Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lauren K. Albacarys"'
Autor:
Chenglai Fu, Tomas Rojas, Alfred C. Chin, Weiwei Cheng, Isaac A. Bernstein, Lauren K. Albacarys, William W. Wright, Solomon H. Snyder
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires
Externí odkaz:
https://doaj.org/article/f739f70dc2034291be1474b5f19655c4
Autor:
Chirag Vasavda, Risheng Xu, Jason Liew, Ruchita Kothari, Ryan S. Dhindsa, Evan R. Semenza, Bindu D. Paul, Dustin P. Green, Mark F. Sabbagh, Joseph Y. Shin, Wuyang Yang, Adele M. Snowman, Lauren K. Albacarys, Abhay Moghekar, Carlos A. Pardo-Villamizar, Mark Luciano, Judy Huang, Chetan Bettegowda, Shawn G. Kwatra, Xinzhong Dong, Michael Lim, Solomon H. Snyder
Publikováno v:
Science advances. 8(31)
Trigeminal neuralgia, historically dubbed the “suicide disease,” is an exceedingly painful neurologic condition characterized by sudden episodes of intense facial pain. Unfortunately, the only U.S. Food and Drug Administration (FDA)–approved me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cabc7afd9518e36431b9f1a2ca7cad5
https://pubmed.ncbi.nlm.nih.gov/35921423
https://pubmed.ncbi.nlm.nih.gov/35921423
Publikováno v:
Proc Natl Acad Sci U S A
Inositol hexakisphosphate kinases (IP6Ks) regulate various biological processes. IP6Ks convert IP6 to pyrophosphates such as diphosphoinositol pentakisphosphate (IP7) and bis-diphosphoinositol tetrakisphosphate (IP8). IP7 is produced in mammals by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361905017fda8c93dce46420903aeef2
https://doi.org/10.1073/pnas.2020695118
https://doi.org/10.1073/pnas.2020695118
Autor:
Timothy West, Robin Roychaudhuri, Moataz M. Gadalla, Mario L Amzel, Harry Saavedra, Solomon H. Snyder, Lauren K. Albacarys
Publikováno v:
SSRN Electronic Journal.
Endogenous D-stereoisomers of amino acids are poorly understood in mammals. Here we report the identification and function of endogenous D-cysteine in the pancreas. D-cysteine is present in substantial amounts in the eyes and pancreas of mice. Serine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfc8856b7c2dab14ffc662ef44a65b44
https://doi.org/10.2139/ssrn.3908781
https://doi.org/10.2139/ssrn.3908781
Autor:
Chirag Vasavda, Lauren K. Albacarys, Ruchita Kothari, Evan R. Semenza, Robert Tokhunts, Jason Liew, Solomon H. Snyder, Adele M. Snowman, Cristina Ricco, Shruthi Shanmukha, Bindu D. Paul, Ryan S. Dhindsa
Synapses are complex bridges that connect discrete neurons into vast networks that send, receive, and encode diverse forms of information. However, they must remain dynamic in order to adapt to changing inputs. Here, we report that the enzyme biliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::026623c054097ba912bf2681fd2148e1
https://doi.org/10.1101/2020.12.01.405720
https://doi.org/10.1101/2020.12.01.405720
Autor:
Tomas Rojas, Alfred C. Chin, Chenglai Fu, Lauren K. Albacarys, Isaac A. Bernstein, William W. Wright, Solomon H. Snyder, Weiwei Cheng
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Inositol hexakisphosphate kinase-1 (IP6K1) is required for male fertility, but the underlying mechanisms have been elusive. Here, we report that IP6K1 is required for multiple aspects of male germ cell development. This development requires selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39ac4e2302e11feafdd49733171fe7e
https://doaj.org/article/f739f70dc2034291be1474b5f19655c4
https://doaj.org/article/f739f70dc2034291be1474b5f19655c4
Autor:
Anthony Lin, Adarsha P. Malla, Cristina Ricco, Bindu D. Paul, Risheng Xu, Chirag Vasavda, Harry Saavedra, Lauren K. Albacarys, Ming Ji, Ruchita Kothari, Robert Tokhunts, Lynda D. Hester, Juan I. Sbodio, Solomon H. Snyder, Thomas W. Sedlak, Adele M. Snowman
Publikováno v:
Cell Chemical Biology. 26:1450-1460.e7
Summary Bilirubin is one of the most frequently measured metabolites in medicine, yet its physiologic roles remain unclear. Bilirubin can act as an antioxidant in vitro, but whether its redox activity is physiologically relevant is unclear because ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb2915e9bda924c5eed90ded5347ffb
https://doi.org/10.1016/j.chembiol.2019.07.006
https://doi.org/10.1016/j.chembiol.2019.07.006
Autor:
Richa Tyagi, Bindu D. Paul, Maimon E. Hubbi, Lauren K. Albacarys, Jonathan C. Grima, Seyun Kim, Solomon H. Snyder, Juan I. Sbodio, Ishrat Ahmed, Maged M. Harraz, Risheng Xu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(31)
Huntington’s disease (HD) is a progressive neurodegenerative disease caused by a glutamine repeat expansion in mutant huntingtin (mHtt). Despite the known genetic cause of HD, the pathophysiology of this disease remains to be elucidated. Inositol p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8b15fb3464ac4bf89221cdc09bbce3
https://pubmed.ncbi.nlm.nih.gov/26195796
https://pubmed.ncbi.nlm.nih.gov/26195796