Výsledky vyhledávání - "Lauren E. Pope"

Akademický článek

Quaternary Structure, Salt Sensitivity, and Allosteric Regulation of β-AMYLASE2 From Arabidopsis thaliana

Autor: Jonathan D. Monroe, Lauren E. Pope, Jillian S. Breault, Christopher E. Berndsen, Amanda R. Storm

Publikováno v: Frontiers in Plant Science, Vol 9 (2018)

The β-amylase family in Arabidopsis thaliana has nine members, four of which are both plastid-localized and, based on active-site sequence conservation, potentially capable of hydrolyzing starch to maltose. We recently reported that one of these enz

Externí odkaz: https://doaj.org/article/f2fd0472d5c24effa786eaedf9b26e9d

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The Role of Monounsaturated Fatty Acids in Ferroptosis

Autor: Lauren E. Pope, Scott Dixon

Publikováno v: The FASEB Journal. 36

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::320c08d514a564a726cbc27132b119fa
https://doi.org/10.1096/fasebj.2022.36.s1.0r871

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Reactivity-Based Probe of the Iron(II)-Dependent Interactome Identifies New Cellular Modulators of Ferroptosis

Autor: Ying-Chu Chen, Scott J. Dixon, Juan A. Oses-Prieto, Lauren E Pope, Alma L. Burlingame, Adam R. Renslo

Publikováno v: J Am Chem Soc

Ferroptosis is an iron-dependent form of cell death resulting from loss or inhibition of cellular machinery that protects from the accumulation of lipid hydroperoxides. Ferroptosis likely serves a tumor suppressing function in normal cellular homeost

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c878caea1399ea4b024323ab558fb95f
https://doi.org/10.1021/jacs.0c06709

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Ferroptosis Regulation by the NGLY1/NFE2L1 Pathway

Autor: Giovanni C. Forcina, Magdalena Murray, Carolyn R. Bertozzi, Monther Abu-Remaileh, Lauren E Pope, Wentao Dong, Scott J. Dixon

Ferroptosis is an oxidative form of non-apoptotic cell death whose transcriptional regulation is poorly understood. Cap’n’collar (CNC) transcription factors including Nuclear Factor Erythroid-2 Related Factor 1 (NFE2L1/NRF1) and NFE2L2 (NRF2) are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfaa211abe626f3c09015db071c3bd6e
https://doi.org/10.1101/2021.10.12.463965

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Context-dependent regulation of ferroptosis sensitivity

Autor: Leslie Magtanong, Grace D. Mueller, Kevin J. Williams, Maximilian Billmann, Katherine Chan, David A. Armenta, Lauren E. Pope, Jason Moffat, Charles Boone, Chad L. Myers, James A. Olzmann, Steven J. Bensinger, Scott J. Dixon

Publikováno v: Cell chemical biology. 29(9)

Ferroptosis is an important mediator of pathophysiological cell death and an emerging target for cancer therapy. Whether ferroptosis sensitivity is governed by a single regulatory mechanism is unclear. Here, based on the integration of 24 published c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba942fc9ce7a0a6c70c628fef4802afa
https://pubmed.ncbi.nlm.nih.gov/36270234

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Arabidopsis β-Amylase2 Is a K+-Requiring, Catalytic Tetramer with Sigmoidal Kinetics

Autor: Tewaldemedhine B. Gebrejesus, Catherine E. Torres, Jonathan D. Monroe, Amanda R. Storm, Christopher E. Berndsen, Jillian S. Breault, Lauren E. Pope

Publikováno v: Plant Physiology. 175:1525-1535

The Arabidopsis (Arabidopsis thaliana) genome contains nine β-amylase (BAM) genes, some of which play important roles in starch hydrolysis. However, little is known about BAM2, a plastid-localized enzyme reported to have extremely low catalytic acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6be823efeb023c9b7669a2dcac7877e0
https://doi.org/10.1104/pp.17.01506

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