Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lauren Farr"'
Autor:
Devra Olson, Yen Lin Chia, Enaharo Iboi, Lauren Farr, Maddy Burcher, Anthony Lee, Kelly Hensley, Sean Allred, Abbie Wong, Masashi Shimazaki, Masamichi Mori, Sharsti Sandall, Christopher Carosino
Publikováno v:
Cancer Research. 83:LB246-LB246
Enfortumab vedotin (EV) is a monomethyl auristatin E (MMAE)-containing antibody-drug conjugate directed to Nectin-4, which is highly expressed in bladder cancers. Preclinically, EV has demonstrated tumor cell killing by direct cytotoxicity and bystan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecbc389645028849f7d4c6fea700789
https://doi.org/10.1158/1538-7445.am2023-lb246
https://doi.org/10.1158/1538-7445.am2023-lb246
Autor:
Esther S. Trueblood, Steven Jin, Uland Y. Lau, Francisco Zapata, Lauren Bou, Lauren Farr, David Ortiz, Jessica K. Simmons, Kim K. Emmerton, Ryan Lyski, Julia H. Cochran, Scott C. Jeffrey, Maureen Ryan, Margo Zaval, Nicole M. Okeley, Peter D. Senter, Katie Snead, David W. Meyer
Publikováno v:
Molecular Cancer Therapeutics. 20:329-339
We have developed a highly active and well-tolerated camptothecin (CPT) drug-linker designed for antibody-mediated drug delivery in which the lead molecule consists of a 7-aminomethyl-10,11-methylenedioxy CPT (CPT1) derivative payload attached to a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b216df9ed51afa64da2a7b5ad17ed50
https://doi.org/10.1158/1535-7163.mct-20-0526
https://doi.org/10.1158/1535-7163.mct-20-0526
Autor:
Timothy S. Lewis, Devra Olson, Margo Zaval, Robert Thurman, Shawna Hengel, Scott Peterson, Lauren Farr, Anita Kulukian, Janelle Taylor
Publikováno v:
Cancer Research. 80:P1-18
Background: Tucatinib is an orally administered, reversible HER2-targeted small molecule tyrosine kinase inhibitor that potently and selectively inhibits HER2 relative to the closely related kinase EGFR. In a phase Ib clinical trial in HER2+ metastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb02ebb0b67b9300e1a1b51d403ad518
https://doi.org/10.1158/1538-7445.sabcs19-p1-18-09
https://doi.org/10.1158/1538-7445.sabcs19-p1-18-09
Autor:
Christopher Carosino, Devra Olson, Katie Snead, Anthony Lee, Lauren Farr, Amit Garg, Christine O'Day, Esther Trueblood, Jennifer Wright, Mark Bieda, Charles Caldwell, Kelly Hensley, Sean Allred, Bernard Liu, Masashi Shimazaki, Sharsti Sandall
Publikováno v:
Cancer Research. 82:1140-1140
Enfortumab vedotin (EV) is a monomethyl auristatin E (MMAE) containing antibody-drug conjugate directed to Nectin-4, which is highly expressed in bladder cancers. Preclinically, EV has demonstrated tumor cell-killing by direct cytotoxicity, bystander
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e0c6bc1ec8b3a440f18b9a038adefc
https://doi.org/10.1158/1538-7445.am2022-1140
https://doi.org/10.1158/1538-7445.am2022-1140
Autor:
Scott C. Jeffrey, Peter D. Senter, Nicole M. Okeley, Shawna Hengel, Julia H. Cochran, Lauren Farr, Ryan Lyski
Publikováno v:
Cancer Research. 80:2895-2895
Camptothecins (CPT) are an important class of molecules that have been employed in cancer therapy for the past 20 years. These molecules interact with the DNA-topoisomerase I complex leading to double-strand breaks and cell death. While these molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6acf45894b659c13e5d4829a5091f52
https://doi.org/10.1158/1538-7445.am2020-2895
https://doi.org/10.1158/1538-7445.am2020-2895
Publikováno v:
Epidemics, Vol 44, Iss , Pp 100693- (2023)
The current global outbreaks of mpox is a unique infectious disease in the way it seems to be transmitting: it has been observed to be highly concentrated in communities of men who have sex with men (MSM) through pair formation, and also provides lon
Externí odkaz:
https://doaj.org/article/2f97fc0053354759961455dd958acb69
Publikováno v:
Journal of Medical Radiation Sciences, Vol 69, Iss 2, Pp 182-190 (2022)
Abstract Introduction While studies have investigated influences on graduate practice locations of other health professionals, especially medicine, none have investigated practice locations of medical radiation science (MRS) graduates. This study aim
Externí odkaz:
https://doaj.org/article/bb76de2a187243bb930d0f77fd402f23
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Interactions between bacteria and the viruses that infect them (i.e., phages) have profound effects on biological processes, but despite their importance, little is known on the general structure of infection and resistance between most phages and ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e084c65e7b140aad267a03269deab979
http://hdl.handle.net/10261/43503
http://hdl.handle.net/10261/43503
