Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lauren E Williamson"'
Autor:
Clara T Schoeder, Pavlo Gilchuk, Amandeep K Sangha, Kaitlyn V Ledwitch, Delphine C Malherbe, Xuan Zhang, Elad Binshtein, Lauren E Williamson, Cristina E Martina, Jinhui Dong, Erica Armstrong, Rachel Sutton, Rachel Nargi, Jessica Rodriguez, Natalia Kuzmina, Brooke Fiala, Neil P King, Alexander Bukreyev, James E Crowe, Jens Meiler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010518 (2022)
The three human pathogenic ebolaviruses: Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) virus, cause severe disease with high fatality rates. Epitopes of ebolavirus glycoprotein (GP) recognized by antibodies with binding breadth for all three ebol
Externí odkaz:
https://doaj.org/article/83108648321c484bbf22f4df7b598b39
Autor:
Philipp A. Ilinykh, Kai Huang, Bronwyn M. Gunn, Natalia A. Kuzmina, Kritika Kedarinath, Eduardo Jurado-Cobena, Fuchun Zhou, Chandru Subramani, Matthew A. Hyde, Jalene V. Velazquez, Lauren E. Williamson, Pavlo Gilchuk, Robert H. Carnahan, Galit Alter, James E. Crowe, Alexander Bukreyev
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Antibodies to Ebola virus glycoprotein (EBOV GP) represent an important correlate of the vaccine efficiency and infection survival. Both neutralization and some of the Fc-mediated effects are known to contribute the protection conferred by a
Externí odkaz:
https://doaj.org/article/446ca9702148453eb38e081a5253376d
Autor:
Philipp A. Ilinykh, Kai Huang, Bronwyn M. Gunn, Natalia A. Kuzmina, Kritika Kedarinath, Eduardo Jurado-Cobena, Fuchun Zhou, Chandru Subramani, Matthew A. Hyde, Jalene V. Velazquez, Lauren E. Williamson, Pavlo Gilchuk, Robert H. Carnahan, Galit Alter, James E. Crowe, Alexander Bukreyev
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/363dea2b3f8140e3a227009c6ff258aa
Autor:
Charles D. Murin, Pavlo Gilchuk, Philipp A. Ilinykh, Kai Huang, Natalia Kuzmina, Xiaoli Shen, Jessica F. Bruhn, Aubrey L. Bryan, Edgar Davidson, Benjamin J. Doranz, Lauren E. Williamson, Jeffrey Copps, Tanwee Alkutkar, Andrew I. Flyak, Alexander Bukreyev, James E. Crowe, Jr., Andrew B. Ward
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108984- (2021)
Summary: Antibodies that target the glycan cap epitope on the ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization
Externí odkaz:
https://doaj.org/article/165fbb29f604470fb6b0a404b517d2da
Autor:
Lauren E. Williamson, Abhishek Bandyopadhyay, Kevin Bailey, Devika Sirohi, Thomas Klose, Justin G. Julander, Richard J. Kuhn, James E. Crowe
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Selection and development of monoclonal antibody (mAb) therapeutics against pathogenic viruses depends on certain functional characteristics. Neutralization potency, or the half-maximal inhibitory concentration (IC 50 ) values, is an important charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa3f16d75576972b8a304e684e54b8b7
https://doi.org/10.1073/pnas.2213690120
https://doi.org/10.1073/pnas.2213690120
Autor:
Natasha M. Kafai, Lauren E. Williamson, Elad Binshtein, Soila Sukupolvi-Petty, Christina L. Gardner, Jaclyn Liu, Samantha Mackin, Arthur S. Kim, Nurgun Kose, Robert H. Carnahan, Ana Jung, Lindsay Droit, Douglas S. Reed, Scott A. Handley, William B. Klimstra, James E. Crowe, Michael S. Diamond
Publikováno v:
The Journal of experimental medicine. 219(4)
Venezuelan equine encephalitis virus (VEEV) remains a risk for epidemic emergence or use as an aerosolized bioweapon. To develop possible countermeasures, we isolated VEEV-specific neutralizing monoclonal antibodies (mAbs) from mice and a human immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::854c83bc12f0c3a171f4b2b0edbdea40
https://pubmed.ncbi.nlm.nih.gov/35297953
https://pubmed.ncbi.nlm.nih.gov/35297953
Autor:
Tatianna Travieso, Priyamvada Acharya, Stephanie N. Langel, Sallie R. Permar, Katayoun Mansouri, Maria Blasi, Jerry Chang, Victoria Stalls, James E. Crowe, Lauren E. Williamson, Christoph P. Hornik, Huali Wu, Helen S. Webster, Claire Otero, Justin Steppe, Robert Edward, Harry B. Greenberg
SUMMARYBreast milk secretory IgA antibodies provide a first line of defense against enteric infections. Despite this and an effective vaccine, human rotaviruses (RVs) remain the leading cause of severe infectious diarrhea in children in low- and midd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d9e692acbccdc2a8078c1442bede79
https://doi.org/10.1101/2021.09.21.461116
https://doi.org/10.1101/2021.09.21.461116
Autor:
Philipp A. Ilinykh, James E. Crowe, Xiaoli Shen, Alexander Bukreyev, Andrew I. Flyak, Pavlo Gilchuk, Charles D. Murin, Jessica F. Bruhn, Lauren E. Williamson, Aubrey L. Bryan, Jeffrey Copps, Andrew B. Ward, Tanwee Alkutkar, Natalia Kuzmina, Benjamin J. Doranz, Edgar Davidson, Kai Huang
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108984-(2021)
Cell reports
Cell reports
SUMMARY Antibodies that target the glycan cap epitope on the ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4aad3cf89c598ab3f5717c47dbd873
http://www.sciencedirect.com/science/article/pii/S2211124721002989
http://www.sciencedirect.com/science/article/pii/S2211124721002989
Autor:
Philipp A. Ilinykh, James E. Crowe, Charles D. Murin, Jessica F. Bruhn, Alexander Bukreyev, Andrew I. Flyak, Kai Huang, Aubrey L. Bryan, Tanwee Alkutkar, Pavlo Gilchuk, Benjamin J. Doranz, Lauren E. Williamson, Natalia Kuzmina, Jeffrey Copps, Andrew B. Ward, Edgar Davidson, Xiaoli Shen
SummaryAntibodies that target the glycan cap epitope on ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization is not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::156c3eee774d011cbecc7ad64f875616
https://doi.org/10.1101/2020.10.14.340026
https://doi.org/10.1101/2020.10.14.340026
Autor:
Rachel E. Sutton, Rachel S. Nargi, Robert H. Carnahan, William B. Klimstra, Lauren E. Williamson, Elad Binshtein, Erica Armstrong, Theron Gilliland, Lauren M. Walker, Arthur S. Kim, James E. Crowe, Clarissa L Durie, Michael S. Diamond, Nurgun Kose, Pramod Kumar Yadav, Julie M. Fox, Melanie D. Ohi, Robin G. Bombardi
Publikováno v:
Cell
Eastern equine encephalitis virus (EEEV) is one of the most virulent viruses endemic to North America. No licensed vaccines or antiviral therapeutics are available to combat this infection, which has recently shown an increase in human cases. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cdf9725e44b8e263a6a9da6a70f084
https://pubmed.ncbi.nlm.nih.gov/33301709
https://pubmed.ncbi.nlm.nih.gov/33301709