Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lauren K. Heine"'
Autor:
Lauren K. Heine, Lichchavi D. Rajasinghe, James G. Wagner, Ryan P. Lewandowski, Quan-Zhen Li, Alexa L. Richardson, Ashleigh N. Tindle, Jenan J. Shareef, Jack R. Harkema, James J. Pestka
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
Lupus, a systemic autoimmune disease shaped by gene-environment interplay, often progresses to endstage renal failure. While subchronic systemic exposure to bacterial lipopolysaccharide (LPS) triggers autoimmunity and glomerulonephritis in lupus-pron
Externí odkaz:
https://doaj.org/article/24dd03243e4e46369e01de89b45b93c9
Autor:
Olivia K. Favor, Preeti S. Chauhan, Elham Pourmand, Angel M. Edwards, James G. Wagner, Ryan P. Lewandowski, Lauren K. Heine, Jack R. Harkema, Kin Sing Stephen Lee, James J. Pestka
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionLipopolysaccharide (LPS)-accelerated autoimmune glomerulonephritis (GN) in NZBWF1 mice is a preclinical model potentially applicable for investigating lipidome-modulating interventions against lupus. LPS can be expressed as one of two che
Externí odkaz:
https://doaj.org/article/833e51e1555d4f3481899efdb941de51
Autor:
Lauren K. Heine, Abby D. Benninghoff, Elizabeth A. Ross, Lichchavi D. Rajasinghe, James G. Wagner, Ryan P. Lewandowski, Alexa L. Richardson, Quan-Zhen Li, John P. Buchweitz, Justin Zyskowski, Ashleigh N. Tindle, Anna E. Skedel, Nicholas J. Chargo, Laura R. McCabe, Jack R. Harkema, James J. Pestka
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Autoimmune diseases can be triggered by environmental toxicants such as crystalline silica dust (cSiO2). Here, we characterized the dose-dependent immunomodulation and toxicity of the glucocorticoid (GC) prednisone in a preclinical model that emulate
Externí odkaz:
https://doaj.org/article/9d62c3f710e94b838f4b340305d3c650
Autor:
Susan C. Tilton, Lauren K. Heine, Lisbeth K. Siddens, Kay A. Fischer, Christiane V. Löhr, David A. Sampson, Zhen Yu, Yvonne Chang
Publikováno v:
Toxicol Appl Pharmacol
Current assumption for assessing carcinogenic risk of polycyclic aromatic hydrocarbons (PAHs) is that they function through a common mechanism of action; however, recent studies demonstrate that PAHs can act through unique mechanisms potentially cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f3858aa3911aff0daa877c49fcee0f
https://pubmed.ncbi.nlm.nih.gov/31255691
https://pubmed.ncbi.nlm.nih.gov/31255691
Autor:
Ryan P. Lewandowski, Jack R. Harkema, Lauren K. Heine, Kathryn A. Wierenga, James J. Pestka, Preeti S. Chauhan
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc7b7af52d8132f816cd23ede1216813
https://doi.org/10.1096/fasebj.2020.34.s1.07030
https://doi.org/10.1096/fasebj.2020.34.s1.07030