Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lauren M Saunders"'
Autor:
Andrew J Aman, Lauren M Saunders, August A Carr, Sanjay Srivatasan, Colten Eberhard, Blake Carrington, Dawn Watkins-Chow, William J Pavan, Cole Trapnell, David M Parichy
Publikováno v:
eLife, Vol 12 (2023)
Pigment patterns and skin appendages are prominent features of vertebrate skin. In zebrafish, regularly patterned pigment stripes and an array of calcified scales form simultaneously in the skin during post-embryonic development. Understanding the me
Externí odkaz:
https://doaj.org/article/0404da2852a442729dc8e111e624a00c
Autor:
Tuo Shi, Marielle O Beaulieu, Lauren M Saunders, Peter Fabian, Cole Trapnell, Neil Segil, J Gage Crump, David W Raible
Publikováno v:
eLife, Vol 12 (2023)
A major cause of human deafness and vestibular dysfunction is permanent loss of the mechanosensory hair cells of the inner ear. In non-mammalian vertebrates such as zebrafish, regeneration of missing hair cells can occur throughout life. While a comp
Externí odkaz:
https://doaj.org/article/453e461ae07245579ef96440d47eaab7
Autor:
Anneke Dixie Kakebeen, Alexander Daniel Chitsazan, Madison Corinne Williams, Lauren M Saunders, Andrea Elizabeth Wills
Publikováno v:
eLife, Vol 9 (2020)
Vertebrate appendage regeneration requires precisely coordinated remodeling of the transcriptional landscape to enable the growth and differentiation of new tissue, a process executed over multiple days and across dozens of cell types. The heterogene
Externí odkaz:
https://doaj.org/article/afdf7b8710164a5794a7ff14ff8d7902
Autor:
Lauren M Saunders, Abhishek K Mishra, Andrew J Aman, Victor M Lewis, Matthew B Toomey, Jonathan S Packer, Xiaojie Qiu, Jose L McFaline-Figueroa, Joseph C Corbo, Cole Trapnell, David M Parichy
Publikováno v:
eLife, Vol 8 (2019)
Thyroid hormone (TH) regulates diverse developmental events and can drive disparate cellular outcomes. In zebrafish, TH has opposite effects on neural crest derived pigment cells of the adult stripe pattern, limiting melanophore population expansion,
Externí odkaz:
https://doaj.org/article/d802aca4e8474f9799616ec7022d2e47
Autor:
Jasper Panten, Stefania Del Prete, James P. Cleland, Lauren M. Saunders, Job van Riet, Anja Schneider, Paul Ginno, Nina Schneider, Marie-Luise Koch, Xuqi Chen, Moritz Gerstung, Oliver Stegle, Arthur P. Arnold, James M. A. Turner, Edith Heard, Duncan T. Odom
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract The Four Core Genotypes (FCG) is a mouse model system used to disentangle the function of sex chromosomes and hormones. We report that a copy of a 3.2 MB region of the X chromosome has translocated to the Y Sry- chromosome and thus increased
Externí odkaz:
https://doaj.org/article/aac4a1679e0d4f16ba7dcb7ac9ca1865
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Dimensionality reduction is often used to visualize expression profiling data in order to find relationships among cells. Here, the authors use Uniform Manifold Approximation and Projection (UMAP) on published expression data of gene deletions of S.
Externí odkaz:
https://doaj.org/article/a0311ead30404d9aa682e166ed1e7d83
Autor:
Andrew J. Aman, Lauren M. Saunders, August A. Carr, Sanjay R. Srivatsan, Colten D. Eberhard, Blake Carrington, Dawn Watkins-Chow, William J. Pavan, Cole Trapnell, David M. Parichy
Pigment patterns and skin appendages are prominent features of vertebrate skin. In zebrafish, regularly patterned pigment stripes and an array of calcified scales form simultaneously in the skin during post-embryonic development. Understanding mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd61bc242e9a8cb09d17d95b2b8d884a
https://doi.org/10.7554/elife.86670.1
https://doi.org/10.7554/elife.86670.1
Autor:
Kevin P. Mouillesseaux, David S. Wiley, Lauren M. Saunders, Lyndsay A. Wylie, Erich J. Kushner, Diana C. Chong, Kathryn M. Citrin, Andrew T. Barber, Youngsook Park, Jun-Dae Kim, Leigh Ann Samsa, Jongmin Kim, Jiandong Liu, Suk-Won Jin, Victoria L. Bautch
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The mechanism underlying endothelial cell responses to BMP signals is unknown. Here, the authors show that the endothelial response to pro-angiogenic BMP ligands is regulated by Notch via its effect on SMAD6, a known inhibitor of BMP intracellular si
Externí odkaz:
https://doaj.org/article/44b4ac900f6945ee9370e7b87a8009d9
Autor:
Marielle O Beaulieu, Tuo Shi, Lauren M Saunders, Peter Fabian, Cole Trapnell, Neil Segil, J Gage Crump, David W Raible
Publikováno v:
eLife. 12
A major cause of human deafness and vestibular dysfunction is permanent loss of the mechanosensory hair cells of the inner ear. In non-mammalian vertebrates such as zebrafish, regeneration of missing hair cells can occur throughout life. While a comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc454c12d3bd066afc42c13941136b6f
https://pubmed.ncbi.nlm.nih.gov/36598134
https://pubmed.ncbi.nlm.nih.gov/36598134