Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lauren Endres"'
Autor:
Andrea Leonardi, Nataliia Kovalchuk, Lei Yin, Lauren Endres, Sara Evke, Steven Nevins, Samuel Martin, Peter C. Dedon, J. Andres Melendez, Laura Van Winkle, Qing-Yu Zhang, Xinxin Ding, Thomas J. Begley
Publikováno v:
Epigenetics, Vol 15, Iss 10, Pp 1121-1138 (2020)
The epitranscriptomic writer Alkylation Repair Homolog 8 (ALKBH8) is a transfer RNA (tRNA) methyltransferase that modifies the wobble uridine of selenocysteine tRNA to promote the specialized translation of selenoproteins. Using Alkbh8 deficient (Alk
Externí odkaz:
https://doaj.org/article/d464ab1c8bef4c1bb173527d6328c626
Autor:
Lauren Endres, Rebecca E Rose, Frank Doyle, Taylor Rahn, Bethany Lee, Jessica Seaman, William D McIntyre, Daniele Fabris
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0229103 (2020)
Chemical modifications that regulate protein expression at the translational level are emerging as vital components of the cellular stress response. Transfer RNAs (tRNAs) are significant targets for methyl-based modifications, which are catalyzed by
Externí odkaz:
https://doaj.org/article/6f904a636b0a436cb1750c7abcb6490e
Autor:
Beth L. Worley, Yeon Soo Kim, Jennifer Mardini, Rameez Zaman, Kelly E. Leon, Piyushi Gupta Vallur, Asvelt Nduwumwami, Joshua I. Warrick, Patrick F. Timmins, Joshua P. Kesterson, Rébécca Phaëton, Nam Y. Lee, Vonn Walter, Lauren Endres, Karthikeyan Mythreye, Katherine M. Aird, Nadine Hempel
Publikováno v:
Redox Biology, Vol 25, Iss , Pp - (2019)
Ovarian cancer remains the most lethal gynecologic malignancy, and is primarily diagnosed at late stage when considerable metastasis has occurred in the peritoneal cavity. At late stage abdominal cavity ascites accumulation provides a tumor-supportin
Externí odkaz:
https://doaj.org/article/0ee39ed6b42940489efa251bb7ae9eb6
Autor:
Michael Fasullo, Lauren Endres
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 9431-9449 (2015)
Nucleotide balance is critically important not only in replicating cells but also in quiescent cells. This is especially true in the nervous system, where there is a high demand for adenosine triphosphate (ATP) produced from mitochondria. Mitochondri
Externí odkaz:
https://doaj.org/article/d319741ac3484668a7fa666fba737882
Autor:
Lauren Endres, Ulrike Begley, Ryan Clark, Chen Gu, Agnieszka Dziergowska, Andrzej Małkiewicz, J Andres Melendez, Peter C Dedon, Thomas J Begley
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131335 (2015)
Environmental and metabolic sources of reactive oxygen species (ROS) can damage DNA, proteins and lipids to promote disease. Regulation of gene expression can prevent this damage and can include increased transcription, translation and post translati
Externí odkaz:
https://doaj.org/article/927994c38bea431094899665c4138eaa
Autor:
Lauren Endres, Mackenzie Bishop, Carol R. Scheerer, Kristen Brokamp, Lauryn Stauble, Breanna P. Lynch, Becky Hagedorn
Publikováno v:
Journal of Occupational Therapy, Schools, & Early Intervention. 15:357-373
Publikováno v:
Future Med Chem
Transfer RNAs (tRNAs) undergo extensive chemical modification within cells through the activity of tRNA methyltransferase enzymes (TRMs). Although tRNA modifications are dynamic, how they impact cell behavior after stress and during tumorigenesis is
Autor:
Antonietta F. Hansen, James H. Keith, Lauren Endres, Brian McCandless, Thomas J. Begley, Yiching Hseih, Ulrike Begley, Laurence Kaminsky
Publikováno v:
Advances in Bioscience and Biotechnology. :228-247
Technologies that measure activation of components of the DNA damage response (DDR) have applications in exposure assessment and personalized medicine. The DDR and associated DNA repair pathways encompass hundreds of proteins, making detailed measure
Autor:
Scott A. Tenenbaum, Francis Doyle, Peter C. Dedon, Andrea Leonardi, Lauren Endres, Thomas J. Begley
Publikováno v:
PMC
The translation of mRNA in all forms of life uses a three-nucleotide codon and aminoacyl-tRNAs to synthesize a protein. There are 64 possible codons in the genetic code, with codons for the ∼20 amino acids and 3 stop codons having 1- to 6-fold dege
Autor:
Xinxin Ding, Nataliia Kovalchuk, Steven Nevins, Qing Yu Zhang, Lauren Endres, Andrea Leonardi, J. Andres Melendez, Lei Yin, Sara Evke, Laura S. Van Winkle, Thomas J. Begley, Samuel Martin, Peter C. Dedon
BackgroundThe epitranscriptomic writer Alkylation Repair Homolog 8 (ALKBH8) is a tRNA methyltransferase that modifies the wobble uridine of selenocysteine tRNA to promote the specialized translation, via stop codon recoding, of proteins that contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebb76c493548bf9e14f5ea4d9043ca6