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pro vyhledávání: '"Lauren E. Nickolay"'
Autor:
James L. Riley, Megan Estorninho, Lauren E. Nickolay, Timothy Tree, Caroline M. Hull, Max W. Richardson, John Maher, Mark Peakman
Publikováno v:
Hull, C M, Nickolay, L E, Estorninho, M, Richardson, M W, Riley, J L, Peakman, M, Maher, J & Tree, T I M 2017, ' Generation of human islet-specific regulatory T cells by TCR gene transfer ', Journal of Autoimmunity, vol. 79, pp. 63-73 . https://doi.org/10.1016/j.jaut.2017.01.001
Based on the success in animal models of type 1 diabetes (T1D), clinical trials of adoptive regulatory T cell (Treg) therapy are underway using ex vivo expanded polyclonal Tregs. However, pre-clinical data also demonstrate that islet-specific Tregs a
Autor:
Angie Rupp, Lauren E. Nickolay, Kathryn Carrick, John D. Pediani, Hugh J. Willison, Kay N. Greenshields, Jaap J. Plomp, Simon N. Fewou
Publikováno v:
Journal of Clinical Investigation, 122(3), 1037-1051
In the Guillain-Barre syndrome subform acute motor axonal neuropathy (AMAN), Campylobacter jejuni enteritis triggers the production of anti-ganglioside Abs (AGAbs), leading to immune-mediated injury of distal motor nerves. An important question has b