026e4b553f4144019a1b103dda3cce3f
Autor:
Lauren M. Slosky, Andrea Pires, Yushi Bai, Nicholas B. Clark, Elizabeth R. Hauser, Joshua D. Gross, Fiona Porkka, Yang Zhou, Xiaoxiao Chen, Vladimir M. Pogorelov, Krisztian Toth, William C. Wetsel, Lawrence S. Barak, Marc G. Caron
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Genetically tractable animal models provide needed strategies to resolve the biological basis of drug addiction. Intravenous self-administration (IVSA) is the gold standard for modeling psychostimulant and opioid addiction in animals, but te
Externí odkaz:
https://doaj.org/article/7c675227d5794bc9859b41246a97e78c
Autor:
Brian E. Krumm, Jeffrey F. DiBerto, Reid H. J. Olsen, Hye Jin Kang, Samuel T. Slocum, Shicheng Zhang, Ryan T. Strachan, Xi-Ping Huang, Lauren M. Slosky, Anthony B. Pinkerton, Lawrence S. Barak, Marc G. Caron, Terry Kenakin, Jonathan F. Fay, Bryan L. Roth
Publikováno v:
Biochemistry. 62:1233-1248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e46ba96106037966aa36314ed803bd6d
https://doi.org/10.1021/acs.biochem.3c00029
https://doi.org/10.1021/acs.biochem.3c00029
Autor:
Brian E. Krumm, Jeffrey F. DiBerto, Reid H. J. Olsen, Hye Jin Kang, Samuel T. Slocum, Shicheng Zhang, Ryan T. Strachan, Lauren M. Slosky, Anthony B. Pinkerton, Lawrence S. Barak, Marc G. Caron, Terry Kenakin, Jonathan F. Fay, Bryan L. Roth
SUMMARYThe NTSR1 neurotensin receptor (NTSR1) is a G protein coupled receptor (GPCR) found in the brain and peripheral tissues with neurotensin (NTS) being its endogenous peptide ligand. In the brain, NTS modulates dopamine neuronal activity, induces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7f8f9a1b8e405f18eeb9bd5e4602a8f
https://doi.org/10.1101/2022.12.26.521971
https://doi.org/10.1101/2022.12.26.521971
Autor:
Sarthak M. Singhal, Vivien Zell, Lauren Faget, Lauren M. Slosky, Lawrence S. Barak, Marc G. Caron, Anthony B. Pinkerton, Thomas S. Hnasko
Publikováno v:
Neuropharmacology. 234:109544
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0a306cb68ce0cf1163bff88ecae7890
https://doi.org/10.1016/j.neuropharm.2023.109544
https://doi.org/10.1016/j.neuropharm.2023.109544
Autor:
Kathryn J. Hornburg, Lauren M. Slosky, Gary Cofer, James Cook, Yi Qi, Fiona Porkka, Nicholas B. Clark, Andrea Pires, Jeffrey R. Petrella, Leonard E. White, William C. Wetsel, Lawrence Barak, Marc G. Caron, G. Allan Johnson
Publikováno v:
NMR in biomedicineREFERENCES.
The United States is experiencing a dramatic increase in maternal opioid misuse and, consequently, the number of individuals exposed to opioids in utero. Prenatal opioid exposure has both acute and long-lasting effects on health and wellbeing. Effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee73e1c5111664f0ea0176f5c216b35
https://pubmed.ncbi.nlm.nih.gov/36259728
https://pubmed.ncbi.nlm.nih.gov/36259728
Publikováno v:
Trends Pharmacol Sci
G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors in the genome and the most successful family of targets of FDA-approved drugs. New frontiers in GPCR drug discovery remain, however, as achieving receptor subtype sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2c9c9e13d6b015c584af2f96b7d7ae
https://doi.org/10.1016/j.tips.2020.12.005
https://doi.org/10.1016/j.tips.2020.12.005
Autor:
Layton H. Smith, Michael R. Jackson, Bekhi Falter, Larry S. Barak, Fusayo Yamamoto, Robert Ardecky, Yushi Bai, Anthony B. Pinkerton, Lauren M. Slosky, Paul Hershberger, Michael P Hedrick, Patrick R. Maloney, Satyamaheshwar Peddibhotla, Marc G. Caron, Thomas D.Y. Chung
Publikováno v:
J Med Chem
Neurotensin receptor 1 (NTR1) is a G protein coupled receptor that is widely expressed throughout the central nervous system where it acts as a neuromodulator. Neurotensin receptors have been implicated in a wide variety of CNS disorders, but despite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61914fbb8af999870ab0bf6398673b6
https://doi.org/10.1021/acs.jmedchem.9b00340
https://doi.org/10.1021/acs.jmedchem.9b00340