Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Lauren E, Schwartz"'
Autor:
Kai Doberstein, Rebecca Spivak, Hunter D. Reavis, Jagmohan Hooda, Yi Feng, Paul T. Kroeger, Sarah Stuckelberger, Gordon B. Mills, Kyle M. Devins, Lauren E. Schwartz, Marcin P. Iwanicki, Mina Fogel, Peter Altevogt, Ronny Drapkin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
L1CAM is implicated as an important factor that enables early fallopian tube cancer precursors to seed the ovary by promoting cell survival through extracellular matrix signaling, thereby facilitating ovarian cancer growth.
Externí odkaz:
https://doaj.org/article/72d15a5115e24cf6806f17c0c2a2f6ba
Autor:
Adam J. Ferrari, Priyanka Rawat, Hannah S. Rendulich, Akshaya V. Annapragada, Yasuto Kinose, Xiaoming Zhang, Kyle Devins, Anna Budina, Robert B. Scharpf, Marilyn A. Mitchell, Janos L. Tanyi, Mark A. Morgan, Lauren E. Schwartz, T. Rinda Soong, Victor E. Velculescu, Ronny Drapkin
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Epigenetic aberrations, including posttranslational modifications of core histones, are major contributors to cancer. Here, we define the status of histone H2B monoubiquitylation (H2Bub1) in clear cell ovarian carcinoma (CCOC), low-grade serous carci
Externí odkaz:
https://doaj.org/article/5bf00bf256644fc89eedbd7ed9a32a9c
Autor:
Andrew R. Barsky, Ryan D. Kraus, Ruben Carmona, Patricia M. G. Santos, Carrie Li, Lauren E. Schwartz, Leslie K. Ballas, Neha Vapiwala
Publikováno v:
Cancer Medicine, Vol 9, Iss 10, Pp 3383-3389 (2020)
Abstract Background The significance of perineural invasion (PNI) in prostate cancer (PC) is unclear. A recent report of patients with pT2N0R0 PC found that PNI at prostatectomy was independently associated with higher Gleason score and more diffuse
Externí odkaz:
https://doaj.org/article/e590003f9d8049f69b73a0201f60ff90
Autor:
Haineng Xu, Erin George, Yasuto Kinose, Hyoung Kim, Jennifer B. Shah, Jasmine D. Peake, Benjamin Ferman, Sergey Medvedev, Thomas Murtha, Carter J. Barger, Kyle M. Devins, Kurt D’Andrea, Bradley Wubbenhorst, Lauren E. Schwartz, Wei-Ting Hwang, Gordon B. Mills, Katherine L. Nathanson, Adam R. Karpf, Ronny Drapkin, Eric J. Brown, Fiona Simpkins
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 9, Pp 100394- (2021)
Summary: CCNE1-amplified ovarian cancers (OVCAs) and endometrial cancers (EMCAs) are associated with platinum resistance and poor survival, representing a clinically unmet need. We hypothesized that dysregulated cell-cycle progression promoted by CCN
Externí odkaz:
https://doaj.org/article/317f0b4f67b94645ac9dda7eac42892d
Autor:
Jeffrey L. Barr, Allison Kruse, Anthony C. Restaino, Natalia Tulina, Sarah Stuckelberger, Samuel J. Vermeer, Caitlin S. Williamson, Daniel W. Vermeer, Marianna Madeo, Jillian Stamp, Maria Bell, Mark Morgan, Ju-Yoon Yoon, Marilyn A. Mitchell, Anna Budina, Dalia K. Omran, Lauren E. Schwartz, Ronny Drapkin, Paola D. Vermeer
Publikováno v:
Cells, Vol 10, Iss 12, p 3491 (2021)
Dense tumor innervation is associated with enhanced cancer progression and poor prognosis. We observed innervation in breast, prostate, pancreatic, lung, liver, ovarian, and colon cancers. Defining innervation in high-grade serous ovarian carcinoma (
Externí odkaz:
https://doaj.org/article/a0bd628c24b74ace80bfaa45a3eb3ebe
Autor:
Sara E Wobker, Paula S Ginter, Carlos Parra-Herran, Lauren E Schwartz, Garrett S Booth, Valerie A Fitzhugh, Julie K Silver, Francesca Khani
Publikováno v:
