Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lauren K. Hughes"'
Autor:
Vasily Giannakeas, Amanda Smith, Hong Wang, Harriet Feilotter, Melyssa Aronson, Andrea Eisen, Raymond H Kim, Jordan Lerner-Ellis, Steven A Narod, Laszlo Radvanyi, Kathleen Bell, Jane Bayani, Ian King, DAVID MALKIN, Kathy Chun, Irene L Andrulis, Bailey Gallinger, Anita Villani, George Charames, Lincoln Stein, Sarah Sawyer, Karen Panabaker, Philip Awadalla, Trevor Pugh, Mohammad Reza Akbari, Peter Goodhand, Brandon Chan, Yael Silberman, Jennifer Brooks, Melanie Spears, Kirsten M Farncombe, Lauren K Hughes, Elif Tuzlali, Michelle D Brazas, Melissa Cable-Cibula, Melanie Courtot, Jamie Harland, Katie Lark, Ellen MacDougall, Alison Rusnak, Christopher Deutschman, Chiquita Hessels, Brittney Johnstone, Talia Mancuso, Kelly McDonald, Meredith McLaren, Karen Ott, Stephen Parrott, Wendy Parulekar, Aaron Pollet, Laila Schenkel, Larissa Waldman, Martin Yaffe
Publikováno v:
BMJ Open, Vol 14, Iss 11 (2024)
Introduction In Canada, care for individuals with hereditary cancer is fragmented across the provinces and territories, with carriers of pathogenic variants in cancer-susceptibility genes seeing multiple doctors and often advocating for their own man
Externí odkaz:
https://doaj.org/article/5933192ab0ec45c4b3bb3c64b90ddbd6
Autor:
David N. Sheppard, Zhiwei Cai, Filipa Mendes, André Schmidt, Margarida D. Amaral, Lauren K. Hughes, Hongyu Li
Publikováno v:
British Journal of Pharmacology. 153:1311-1323
Background and purpose: Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl− channel. In the search for new CF therapies, small molecules have been identified that rescue the defective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4f9098974548f0069c7b6c456ef65cb
https://doi.org/10.1038/sj.bjp.0707663
https://doi.org/10.1038/sj.bjp.0707663
Publikováno v:
Molecular Membrane Biology. 25:528-538
The chemical solvent tetrahydrofuran (THF) increases short-circuit current (I(sc)) in renal epithelia endogenously expressing the cystic fibrosis transmembrane conductance regulator (CFTR). To understand how THF increases I(sc), we employed the Ussin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ddfd30dfaccb115bc5ab9496a9596a
https://doi.org/10.1080/09687680802487967
https://doi.org/10.1080/09687680802487967
lar an . All r nion Flow Through the CFTR Pore: The MSDs B . R egulation of CFTR Channel Gating by Intracellular ATP: The NBDs C . P hosphorylation‐Dependent Regulation of CFTR: The R Domain III. T he Cellular Physiology of CFTR IV. T he Role of CF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::326b59022fa37943570399bfdc88abd8
https://doi.org/10.1016/s1569-2558(06)38005-8
https://doi.org/10.1016/s1569-2558(06)38005-8
Autor:
Lauren K. Hughes
Publikováno v:
Physiology News. :40-41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab17d3e59635228ff73dbfb00ec95f67
https://doi.org/10.36866/pn.87.40
https://doi.org/10.36866/pn.87.40
Autor:
Mohabir Ramjeesingh, David N. Sheppard, Céline Auzanneau, Renaud Dérand, Christine E. Bear, Caroline Norez, Canhui Li, Lauren K. Hughes, Ilana Kogan, Laurence Bulteau-Pignoux, John R. Riordan, Hongyu Li, Frédéric Becq, Ghanshyam D. Heda, Timothy J. Jensen
Publikováno v:
Journal of Cystic Fibrosis. :119-121
Flux studies using either radioisotopes or ion-selective electrodes are a convenient method to assay the function of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl − channel. Here, we described three different protocols to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b3634b584e2340f4a3987c3bad35a2