Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Lauren J Mills"'
Autor:
Rachel M Moss, Kelsie Becklin, Lauren J Mills, Branden S Moriarity, Beau R Webber, Logan G Spector
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 77-78 (2023)
OBJECTIVES/GOALS: We leverage the disparate incidence of Ewing sarcoma (ES) between European (EUR) and African (AFR) ancestry to study ES tumorigenesis in iPSC-derived cells from donors with a range of AFR ancestry via functional / molecular profilin
Externí odkaz:
https://doaj.org/article/e60b25c03477485fb436fb3c51435368
Autor:
Alessandro Magli, June Baik, Lauren J Mills, Il-Youp Kwak, Bridget S Dillon, Ricardo Mondragon Gonzalez, David A Stafford, Scott A Swanson, Ron Stewart, James A Thomson, Daniel J Garry, Brian D Dynlacht, Rita C R Perlingeiro
Publikováno v:
PLoS Biology, Vol 17, Iss 2, p e3000153 (2019)
The transcriptional mechanisms driving lineage specification during development are still largely unknown, as the interplay of multiple transcription factors makes it difficult to dissect these molecular events. Using a cell-based differentiation pla
Externí odkaz:
https://doaj.org/article/09304123793a415cb5a26e79fc1ee488
Publikováno v:
HGG Advances, Vol 6, Iss 1, Pp 100356- (2025)
Summary: The aim of this study was to scan phenotypes in adulthood associated with polygenic risk scores (PRS) for childhood cancers with well-articulated genetic architectures—acute lymphoblastic leukemia (ALL), Ewing sarcoma, and neuroblastoma—
Externí odkaz:
https://doaj.org/article/38252937d2704fa6bbf4545737fd5751
Autor:
Aaron L. Sarver, Lauren J. Mills, Kelly M. Makielski, Nuri A. Temiz, Jinhua Wang, Logan G. Spector, Subbaya Subramanian, Jaime F. Modiano
Publikováno v:
Cancer Genetics. :1-11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ce3c99a00cc28e908fec151a0d8adaa
https://doi.org/10.1016/j.cancergen.2023.05.001
https://doi.org/10.1016/j.cancergen.2023.05.001
Autor:
Kelly M. Makielski, Aaron L. Sarver, Michael S. Henson, Kathleen M. Stuebner, Antonella Borgatti, Lukkana Suksanpaisan, Caitlin Preusser, Alexandru-Flaviu Tabaran, Ingrid Cornax, M. Gerard O’Sullivan, Andrea Chehadeh, Donna Groschen, Kelly Bergsrud, Sara Pracht, Amber Winter, Lauren J. Mills, Marc D. Schwabenlander, Melissa Wolfe, Michael A. Farrar, Gary R. Cutter, Joseph S. Koopmeiners, Stephen J. Russell, Jaime F. Modiano, Shruthi Naik
Publikováno v:
bioRxiv
VSV-IFNβ-NIS is a recombinant oncolytic vesicular stomatitis virus (VSV) that is being evaluated clinically for the treatment of advanced malignancies. As with other cancer immunotherapies, identifying biomarkers of response will be critical to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c7479aafb74daf0df9b4d7bd0ee63e
https://europepmc.org/articles/PMC10153185/
https://europepmc.org/articles/PMC10153185/
Autor:
Branden S. Moriarity, David A. Largaespada, Eric P. Rahrmann, Wendy A. Hudson, Margaret R. Crosby, Lauren J. Mills, Susan K. Rathe, Juan E. Abrahante, Joseph J. Peterson, Kanut Laoharawee, Kyle B. Williams, Kenta Yamamoto, Kelsie L. Becklin, Emily J. Pomeroy, Natalie Stratton, Alex T. Larsson, Nicholas J. Slipek, Garrett M. Draper, Branden A. Smeester
Supplementary data for Smeester et al.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1926e61d461be2c0d40bf83b6375393d
https://doi.org/10.1158/1535-7163.22521444.v1
https://doi.org/10.1158/1535-7163.22521444.v1
Autor:
Branden S. Moriarity, David A. Largaespada, Eric P. Rahrmann, Wendy A. Hudson, Margaret R. Crosby, Lauren J. Mills, Susan K. Rathe, Juan E. Abrahante, Joseph J. Peterson, Kanut Laoharawee, Kyle B. Williams, Kenta Yamamoto, Kelsie L. Becklin, Emily J. Pomeroy, Natalie Stratton, Alex T. Larsson, Nicholas J. Slipek, Garrett M. Draper, Branden A. Smeester
List of all DEGs identified in transient ZNF217 knockdown versus control SJSA-1 OSA cells with associated fold changes and FDR-adjusted p values.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7498558170065e3b7ce8a004ecc5954d
https://doi.org/10.1158/1535-7163.22521438
https://doi.org/10.1158/1535-7163.22521438
Autor:
Jenna K. Larson, DeVon N. Hunter‐Schlichting, Erin L. Crowgey, Lauren J. Mills, Todd E. Druley, Erin L. Marcotte
Publikováno v:
Cancer medicineREFERENCES.
The KMT2 family of genes is essential epigenetic regulators promoting gene expression. The gene family contains three subgroups, each with two paralogues: KMT2A and KMT2B; KMT2C and KMT2D; KMT2F and KMT2G. KMT2A-D are among the most frequent somatica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a59b17f1438ece45a810fd21cb5cbcd
https://pubmed.ncbi.nlm.nih.gov/36479909
https://pubmed.ncbi.nlm.nih.gov/36479909
Autor:
Freddy A. Barragan, Lauren J. Mills, Andrew R. Raduski, Erin L. Marcotte, Kelsey E. Grinde, Logan G. Spector, Lindsay A. Williams
Publikováno v:
Cancer medicineREFERENCES.
Black children have lower incidence yet worse survival than White and Latinx children with B-cell acute lymphoblastic leukemia (B-ALL). It is unclear how reported race/ethnicity (RRE) is associated with death in B-ALL after accounting for differentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aff68d6a31f840d119d34773b25d25b
https://pubmed.ncbi.nlm.nih.gov/36127808
https://pubmed.ncbi.nlm.nih.gov/36127808
Autor:
Kyle B. Williams, Lauren J. Mills, David A. Largaespada, Kelsie L. Becklin, Joseph J. Peterson, Nicholas J. Slipek, Garrett M. Draper, Susan K. Rathe, Kenta Yamamoto, Kanut Laoharawee, Emily J. Pomeroy, Natalie Stratton, Juan E. Abrahante, Wendy A. Hudson, Branden S. Moriarity, Margaret R. Crosby, Branden A. Smeester, Eric P. Rahrmann, Alex T. Larsson
Publikováno v:
Mol Cancer Ther
We previously identified ZNF217 as an oncogenic driver of a subset of osteosarcomas using the Sleeping Beauty (SB) transposon system. Here, we followed up by investigating the genetic role of ZNF217 in osteosarcoma initiation and progression through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9425d136e8fb6f10769d6cffc74f37e
https://doi.org/10.1158/1535-7163.mct-20-0369
https://doi.org/10.1158/1535-7163.mct-20-0369