American Journal of Clinical Pathology. 158:499-505
Objectives Recognition awards build physician reputation and facilitate career advancement. We hypothesize women physicians are underrepresented as award recipients by pathology medical societies compared with representation in the specialty. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4b9d80139c67b0b3780de29a4d8882c
https://doi.org/10.1093/ajcp/aqac076
https://doi.org/10.1093/ajcp/aqac076
Autor:
Jacquelyn Powers, Daniel J. Lee, Kara N. Maxwell, Casey Morrison, Rachel L. Kember, Vivek Narayan, Abigail Doucette, Scott M. Damrauer, James Ding, Gregory Kelly, Heena Desai, Ryan Hausler, Renae Judy, Susan M. Domchek, Emily Feld, Lauren E. Schwartz, Peter Gabriel, Anh N Le, Daniel J. Rader, JoEllen Weaver
Publikováno v:
European Urology. 81:559-567
Background Identification of germline mutations in DNA repair genes has significant implications for the personalized treatment of individuals with prostate cancer (PrCa). Objective To determine DNA repair genes associated with localized PrCa in a di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a97b296938ff846ba700a2ebe13aeb
https://doi.org/10.1016/j.eururo.2021.09.029
https://doi.org/10.1016/j.eururo.2021.09.029
Autor:
Anthony C. Restaino, Austin Walz, Samuel J. Vermeer, Jeffrey Barr, Attila Kovács, Robin R. Fettig, Daniel W. Vermeer, Hunter Reavis, Caitlin S. Williamson, Christopher T. Lucido, Tuany Eichwald, Dalia K. Omran, Euihye Jung, Lauren E. Schwartz, Maria Bell, DesiRae M. Muirhead, Jody E. Hooper, William C. Spanos, Ronny Drapkin, Sebastien Talbot, Paola D. Vermeer
Publikováno v:
Science Advances. 9
The molecular and functional contributions of intratumoral nerves to disease remain largely unknown. We localized synaptic markers within tumors suggesting that these nerves form functional connections. Consistent with this, electrophysiological anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a23fb341ab0a2a7cb4dbade2811fd7d
https://doi.org/10.1126/sciadv.ade4443
https://doi.org/10.1126/sciadv.ade4443
Autor:
Irfan A. Asangani, Donita C. Brady, Matthew L. Freedman, Robert B. Den, Goutham Narla, Nallasivam Palanisamy, Daniel J. Lee, Lauren E. Schwartz, Javed Siddiqui, Mark M. Pomerantz, Sylvan C. Baca, Shannon Carskadon, Jessica M. Posimo, Erick Mitchell-Velasquez, Samuel Sander Effron, Priti Lal, Shweta Aras, Qu Deng, Ramakrishnan Natesan, Reyaz ur Rasool
Supplementary Figures S1-S12, Supplementary Table S1-3, supplementary methods and reference.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428b1ea3328b07aa415fc411cd6fc9e5
https://doi.org/10.1158/2159-8290.22535924
https://doi.org/10.1158/2159-8290.22535924
Autor:
Irfan A. Asangani, Donita C. Brady, Matthew L. Freedman, Robert B. Den, Goutham Narla, Nallasivam Palanisamy, Daniel J. Lee, Lauren E. Schwartz, Javed Siddiqui, Mark M. Pomerantz, Sylvan C. Baca, Shannon Carskadon, Jessica M. Posimo, Erick Mitchell-Velasquez, Samuel Sander Effron, Priti Lal, Shweta Aras, Qu Deng, Ramakrishnan Natesan, Reyaz ur Rasool
Metastatic castration-resistant prostate cancer (CRPC) is a fatal disease, primarily resulting from the transcriptional addiction driven by androgen receptor (AR). First-line CRPC treatments typically target AR signaling, but are rapidly bypassed, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fdbfe9bee4ee9a1af227f8fe379b406
https://doi.org/10.1158/2159-8290.c.6547985.v1
https://doi.org/10.1158/2159-8290.c.6547985.v1