Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lauren E. Bollinger"'
Autor:
Mingxing Wang, Bo Wu, Jason D. Tucker, Sapana N. Shah, Peijuan Lu, Lauren E. Bollinger, Qilong Lu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 120-131 (2017)
We investigated a series of Tween 85 modified low molecular weight polyethylenimine (LPEI, 0.8k/1.2k/2.0k)-copolymers (Zs) through simple formulation and covalent conjugation with phosphorodiamidate morpholino oligomer (PMO) for their potential to en
Externí odkaz:
https://doaj.org/article/985ebf81ea7a41488b40a0647c02a400
Publikováno v:
Journal of materials chemistry. B. 3(26)
A series of cationic amphiphlic copolymers (Z series) constructed from Tween 85 and low molecular weight (Mw) polyethyleneimine (LPEI) have been evaluated for the delivery of antisense 2′-O-methyl phosphorothioate RNA (2′-OMePS) in both cell cult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94081ffb33c4a8572fadaf3384deeea2
https://pubmed.ncbi.nlm.nih.gov/32262609
https://pubmed.ncbi.nlm.nih.gov/32262609
Autor:
Lauren E. Bollinger, Qilong Lu, Mingxing Wang, Bo Wu, Jason D. Tucker, Sapana N. Shah, Peijuan Lu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 9, Iss C, Pp 120-131 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
We investigated a series of Tween 85 modified low molecular weight polyethylenimine (LPEI, 0.8k/1.2k/2.0k)-copolymers (Zs) through simple formulation and covalent conjugation with phosphorodiamidate morpholino oligomer (PMO) for their potential to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff645d8bfd495553bfa054f092cef6f
http://www.sciencedirect.com/science/article/pii/S2162253117302561
http://www.sciencedirect.com/science/article/pii/S2162253117302561
Autor:
Amy Harper, Sapana N. Shah, Peijuan Lu, Qi L. Lu, Lauren E. Bollinger, Bo Wu, Susan Sparks, Anthony Blaeser
Publikováno v:
The American journal of pathology. 188(4)
The third most common form of limb-girdle muscular dystrophies is caused by mutations of the Fukutin-related protein ( FKRP ) gene, with no effective therapy available. Selective estrogen receptor modulators, tamoxifen and raloxifene, have been widel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd3bc1bd33e551bdca67dda7ae34952
https://pubmed.ncbi.nlm.nih.gov/29571322
https://pubmed.ncbi.nlm.nih.gov/29571322
Autor:
Jason D. Tucker, Qilong Lu, Lauren E. Bollinger, Bo Wu, Sapana N. Shah, Peijuan Lu, Mingxing Wang
Publikováno v:
Polymers, Vol 9, Iss 5, p 177 (2017)
Polymers; Volume 9; Issue 5; Pages: 177
Polymers
Polymers; Volume 9; Issue 5; Pages: 177
Polymers
A series of amphiphilic peptides modified PMO (Pt-PMO) were prepared, and their antisense effect and toxicity were evaluated both in vitro and in mdx mice. The results showed that the exon-skipping performance of Pt-PMO are relative to the structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df9670a9c2fab67e1eceb26a756453a
http://www.mdpi.com/2073-4360/9/5/177
http://www.mdpi.com/2073-4360/9/5/177
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated for the delivery of antisense oligonuclotides (AOs), 2′-O-methyl phosphorothioate RNA (2′-OMePS) and phosphorodiamidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1b09b67fd053cace47fd5d9943d44d
Autor:
Taylor M. Luckie, Yubo Sun, Bo Wu, Lauren E. Bollinger, Amy Harper, Stephanie M. Richardson, Kyle Madden, Sapana N. Shah, Michael Cox, Peijuan Lu, Qi Long Lu, Anthony Blaeser, Susan Sparks
Publikováno v:
The American journal of pathology. 186(6)
Fukutin-related protein-muscular dystrophy is characterized by defects in glycosylation of α-dystroglycan with variable clinical phenotypes, most commonly as limb-girdle muscular dystrophy 2I. There is no effective therapy available. Glucocorticoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80003ee13e952da7196c3e49b77f8ee2
https://pubmed.ncbi.nlm.nih.gov/27109613
https://pubmed.ncbi.nlm.nih.gov/27109613
Publikováno v:
Molecular Therapy. 23:S60
Duchenne muscular dystrophy (DMD) results from dystrophin gene mutations, causing shift of the reading frame and preventing production of a functional protein. Most DMD mutations occur in the parts of the gene that are not critical for its function,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ee085c53a5d46e39485cb5dc94f5d2
https://doi.org/10.1016/s1525-0016(16)33753-4
https://doi.org/10.1016/s1525-0016(16)33753-4
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 5, Iss C (2016)
A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated for the delivery of antisense oligonuclotides (AOs), 2′-O-methyl phosphorothioate RNA (2′-OMePS) and phosphorodiamidat
Externí odkaz:
https://doaj.org/article/0afa6d8e93e64ed294e22db7aa349526