Výsledky vyhledávání - "Lauren H. Kim"

Akademický článek

IFNγ-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

Abstract Obesity is a major cause of metabolic dysfunction-associated steatohepatitis (MASH) and is characterized by inflammation and insulin resistance. Interferon-γ (IFNγ) is a pro-inflammatory cytokine elevated in obesity and modulating macropha

Externí odkaz: https://doaj.org/article/8e5cb5e93c2e43288feb95e635cd27f8

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270-OR: Loss of Myeloid IFNgamma Signaling Prevents Hepatic Inflammation and NASH in Obesity

Autor: RANDALL H. FRIEDLINE, MAHAA ALBUSHARIF, HYE LIM NOH, ALLISON M. KIM, LAUREN H. KIM, DORIS X.T. ZHENG, GLENNA SWINAND, ANNIKA BEAVERSON, XIAODI HU, LAUREN A. TAUER, WERNER MULLER, JASON K. KIM

Publikováno v: Diabetes. 71

Nonalcoholic steatohepatitis (NASH) is a major complication of obesity, and interferon-γ (IFNγ) is a key regulator of innate and adaptive immunity by priming macrophages and inducing an inflammatory response. We have recently generated mice with co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6629d290dfddeccef169683dd3a87fb1
https://doi.org/10.2337/db22-270-or

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1726-P: Male Mice Lacking Estrogen Receptor Beta Develop Obesity but Are Protected from Diet-Induced Insulin Resistance in Skeletal Muscle

Autor: Randall H. Friedline, Xiaodi Hu, Duy A. Tran, Lauren H. Kim, Amy L. Roberts, Karen A. Dunphy, Jason K. Kim, Ceren Goral, D. Joseph Jerry, Sujin Suk, Allison M. Kim, Hye Lim Noh, Lauren A. Tauer

Publikováno v: Diabetes. 69

Estrogen has an important role in regulating female metabolism. Whereas the role of estrogen receptor (ER) α on female reproductive system is well defined, the role of ERβ (encoded by Esr2) remains unclear. Here we examined the metabolic effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e97284fac72dd50d6b561140aec2ec36
https://doi.org/10.2337/db20-1726-p

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1727-P: Mice Deficient in Myeloid Cell-Derived Interleukin-1a Are Protected from Diet-Induced Obesity and Insulin Resistance

Autor: Hye Lim Noh, Randall H. Friedline, Jason K. Kim, Duy A. Tran, Lauren A. Tauer, Lauren H. Kim, Xiaodi Hu, Sujin Suk, Allison M. Kim

Publikováno v: Diabetes. 69

Interleukin (IL)-1α is a major mediator of inflammation, and functional polymorphism of IL-1α is associated with human obesity. We have recently generated mice with genetic ablation of IL-1α selectively in myeloid cells. On chow diet, Lyz-IL-1α K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::efe4c1588a474172969ad115cbd80514
https://doi.org/10.2337/db20-1727-p

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Rehabilitation Practitioners' Prioritized Care Processes in Hip Fracture Post-Acute Care

Autor: Lauren H Kim, Natalie E. Leland

Occupational and physical therapy in post-acute care (PAC) has reached the point where quality indicators for hip fracture are needed. This study characterizes the practitioners' prioritized hip fracture rehabilitation practices, which can guide futu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c30a8577a5ed0657d86e7c44da8140
https://europepmc.org/articles/PMC5628754/

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