Výsledky vyhledávání - "Lauren F. Borkowski"

Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats

Autor: Corey Smith, Thomas E. Dick, David Litvin, Lauren F. Borkowski, Frank J. Jacono, Scott J. Denstaedt, Nicole L. Nichols

Publikováno v: Brain Behav Immun

The pathways for peripheral-to-central immune communication (P → C I-comm) following sterile lung injury (SLI) are unknown. SLI evokes systemic and central inflammation, which alters central respiratory control and viscerosensory transmission in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7883cbb9b5218453a1fa221ebcab0789
https://doi.org/10.1016/j.bbi.2020.02.006

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Divergent receptor utilization is necessary for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections

Autor: Lauren F. Borkowski, Nicole L. Nichols, Amy N Keilholz, Catherine L Smith

Publikováno v: J Neurophysiol

Intrapleural injection of cholera toxin B conjugated to saporin (CTB-SAP) mimics respiratory motor neuron death and respiratory deficits observed in rat models of neuromuscular diseases. Seven-day CTB-SAP rats elicit enhanced phrenic long-term facili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9e43c79a4f5ce317b86a464b24367c
https://pubmed.ncbi.nlm.nih.gov/34288779

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Differential mechanisms are required for phrenic long-term facilitation over the course of motor neuron loss following CTB-SAP intrapleural injections

Autor: Lauren F. Borkowski, Nicole L. Nichols

Publikováno v: Experimental neurology. 334

Selective elimination of respiratory motor neurons using intrapleural injections of cholera toxin B fragment conjugated to saporin (CTB-SAP) mimics motor neuron death and respiratory deficits observed in rat models of neuromuscular diseases. This CTB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f680f6422d19bc60fecd9b2a293735fd
https://pubmed.ncbi.nlm.nih.gov/32916172

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Nonsteroidal anti-inflammatory drug (ketoprofen) delivery differentially impacts phrenic long-term facilitation in rats with motor neuron death induced by intrapleural CTB-SAP injections

Autor: Nicole L. Nichols, Kaylie A. Canda, Catherine L Smith, Lauren F. Borkowski, Amy N Keilholz

Publikováno v: Experimental Neurology. 347:113892

Intrapleural injections of cholera toxin B conjugated to saporin (CTB-SAP) selectively eliminates respiratory (e.g., phrenic) motor neurons, and mimics motor neuron death and respiratory deficits observed in rat models of neuromuscular diseases. Addi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bb5a24b44558b01d67593e1a7266a6
https://doi.org/10.1016/j.expneurol.2021.113892

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5-HT2A/B receptor expression in the phrenic motor nucleus in a rat model of ALS (SOD1

Autor: Lauren F, Borkowski, Taylor A, Craig, Olivia E, Stricklin, Katherine A, Johnson, Nicole L, Nichols

Publikováno v: Respir Physiol Neurobiol

Despite respiratory motor neuron death, ventilation is preserved in SOD1(G93A) rats. Compensatory respiratory plasticity may counterbalance the loss of these neurons. Phrenic long-term facilitation (pLTF; a form of respiratory plasticity) in naïve r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9283ef157231c080f7036a424c8a25e
https://pubmed.ncbi.nlm.nih.gov/32504811

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5-HT2A/B receptor expression in the phrenic motor nucleus in a rat model of ALS (SOD1G93A)

Autor: Nicole L. Nichols, Lauren F. Borkowski, Taylor A. Craig, Katherine A. Johnson, Olivia E. Stricklin

Publikováno v: Respiratory Physiology & Neurobiology. 279:103471

Despite respiratory motor neuron death, ventilation is preserved in SOD1G93A rats. Compensatory respiratory plasticity may counterbalance the loss of these neurons. Phrenic long-term facilitation (pLTF; a form of respiratory plasticity) in naive rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0dc8e1ead7008aeb0040726cb94f701d
https://doi.org/10.1016/j.resp.2020.103471

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