Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lauren Harlow"'
Autor:
Carlos A. Toro, Rita De Gasperi, Katherine Vanselow, Lauren Harlow, Kaitlin Johnson, Abdurrahman Aslan, William A. Bauman, Christopher P. Cardozo, Zachary A. Graham
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Traumatic spinal cord injury (SCI) results in the disruption of physiological systems below the level of the spinal lesion. Connexin hemichannels (CxHCs) are membrane-bound, non-selective pore proteins that are lost in mature myofibers but reappear d
Externí odkaz:
https://doaj.org/article/91e5e650b69b49fd9ba9378f869e5e6f
Autor:
Carlos A. Toro, Rita De Gasperi, Abdurrahman Aslan, Nicholas Johnson, Mustafa M. Siddiq, Christine Chow, Wei Zhao, Lauren Harlow, Zachary Graham, Xin-Hua Liu, Junichi Sadoshima, Ravi Iyengar, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 5, Iss 1, Pp 304-316 (2024)
Spinal cord injury (SCI) results in severe atrophy of skeletal muscle in paralyzed regions, and a decrease in the force generated by muscle per unit of cross-sectional area. Oxidation of skeletal muscle ryanodine 1 receptors (RyR1) reduces contractil
Externí odkaz:
https://doaj.org/article/c72386503aab4c5bbf2afb087a682fe8
Autor:
Mustafa M. Siddiq, Carlos A. Toro, Nicholas P. Johnson, Jens Hansen, Yuguang Xiong, Wilfredo Mellado, Rosa E. Tolentino, Kaitlin Johnson, Gomathi Jayaraman, Zaara Suhail, Lauren Harlow, Jinye Dai, Kristin G. Beaumont, Robert Sebra, Dianna E. Willis, Christopher P. Cardozo, Ravi Iyengar
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionNeurons transport mRNA and translational machinery to axons for local translation. After spinal cord injury (SCI), de novo translation is assumed to enable neurorepair. Knowledge of the identity of axonal mRNAs that participate in neurore
Externí odkaz:
https://doaj.org/article/e7907528427c4cc4850262c458caa737
Autor:
Zachary A. Graham, Xin-hua Liu, Lauren Harlow, Jiangping Pan, Daniella Azulai, Hesham A. Tawfeek, Russell D. Wnek, Alex J. Mattingly, William A. Bauman, Joshua F. Yarrow, Christopher P. Cardozo
Publikováno v:
Neurotrauma Reports, Vol 1, Iss 1, Pp 17-31 (2020)
Spinal cord injury (SCI) is associated with obesity and is a risk factor for type 2 diabetes mellitus (T2DM). Immobilization, muscle atrophy, obesity, and loss of sympathetic innervation to the liver are believed to contribute to risks of these abnor
Externí odkaz:
https://doaj.org/article/994cd3d0413242809a7a25ee08c61800
Autor:
Xin-Hua Liu, Zachary A. Graham, Lauren Harlow, Jiangping Pan, Daniella Azulai, William A. Bauman, Joshua Yarrow, Christopher P. Cardozo
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Spinal cord injury (SCI) results in dysregulation of carbohydrate and lipid metabolism; the underlying cellular and physiological mechanisms remain unclear. Fibroblast growth factor 21 (FGF21) is a circulating protein primarily secreted by the liver
Externí odkaz:
https://doaj.org/article/8801932ce00d4b0abb6cbad015707bb6
Autor:
Abdurrahman Aslan, Lauren Harlow, Xin-Hua Liu, Rita De Gasperi, William A. Bauman, Marco Brotto, Christopher P Cardozo
Publikováno v:
International Journal of Medical Sciences. 20:376-384
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6c4dde70edc24fdde348e9ae98872f9
https://doi.org/10.7150/ijms.77603
https://doi.org/10.7150/ijms.77603
Autor:
Luke A. Potter, Carlos A. Toro, Lauren Harlow, Kaleen M. Lavin, Christopher P. Cardozo, Adam R. Wende, Zachary A. Graham
Publikováno v:
Physiological Genomics.
Spinal cord injury (SCI) results in rapid muscle loss. The mechanisms of muscle atrophy have been well-described but there is limited information specific to SCI. Exogenous molecular interventions to slow muscle atrophy in severe-to-complete SCI have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c84d2fda884aac3485d69cf7917d2a
https://doi.org/10.1152/physiolgenomics.00129.2022
https://doi.org/10.1152/physiolgenomics.00129.2022
Autor:
Rita De Gasperi, Jiangping Pan, Christopher Cardozo, Christopher N Goulbourne, Chenglin Mo, Daniella Azulai, William A. Bauman, Fred C. Ko, Bin Zhang, Lei Guo, Ashleigh M. Raczkowski, Xin-Hua Liu, Marco Brotto, Wei Zhao, Yating Du, Zachary A. Graham, Zhiying Wang, Lauren Harlow
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 454-466 (2022)
BackgroundThe role of Numb, a protein that is important for cell fate and development was investigated in adult skeletal muscle in mice using a conditional, inducible knockout (cKO) model.MethodsNumb expression was evaluated by Western blot. Numb loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5678ea7c97a0f5dd82a99c4ac72a41a6
https://doaj.org/article/e3de719d0af0427d8b54e419b4474d11
https://doaj.org/article/e3de719d0af0427d8b54e419b4474d11
Autor:
Xin-Hua Liu, Christopher Cardozo, Alex J Mattingly, Daniella Azulai, Joshua F. Yarrow, Jiangping Pan, Russell D Wnek, Hesham M. Tawfeek, William A. Bauman, Zachary A. Graham, Lauren Harlow
Publikováno v:
Neurotrauma Reports
Spinal cord injury (SCI) is associated with obesity and is a risk factor for type 2 diabetes mellitus (T2DM). Immobilization, muscle atrophy, obesity, and loss of sympathetic innervation to the liver are believed to contribute to risks of these abnor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9269ac2f727713777e6717a904f38f
https://doi.org/10.1089/neur.2020.0014
https://doi.org/10.1089/neur.2020.0014
Autor:
Samantha L Asche-Godin, Adina Israel, Fred C. Ko, Christopher Cardozo, Lauren Harlow, Zachary A. Graham, Marco Brotto, Zhiying Wang, Weihua Huang, Charles V. Mobbs
Publikováno v:
J Gerontol A Biol Sci Med Sci
This study aimed to characterize the effects of laparotomy on post-operative physical function and skeletal muscle gene expression in C57BL/6N mice at 3, 20 and 24 months of age to investigate late-life vulnerability and resiliency to acute surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8728f34ddfc0d61d7cbb3fb6d0ac99
https://europepmc.org/articles/PMC9536457/
https://europepmc.org/articles/PMC9536457/
