Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lauren Hartley"'
Autor:
Lauren Hartley, Femi Osukoya
Publikováno v:
BJPsych Open, Vol 10, Pp S105-S106 (2024)
Aims 1)To improve the confidence of the nursing team in ensuring initial assessment and escalation of physical health concerns on an organic old age psychiatry ward, Glade ward, Woodlands unit, RDASH Rotherham. 2)To equip them with the knowledge ne
Externí odkaz:
https://doaj.org/article/1a301851f5fb4f7bbb093e0f0c7e0d90
Autor:
Andrea Loreto, Carlo Angeletti, Weixi Gu, Andrew Osborne, Bart Nieuwenhuis, Jonathan Gilley, Elisa Merlini, Peter Arthur-Farraj, Adolfo Amici, Zhenyao Luo, Lauren Hartley-Tassell, Thomas Ve, Laura M Desrochers, Qi Wang, Bostjan Kobe, Giuseppe Orsomando, Michael P Coleman
Publikováno v:
eLife, Vol 10 (2021)
Axon loss underlies symptom onset and progression in many neurodegenerative disorders. Axon degeneration in injury and disease is promoted by activation of the NAD-consuming enzyme SARM1. Here, we report a novel activator of SARM1, a metabolite of th
Externí odkaz:
https://doaj.org/article/ae90d092381c46bc9faa8cefaa0ea1fc
Autor:
Sarah J Piper, Lou Brillault, Rosalba Rothnagel, Tristan I Croll, Joseph K Box, Irene Chassagnon, Sebastian Scherer, Kenneth N Goldie, Sandra A Jones, Femke Schepers, Lauren Hartley-Tassell, Thomas Ve, Jason N Busby, Julie E Dalziel, J Shaun Lott, Ben Hankamer, Henning Stahlberg, Mark R H Hurst, Michael J Landsberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associate
Externí odkaz:
https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba1
Autor:
Yun Shi, Ibrahim M. El-Deeb, Veronika Masic, Lauren Hartley-Tassell, Andrea Maggioni, Mark von Itzstein, Thomas Ve
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 26 (2021)
Fibrillarin (FBL) is an essential and evolutionarily highly conserved S-adenosyl methionine (SAM) dependent methyltransferase. It is the catalytic component of a multiprotein complex that facilitates 2′-O-methylation of ribosomal RNAs (rRNAs), a mo
Externí odkaz:
https://doaj.org/article/5908c0d993aa46a3976cfecc3d5e31d8
Autor:
David M. P. De Oliveira, Lauren Hartley-Tassell, Arun Everest-Dass, Christopher J. Day, Rebecca A. Dabbs, Thomas Ve, Bostjan Kobe, Victor Nizet, Nicolle H. Packer, Mark J. Walker, Michael P. Jennings, Martina L. Sanderson-Smith
Publikováno v:
mBio, Vol 8, Iss 1 (2017)
ABSTRACT Streptococcus pyogenes (group A streptococcus [GAS]) is responsible for over 500,000 deaths worldwide each year. The highly virulent M1T1 GAS clone is one of the most frequently isolated serotypes from streptococcal pharyngitis and invasive
Externí odkaz:
https://doaj.org/article/a691605b870247b8b88dbc858307280f
Autor:
Mario Waespy, Thaddeus T Gbem, Leroy Elenschneider, André-Philippe Jeck, Christopher J Day, Lauren Hartley-Tassell, Nicolai Bovin, Joe Tiralongo, Thomas Haselhorst, Sørge Kelm
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 12, p e0004344 (2015)
Externí odkaz:
https://doaj.org/article/d648c7dbdf0d40368009276b0e63806d
Autor:
Mario Waespy, Thaddeus T Gbem, Leroy Elenschneider, André-Philippe Jeck, Christopher J Day, Lauren Hartley-Tassell, Nicolai Bovin, Joe Tiralongo, Thomas Haselhorst, Sørge Kelm
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 10, p e0004120 (2015)
Fourteen different active Trypanosoma congolense trans-sialidases (TconTS), 11 variants of TconTS1 besides TconTS2, TconTS3 and TconTS4, have been described. Notably, the specific transfer and sialidase activities of these TconTS differ by orders of
Externí odkaz:
https://doaj.org/article/51c8f3c0673a44b28937d6168d8a6cb2
Autor:
Mohammad K. Manik, Yun Shi, Sulin Li, Mark A. Zaydman, Neha Damaraju, Samuel Eastman, Thomas G. Smith, Weixi Gu, Veronika Masic, Tamim Mosaiab, James S. Weagley, Steven J. Hancock, Eduardo Vasquez, Lauren Hartley-Tassell, Nestoras Kargios, Natsumi Maruta, Bryan Y. J. Lim, Hayden Burdett, Michael J. Landsberg, Mark A. Schembri, Ivan Prokes, Lijiang Song, Murray Grant, Aaron DiAntonio, Jeffrey D. Nanson, Ming Guo, Jeffrey Milbrandt, Thomas Ve, Bostjan Kobe
Publikováno v:
Science (New York, N.Y.). 377(6614)
Cyclic adenosine diphosphate (ADP)–ribose (cADPR) isomers are signaling molecules produced by bacterial and plant Toll/interleukin-1 receptor (TIR) domains via nicotinamide adenine dinucleotide (oxidized form) (NAD + ) hydrolysis. We show that v-cA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b97f099648a037f65223ecc550a0069b
https://pubmed.ncbi.nlm.nih.gov/36048923
https://pubmed.ncbi.nlm.nih.gov/36048923
Autor:
Mohammad K. Manik, Yun Shi, Sulin Li, Mark A. Zaydman, Neha Damaraju, Samuel Eastman, Thomas G. Smith, Weixi Gu, Veronika Masic, Tamim Mosaiab, James S. Weagley, Steven J. Hancock, Eduardo Vasquez, Lauren Hartley-Tassell, Natsumi Maruta, Bryan Y. J. Lim, Hayden Burdett, Michael J. Lansdberg, Mark A. Schembri, Ivan Prokes, Lijiang Song, Murray Grant, Aaron DiAntonio, Jeffrey D. Nanson, Ming Guo, Jeffrey Milbrandt, Thomas Ve, Bostjan Kobe
Cyclic ADP ribose (cADPR) isomers are important signaling molecules produced by bacterial and plant Toll/interleukin-1 receptor (TIR) domains via NAD+ hydrolysis, yet their chemical structures are unknown. We show that v-cADPR (2’cADPR) and v2-cADP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb91a6ed2fc24e49f5ddcc0ff8b6a0f7
https://doi.org/10.1101/2022.05.07.491051
https://doi.org/10.1101/2022.05.07.491051
Autor:
Carlo Angeletti, Andrea Loreto, Weixi Gu, Andrew Osborne, Bart Nieuwenhuis, Jonathan Gilley, Elisa Merlini, Peter Arthur-Farraj, Adolfo Amici, Zhenyao Luo, Lauren Hartley-Tassell, Thomas Ve, Laura M Desrochers, Qi Wang, Bostjan Kobe, Giuseppe Orsomando, Michael P Coleman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cbc54bb5a450eb092b3d84707aae14f
https://doi.org/10.7554/elife.72823.sa2
https://doi.org/10.7554/elife.72823.sa2