Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lauren H McCarl"'
Autor:
Alexandra Foster, Shubhanchi Nigam, David S Tatum, Itay Raphael, Jide Xu, Rajeev Kumar, Elizabeth Plakseychuk, Joseph D Latoche, Sarah Vincze, Bo Li, Rajan Giri, Lauren H McCarl, Robert Edinger, Murat Ak, Vishal Peddagangireddy, Lesley M Foley, T Kevin Hitchens, Rivka R Colen, Ian F Pollack, Ashok Panigrahy, Darren Magda, Carolyn J Anderson, W Barry Edwards, Gary Kohanbash
Publikováno v:
EBioMedicine, Vol 71, Iss , Pp 103571- (2021)
Background: Malignant gliomas are deadly tumours with few therapeutic options. Although immunotherapy may be a promising therapeutic strategy for treating gliomas, a significant barrier is the CD11b+ tumour-associated myeloid cells (TAMCs), a heterog
Externí odkaz:
https://doaj.org/article/262ba25f595340aea3143132472fdff3
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102049- (2023)
Summary: Understanding the glioblastoma (GBM) immune microenvironment and development of clinical treatment drugs rely on suitable preclinical GBM models. Here, we present a protocol to establish syngeneic orthotopic glioma mouse models. We also desc
Externí odkaz:
https://doaj.org/article/3c206ee7b98a469e817eea6b1b057479
Autor:
Brian J. Golbourn, Matthew E. Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah, Nisha Kabir, Ann-Catherine J. Stanton, Abigail L. Locke, Stephanie M. Casillo, Yanhua Zhao, Lauren M. Sanders, Allison Cheney, Steven J. Mullett, Apeng Chen, Michelle Wassell, Anthony Andren, Jennifer Perez, Esther P. Jane, Daniel R. David Premkumar, Robert F. Koncar, Shideh Mirhadi, Lauren H. McCarl, Yue-Fang Chang, Yijen L. Wu, Taylor A. Gatesman, Andrea F. Cruz, Michal Zapotocky, Baoli Hu, Gary Kohanbash, Xiuxing Wang, Alenoush Vartanian, Michael F. Moran, Frank Lieberman, Nduka M. Amankulor, Stacy G. Wendell, Olena M. Vaske, Ashok Panigrahy, James Felker, Kelsey C. Bertrand, Claudia L. Kleinman, Jeremy N. Rich, Robert M. Friedlander, Alberto Broniscer, Costas Lyssiotis, Nada Jabado, Ian F. Pollack, Stephen C. Mack, Sameer Agnihotri
Publikováno v:
Nature Cancer. 3:899-899
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2b46c5405522ed2558365adcae3a22
https://doi.org/10.1038/s43018-022-00407-9
https://doi.org/10.1038/s43018-022-00407-9
Autor:
Itay Raphael, Rajeev Kumar, Lauren H. McCarl, Karsen Shoger, Lin Wang, Poorva Sandlesh, Chaim T. Sneiderman, Jordan Allen, Shuyan Zhai, Marissa Lynn Campagna, Alexandra Foster, Tullia C. Bruno, Sameer Agnihotri, Baoli Hu, Brandyn A. Castro, Frank S. Lieberman, Alberto Broniscer, Aaron A. Diaz, Nduka M. Amankulor, Dhivyaa Rajasundaram, Ian F. Pollack, Gary Kohanbash
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
Glioblastoma (GBM) remains an aggressive brain tumor with a high rate of mortality. Immune checkpoint (IC) molecules are expressed on tumor infiltrating lymphocytes (TILs) and promote T cell exhaustion upon binding to IC ligands expressed by the tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d13aa01e9b6dfd7fb67dafb3a56f3b
https://www.frontiersin.org/articles/10.3389/fimmu.2021.637146/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.637146/full
Autor:
Brian J. Golbourn, Matthew E. Halbert, Katharine Halligan, Srinidhi Varadharajan, Brian Krug, Nneka E. Mbah, Nisha Kabir, Ann-Catherine J. Stanton, Abigail L. Locke, Stephanie M. Casillo, Yanhua Zhao, Lauren M. Sanders, Allison Cheney, Steven J. Mullett, Apeng Chen, Michelle Wassell, Anthony Andren, Jennifer Perez, Esther P. Jane, Daniel R. David Premkumar, Robert F. Koncar, Shideh Mirhadi, Lauren H. McCarl, Yue-Fang Chang, Yijen L. Wu, Taylor A. Gatesman, Andrea F. Cruz, Michal Zapotocky, Baoli Hu, Gary Kohanbash, Xiuxing Wang, Alenoush Vartanian, Michael F. Moran, Frank Lieberman, Nduka M. Amankulor, Stacy G. Wendell, Olena M. Vaske, Ashok Panigrahy, James Felker, Kelsey C. Bertrand, Claudia L. Kleinman, Jeremy N. Rich, Robert M. Friedlander, Alberto Broniscer, Costas Lyssiotis, Nada Jabado, Ian F. Pollack, Stephen C. Mack, Sameer Agnihotri
Publikováno v:
Nat Cancer
Diffuse midline gliomas (DMGs) bearing driver mutations of histone 3 lysine 27 (H3K27M) are incurable brain tumors with unique epigenomes. Here, we generated a syngeneic H3K27M mouse model to study the amino acid metabolic dependencies of these tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece83b9114ea9bb4dec9365652e59e17
https://pubmed.ncbi.nlm.nih.gov/35739422
https://pubmed.ncbi.nlm.nih.gov/35739422