Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lauren Hanson"'
Fibre jamming is a relatively new and understudied soft robotic mechanism that has previously found success when used in stiffness-tuneable arms and fingers. However, to date researchers have not fully taken advantage of the freedom offered by contem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1df8add4a25ed1b0f4297491cb3f6c6
http://arxiv.org/abs/2109.04681
http://arxiv.org/abs/2109.04681
Autor:
Nicolas Hudson, Fletcher Talbot, Mark Cox, Jason Williams, Thomas Hines, Alex Pitt, Brett Wood, Dennis Frousheger, Katrina Lo Surdo, Thomas Molnar, Ryan Steindl, Matt Wildie, Inkyu Sa, Navinda Kottege, Kazys Stepanas, Emili Hernandez, Gavin Catt, William Docherty, Brendan Tidd, Benjamin Tam, Simon Murrell, Mitchell Bessell, Lauren Hanson, Lachlan Tychsen-Smith, Hajime Suzuki, Leslie Overs, Farid Kendoul, Glenn Wagner, Duncan Palmer, Peter Milani, Matthew O’Brien, Shu Jiang, Shengkang Chen, Ronald Arkin
Heterogeneous teams of robots, leveraging a balance between autonomy and human interaction, bring powerful capabilities to the problem of exploring dangerous, unstructured subterranean environments. Here we describe the solution developed by Team CSI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843d8167c881cdc45bfc4a8aa23a805f
http://arxiv.org/abs/2104.09053
http://arxiv.org/abs/2104.09053
Autor:
Jay B, Fell, John P, Fischer, Brian R, Baer, James F, Blake, Karyn, Bouhana, David M, Briere, Karin D, Brown, Laurence E, Burgess, Aaron C, Burns, Michael R, Burkard, Harrah, Chiang, Mark J, Chicarelli, Adam W, Cook, John J, Gaudino, Jill, Hallin, Lauren, Hanson, Dylan P, Hartley, Erik J, Hicken, Gary P, Hingorani, Ronald J, Hinklin, Macedonio J, Mejia, Peter, Olson, Jennifer N, Otten, Susan P, Rhodes, Martha E, Rodriguez, Pavel, Savechenkov, Darin J, Smith, Niranjan, Sudhakar, Francis X, Sullivan, Tony P, Tang, Guy P, Vigers, Lance, Wollenberg, James G, Christensen, Matthew A, Marx
Publikováno v:
Journal of medicinal chemistry. 63(13)
Capping off an era marred by drug development failures and punctuated by waning interest and presumed intractability toward direct targeting of KRAS, new technologies and strategies are aiding in the target's resurgence. As previously reported, the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc99717000ce420f505732f20b4224e4
https://pubmed.ncbi.nlm.nih.gov/32250617
https://pubmed.ncbi.nlm.nih.gov/32250617
Autor:
Joshua Ballard, Harrah Chiang, James G. Christensen, Kenneth Hee, Tony Pisal Tang, Brian R. Baer, Peter Olson, Henry J. Zecca, David Briere, Mark Joseph Chicarelli, Laurence E. Burgess, Karyn Bouhana, Jill Hallin, Matthew A. Marx, Lauren Hanson, Barbara J. Brandhuber, Michael Burkard, Fell Jay Bradford, Pavel Savechenkov, James F. Blake, John P. Fischer, Guy Vigers, Hicken Erik James, Niranjan Sudhakar, Kevin Davidson, Ronald Jay Hinklin, Macedonio J. Mejia, John Gaudino
Publikováno v:
ACS Medicinal Chemistry Letters. 9:1230-1234
[Image: see text] KRAS is the most frequently mutated driver oncogene in human cancer, and KRAS mutations are commonly associated with poor prognosis and resistance to standard treatment. The ability to effectively target and block the function of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a511b6ef25dc7584d5aa3f9ed4d78a97
https://doi.org/10.1021/acsmedchemlett.8b00382
https://doi.org/10.1021/acsmedchemlett.8b00382
Autor:
Takashi Kohno, Steve Smith, Shingo Matsumoto, Barbara J. Brandhuber, Edward Y. Zhu, Michael Burkard, Kevin Ronald Condroski, Lauren Hanson, LouAnn Cable, Kevin Ebata, Lori J. Wirth, Hibiki Udagawa, Brian B. Tuch, S. Michael Rothenberg, Steve Andrews, Koichi Goto, Michele Nguyen, Genichiro Ishii, James F. Blake
Publikováno v:
JCO Precision Oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e467ac4bfe837d19e6f3abbbd7030917
http://europepmc.org/articles/PMC7446343
http://europepmc.org/articles/PMC7446343
Autor:
Francis J. Sullivan, Jessica Gaffney, Kevin Ebata, Shannon L. Winski, Michael Burkard, S. Michael Rothenberg, Lance Williams, Jennifer A. Low, Guy Vigers, Ross D. Wallace, Brian B. Tuch, Nisha Nanda, James F. Blake, Lauren Hanson, Tony Morales, Karyn Bouhana, Andrews Steven W, Barbara J. Brandhuber, Julia Haas, Jiang Yutong
Publikováno v:
Molecular Cancer Therapeutics. 14:B192-B192
Background: Activating mutations and oncogenic fusions of the RET receptor tyrosine kinase have been identified in multiple tumor types, including thyroid, lung, breast and colon carcinoma. Furthermore, tyrosine kinase inhibitors (TKIs) with anti-RET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::998422c9657400ea130920c1ebf76809
https://doi.org/10.1158/1535-7163.targ-15-b192
https://doi.org/10.1158/1535-7163.targ-15-b192