Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lauren Higgins"'
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9071 (2010)
BACKGROUND: Helicobacter pylori is the etiologic agent of common gastritis and a risk factor for gastric cancer. It is also one of the richest sources of Type II restriction-modification (R-M) systems in microorganisms. PRINCIPAL FINDINGS: We have cl
Externí odkaz:
https://doaj.org/article/23be18e4cc7a4ee684f8909e9bfa6c3f
Autor:
Margaret R. Heider, Jian Sun, Brittany S. Sexton, Bradley W. Langhorst, Andrew Gray, Lauren Higgins, Lixin Chen, Lynne Apone, Thomas C. Evans, Nicole M. Nichols, Pingfang Liu
Publikováno v:
Cancer Research. 83:249-249
In cancer genomics, a common source of DNA is formalin-fixed, paraffin-embedded (FFPE) tissue from patient surgical samples, where in most cases high-quality fresh or frozen tissue samples are not available. FFPE DNA poses many notable challenges for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::997ad09a5fb737cf43dbbb6140001d61
https://doi.org/10.1158/1538-7445.am2023-249
https://doi.org/10.1158/1538-7445.am2023-249
Autor:
Margaret R. Heider, Jian Sun, Brittany S. Sexton, Bradley W. Langhorst, Andrew Gray, Lauren Higgins, Lixin Chen, Lynne Apone, Thomas C. Evans, Nicole M. Nichols, Eileen T. Dimalanta, Theodore B. Davis, Pingfang Liu
Publikováno v:
Cancer Research. 82:5784-5784
In cancer genomics, a common source of DNA is formalin-fixed, paraffin-embedded (FFPE) tissue from patient surgical samples, where in most cases high quality fresh or frozen tissue samples are not available. FFPE DNA poses many notable challenges for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb965d5b607f07692bbbb6a9203c487
https://doi.org/10.1158/1538-7445.am2022-5784
https://doi.org/10.1158/1538-7445.am2022-5784
Publikováno v:
Journal of Burn Care & Research. 42:S80-S80
Introduction Early mobility in intensive care unit (ICU) patients has been demonstrated effective in improving functional status, range of motion, preventing complications, and decreasing length of stay. There is limited data regarding the early mobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b832a4e0a06bdea480da0078ff10bdf0
https://doi.org/10.1093/jbcr/irab032.124
https://doi.org/10.1093/jbcr/irab032.124
Autor:
Nathan McIntosh, Lauren Higgins, Dennis E. Bulman, Christine McRoberts, Pranesh Chakraborty, Svetlana Ogrel, Osama Y. Al-Dirbashi, Michael T. Geraghty, Lawrence Fisher
Publikováno v:
LymphoSign Journal. 2:135-145
Background: Screening newborns for severe combined immunodeficiency (SCID) aims for early identification and treatment of the affected newborns. Adenosine deaminase (ADA) deficiency, a defect in the purine metabolic pathway, is a major cause of SCID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aa92ffc21ddca1d50451c6db671365c
https://doi.org/10.14785/lpsn-2014-0024
https://doi.org/10.14785/lpsn-2014-0024
Autor:
Luo Sun, Margaret R. Heider, Chen Song, Theodore B. Davis, Laurence Ettwiller, Eileen T. Dimalanta, Pingfang Liu, Thomas C. Evans, Lauren Higgins, Lixin Chen
Publikováno v:
Cancer Research. 79:3522-3522
High-throughput sequencing is key for clinical diagnostic applications such as disease mutation profiling and identifying pathogens with high taxonomic specificity. Preparation of high quality next-generation sequencing (NGS) libraries is critical fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f3c3764edd0b6c22d43bc94abaa3f1
https://doi.org/10.1158/1538-7445.am2019-3522
https://doi.org/10.1158/1538-7445.am2019-3522
Autor:
Chen Song, Pingfang Liu, Theodore B. Davis, Thomas C. Evans, Lauren Higgins, Eileen T. Dimalanta, Margaret R. Heider, Laurence Ettwiller, Lixin Chen
Publikováno v:
Cancer Research. 78:1425-1425
Next-generation sequencing (NGS) methods are used extensively to profile mutations present in diseased human tissues. These genomic approaches hold great promise for personalized medicine but sequencing accuracy is essential for proper patient diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a346da67887bf73ed16ce587033eacc
https://doi.org/10.1158/1538-7445.am2018-1425
https://doi.org/10.1158/1538-7445.am2018-1425
Publikováno v:
Protein Engineering Design and Selection. 20:497-504
A cleavage-deficient variant of NotI restriction endonuclease (GCGGCCGC) was isolated by random mutagenesis of the notIR gene. The NotI variant D160N was shown to bind DNA and protect plasmid DNA from EagI (CGGCCG) and NotI digestions. The EDTA-resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73704cac3bd16cdad62c6add4aad3a3
https://doi.org/10.1093/protein/gzm049
https://doi.org/10.1093/protein/gzm049
Publikováno v:
Nucleic Acids Research. 29:2492-2501
N.BstNBI is a nicking endonuclease that recognizes the sequence GAGTC and nicks the top strand preferentially. The Type IIs restriction endonucleases PleI and MlyI also recognize GAGTC, but cleave both DNA strands. Cloning and sequencing the genes en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930bcfdfe192511aa22d3535f952127e
https://doi.org/10.1093/nar/29.12.2492
https://doi.org/10.1093/nar/29.12.2492
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9071 (2010)
PLoS ONE
PLoS ONE
BACKGROUND: Helicobacter pylori is the etiologic agent of common gastritis and a risk factor for gastric cancer. It is also one of the richest sources of Type II restriction-modification (R-M) systems in microorganisms. PRINCIPAL FINDINGS: We have cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d9cd2bdd1d9f1aaee2547300e07cae
http://europepmc.org/articles/PMC2816704?pdf=render
http://europepmc.org/articles/PMC2816704?pdf=render