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Publikováno v:
Seminars in Immunopathology. 44:625-648
Ischemic stroke generates an immune response that contributes to neuronal loss as well as tissue repair. This is a complex process involving a range of cell types and effector molecules and impacts tissues outside of the CNS. Recent reviews address s
Autor:
Jonathan Howard DeLong, Sofia Evelyn Velazquez, Leonardo Shiuchi Sun, Margaret J Landreneau, Lauren Hachmann Sansing
Publikováno v:
The Journal of Immunology. 208:111.23-111.23
Introduction Monocyte-derived macrophages contribute to neurotoxic inflammation during hemorrhagic stroke. Cholesterol is an immunosuppressive molecule present at high levels in the brain, primarily as a component of myelin. Uptake of myelin and acti