Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lauren Holz"'
Autor:
Lauren Holz, Yu Cheng Chua, Regan Anderson, Sarah Draper, Benjamin Compton, Susanna Chan, Juby Mathew, Maria de Menezes, Anton Cozijnsen, Vanessa Mollard, Geoffrey McFadden, Gavin Painter, William R Heath
Publikováno v:
The Journal of Immunology. 204:168.1-168.1
Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vaccines for generating this important immune population are lacking. Here, we report the development of a fully synthetic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40bc2ce6df0db7876f3a9dc03aa4bb97
https://doi.org/10.4049/jimmunol.204.supp.168.1
https://doi.org/10.4049/jimmunol.204.supp.168.1
Publikováno v:
The Journal of Immunology. 194:2280-2288
WC1 proteins are uniquely expressed on γδ T cells and belong to the scavenger receptor cysteine-rich (SRCR) superfamily. While present in variable, and sometimes high, numbers in the genomes of mammals and birds, in cattle there are 13 distinct gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabbc1d69a6fece723b6a2df267fe98f
https://doi.org/10.4049/jimmunol.1402021
https://doi.org/10.4049/jimmunol.1402021
Autor:
Daniel, Fernandez-Ruiz, Lei Shong, Lau, Nazanin, Ghazanfari, Claerwen M, Jones, Wei Yi, Ng, Gayle M, Davey, Dorothee, Berthold, Lauren, Holz, Yu, Kato, Matthias H, Enders, Ganchimeg, Bayarsaikhan, Sanne H, Hendriks, Lianne I M, Lansink, Jessica A, Engel, Megan S F, Soon, Kylie R, James, Anton, Cozijnsen, Vanessa, Mollard, Alessandro D, Uboldi, Christopher J, Tonkin, Tania F, de Koning-Ward, Paul R, Gilson, Tsuneyasu, Kaisho, Ashraful, Haque, Brendan S, Crabb, Francis R, Carbone, Geoffrey I, McFadden, William R, Heath
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(12)
We describe an MHC class II (I-Ab)–restricted TCR transgenic mouse line that produces CD4+ T cells specific for Plasmodium species. This line, termed PbT-II, was derived from a CD4+ T cell hybridoma generated to blood-stage Plasmodium berghei ANKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2514ce39fe0360d049b123acce7b7a5e
https://pubmed.ncbi.nlm.nih.gov/29084838
https://pubmed.ncbi.nlm.nih.gov/29084838
Autor:
Lauren Holz, Yu Cheng Chua, Regan J Anderson, Sarah Draper, Benjamin Compton, Jasmine Li, Lukasz Kedzierski, Zhongfang Wang, Taryn Osmond, Kathryn Farrand, Patrick J Bertolino, David Bowen, Anton Cozijnsen, Vanessa Mollard, Geoffrey McFadden, Irina Caminschi, Mireille Lahoud, Katherine Kedzierska, Stephen John Turner, Dale Godfrey, Ian Hermans, Gavin Painter, William R Heath
Publikováno v:
The Journal of Immunology. 202:196.27-196.27
Liver resident-memory CD8+ T cells (TRM cells) provide important protection against liver-stage Plasmodium infections. Here, we show that a glycolipid-peptide conjugate vaccine designed to be cleaved in vivo to release the NKT cell agonist a-galactos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96d7a3650d2dec69945a90439f4c4eb6
https://doi.org/10.4049/jimmunol.202.supp.196.27
https://doi.org/10.4049/jimmunol.202.supp.196.27
Autor:
David G. Bowen, Monica Zen, Lauren Holz, Thomas Davis, Geoffrey W. McCaughan, Patrick Bertolino
Publikováno v:
Journal of Clinical Investigation. 114:701-712
Hepatic immunobiology is paradoxical: although the liver possesses unusual tolerogenic properties, it is also the site of effective immune responses against multiple pathogens and subject to immune-mediated pathology. The mechanisms underlying this d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0642a904b34a0644c22f8f743a814d
https://doi.org/10.1172/jci200421593
https://doi.org/10.1172/jci200421593
Autor:
Michelle Vo, Lauren Holz, Volker Benseler, Claire McGuffog, Douglas Hilton, Geoffrey McCaughan, David Bowen, Patrick Bertolino
Publikováno v:
The Journal of Immunology. 190:172.14-172.14
Acute hepatitis is often mediated by CD8 T cells that kill target cells or secrete hepatotoxic cytokines. However, the parameters regulating CD8 T cell-mediated acute hepatitis are not well understood. We used the well-characterized Met-Kb Tg mouse m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7054e8c8a551fc929d5a486ef5cff222
https://doi.org/10.4049/jimmunol.190.supp.172.14
https://doi.org/10.4049/jimmunol.190.supp.172.14
Publikováno v:
The Journal of Immunology. 190:49.14-49.14
Chronic hepatitis C virus (HCV) infection results in an inflammatory liver disease leading to fibrosis and cirrhosis. The progression of liver disease is thought to be immune-mediated because HCV itself is non-cytopathic. Given that HCV-specific T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d2e7958a09724436124c85bfe8091ad
https://doi.org/10.4049/jimmunol.190.supp.49.14
https://doi.org/10.4049/jimmunol.190.supp.49.14
Autor:
Patrick Jerome Bertolino, Lauren Holz, Lorraine O’Reilly, Volker Benseler, Geoffrey McCaughan
Publikováno v:
The Journal of Immunology. 178:LB14-LB14
The liver has unique immunological properties. We have proposed that these properties are associated with the unique ability of the hepatic tissue to support primary activation of CD8+ T cells independently of lymphoid tissues. The fate of T cells ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52eeae88f0492f9e48b50d7afdffd9a0
https://doi.org/10.4049/jimmunol.178.supp.b69
https://doi.org/10.4049/jimmunol.178.supp.b69