Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lauren J Howson"'
Autor:
Samantha Chan, Benjamin Morgan, Michelle K. Yong, Mai Margetts, Anthony J. Farchione, Erin C. Lucas, Jack Godsell, Nhi Ai Giang, Charlotte A. Slade, Anouk von Borstel, Vanessa L. Bryant, Lauren J. Howson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The function and phenotype of γδ T cells in the context of common variable immunodeficiency (CVID) has not been explored. CVID is a primary immunodeficiency disorder characterized by impaired antibody responses resulting in increased susce
Externí odkaz:
https://doaj.org/article/5b30bc08f2604b69846f6ba0bb2d8815
Autor:
Lauren J. Howson, Vanessa L. Bryant
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/3513781b63ea40d89c23693dfcc225a3
Autor:
Samantha Chan, Jack Godsell, Miles Horton, Anthony Farchione, Lauren J. Howson, Mai Margetts, Celina Jin, Josh Chatelier, Michelle Yong, Joseph Sasadeusz, Jo A. Douglass, Charlotte A. Slade, Vanessa L. Bryant
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundCommon Variable Immunodeficiency (CVID) is classified as a ‘Predominantly Antibody Deficiency’ (PAD), but there is emerging evidence of cellular immunodeficiency in a subset of patients. This evidence includes CVID patients diagnosed wi
Externí odkaz:
https://doaj.org/article/64b1448e1ea24cc0b6641e09ec77c359
Autor:
Anouk von Borstel, Thi HO Nguyen, Louise C Rowntree, Thomas M Ashhurst, Lilith F Allen, Lauren J Howson, Natasha E Holmes, Olivia C Smibert, Jason A Trubiano, Claire L Gordon, Allen C Cheng, Stephen J Kent, Jamie Rossjohn, Katherine Kedzierska, Martin S Davey
Publikováno v:
Immunology & Cell Biology. 101:321-332
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d46b550bee8ee411916ea0feb1372025
https://doi.org/10.1111/imcb.12623
https://doi.org/10.1111/imcb.12623
Autor:
Lauren J. Howson, Giorgio Napolitani, Dawn Shepherd, Hemza Ghadbane, Prathiba Kurupati, Lorena Preciado-Llanes, Margarida Rei, Hazel C. Dobinson, Malick M. Gibani, Karen Wei Weng Teng, Evan W. Newell, Natacha Veerapen, Gurdyal S. Besra, Andrew J. Pollard, Vincenzo Cerundolo
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Most MAIT cell response to infection studies are of mice. Here the authors characterize MAIT cell population responses to Salmonella Paratyphi A infection of 25 human volunteers using TCR clonotype analysis and mass cytometry of pre-infection matched
Externí odkaz:
https://doaj.org/article/09df915b396f40bb884220ebcc1bf9b9
Autor:
Vincenzo Cerundolo, Richard Boyd, Francesca M. Buffa, Stephen Taylor, Lars R. Olsen, Robert L. Strausberg, Qi Zhao, Robert Laynes, Lauren J. Howson, Uzi Gileadi, Dawn Shepherd, Jonathan D. Silk, Hemza Ghadbane, Elina Timosenko
In vivo and in silico analyses of IDO and SLC1A5 expression in primary mouse and human tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1178cf659a9e7515b420d5f3712fdc4b
https://doi.org/10.1158/0008-5472.22411224.v1
https://doi.org/10.1158/0008-5472.22411224.v1
Autor:
Vincenzo Cerundolo, Richard Boyd, Francesca M. Buffa, Stephen Taylor, Lars R. Olsen, Robert L. Strausberg, Qi Zhao, Robert Laynes, Lauren J. Howson, Uzi Gileadi, Dawn Shepherd, Jonathan D. Silk, Hemza Ghadbane, Elina Timosenko
Table S1. Oligonucleotides used for generation of CRISPR guide sequences targeting SLC1A5, ATF4 or LAT1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5dd43e0b07c2c9f7bc0db316789b63
https://doi.org/10.1158/0008-5472.22411215.v1
https://doi.org/10.1158/0008-5472.22411215.v1
Autor:
Vincenzo Cerundolo, Richard Boyd, Francesca M. Buffa, Stephen Taylor, Lars R. Olsen, Robert L. Strausberg, Qi Zhao, Robert Laynes, Lauren J. Howson, Uzi Gileadi, Dawn Shepherd, Jonathan D. Silk, Hemza Ghadbane, Elina Timosenko
Tryptophan degradation is an immune escape strategy shared by many tumors. However, cancer cells' compensatory mechanisms remain unclear. We demonstrate here that a shortage of tryptophan caused by expression of indoleamine 2,3-dioxygenase (IDO) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::207a83018c5a9b58be993ebaa230bb4a
https://doi.org/10.1158/0008-5472.c.6508182.v1
https://doi.org/10.1158/0008-5472.c.6508182.v1
Autor:
Vincenzo Cerundolo, Richard Boyd, Francesca M. Buffa, Stephen Taylor, Lars R. Olsen, Robert L. Strausberg, Qi Zhao, Robert Laynes, Lauren J. Howson, Uzi Gileadi, Dawn Shepherd, Jonathan D. Silk, Hemza Ghadbane, Elina Timosenko
Legends for supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231698403476759f1198a7ea93d3c97c
https://doi.org/10.1158/0008-5472.22411221
https://doi.org/10.1158/0008-5472.22411221
Autor:
Charis E Teh, Hongke Peng, Mengxiao Luo, Tania Tan, Marie Trussart, Lauren J Howson, Chong Chyn Chua, Christine Muttiah, Fiona C Brown, Matthew E Ritchie, Andrew H. Wei, Andrew W Roberts, Vanessa L Bryant, Mary Ann Anderson, Geoffrey J Lindeman, David Ching Siang Huang, Rachel Thijssen, Daniel H D Gray
Publikováno v:
Blood advances.
Venetoclax is an effective treatment for certain blood cancers, such as chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). However, most patients relapse while on venetoclax and further treatment options become limited. Combining ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e29bd2a0c1e33222b6a73009daee16
https://pubmed.ncbi.nlm.nih.gov/36521105
https://pubmed.ncbi.nlm.nih.gov/36521105