Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lauren E, Peri"'
Autor:
Haeyeong Lee, Byoung H. Koh, Lauren E. Peri, Holly J. Woodward, Brian A. Perrino, Kenton M. Sanders, Sang Don Koh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα+) cells h
Externí odkaz:
https://doaj.org/article/2fec9f31909a46bb9ff04c8c8358e0b1
Autor:
Ken Lee, Sang O Park, Pil-Cho Choi, Seung-Bum Ryoo, Haeyeong Lee, Lauren E. Peri, Tong Zhou, Robert D. Corrigan, Andrew C. Yanez, Suk B. Moon, Brian A. Perrino, Kenton M. Sanders, Sang Don Koh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Volume accommodation occurs via a novel mechanism involving interstitial cells in detrusor muscles. The interstitial cells in the bladder are PDGFRα+, and they restrain the excitability of smooth muscle at low levels and prevents the develo
Externí odkaz:
https://doaj.org/article/2ffc5cafa1a74f33afd2860ded277ffe
Autor:
Mutafova-Yambolieva, Mafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Lauren E. Peri, Violeta N.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9964
The bladder urothelium releases ATP into the lamina propria (LP) during filling, which can activate P2X receptors on afferent neurons and trigger the micturition reflex. Effective ATP concentrations are largely dependent on metabolism by membrane-bou
Autor:
Sang Don Koh, Byoung H. Koh, Kenton M. Sanders, Lauren E. Peri, Haeyeong Lee, Brian A. Perrino, Holly J. Woodward
Cyclophosphamide (CYP)-induced cystitis is a rodent model that shares many features common to the cystitis occurring in patients, including detrusor overactivity (DO). Platelet-derived growth factor receptor alpha positive (PDGFRα+) cells regulate m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a039f22c7c2bea5ef69a2c00aefc5ea5
https://doi.org/10.21203/rs.3.rs-653727/v2
https://doi.org/10.21203/rs.3.rs-653727/v2
Autor:
Kenton M. Sanders, Matthew C. Shonnard, Lauren E. Peri, Sung Jin Hwang, Peter J. Blair, Yulia Bayguinov, Sean M. Ward
Publikováno v:
Diabetes
Patients with diabetes often develop gastrointestinal motor problems, including gastroparesis. Previous studies have suggested this gastric motor disorder was a consequence of an enteric neuropathy. Disruptions in interstitial cells of Cajal (ICC) ha
Autor:
Brian A. Perrino, Lauren E. Peri, Andrew Yanez, Suk Bae Moon, Sang Park, Seung-Bum Ryoo, Ken Lee, Sang Don Koh, Tong Zhou, Robert D. Corrigan, Kenton M. Sanders, Pil Choi, Haeyeong Lee
Volume accommodation occurs via a novel mechanism involving interstitial cells in detrusor muscles. The interstitial cells in the bladder are PDGFRα+ , and they restrain the excitability of smooth muscle at low levels and prevent the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15fd4aef2556cb78cffd3ab10ae5f93d
https://doi.org/10.21203/rs.3.rs-505840/v1
https://doi.org/10.21203/rs.3.rs-505840/v1
Autor:
Rachael Fortune-Grant, Haifeng Zheng, Yulia Bayguinov, Matthew C. Shonnard, Nathan Grainger, Jason R. Rock, Sean M. Ward, Sung Jin Hwang, Grant W. Hennig, Lauren E. Peri, David M. Pardo, Kenton M. Sanders, Sonali Deep Verma, Peter J. Blair, Robert S. Cook
Publikováno v:
J Physiol
KEY POINTS: Electrical pacemaking in gastrointestinal muscles is generated by specialized interstitial cells of Cajal that produce the patterns of contractions required for peristalsis and segmentation in the gut. The calcium‐activated chloride con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ef3c1002c85b53a4cdca515c7d64f4
https://europepmc.org/articles/PMC6487927/
https://europepmc.org/articles/PMC6487927/
Autor:
Benjamin E. Rembetski, Kenton M. Sanders, Lauren E. Peri, Salah A. Baker, Karolina E. Skowronek, Brian A. Perrino, Grant W. Hennig, Bernard T. Drumm
Publikováno v:
eNeuro
Interstitial cells of Cajal (ICC) regulate smooth muscle excitability and motility in the gastrointestinal (GI) tract. ICC in the deep muscular plexus (ICC-DMP) of the small intestine are aligned closely with varicosities of enteric motor neurons and
Autor:
Lauren E. Peri, Grant W. Hennig, Abigail S. Forrest, Amy A. Worth, Kenton M. Sanders, Sean M. Ward
Publikováno v:
Journal of Neurogastroenterology and Motility
Background/Aims Gastric peristalsis begins in the orad corpus and propagates to the pylorus. Directionality of peristalsis depends upon orderly generation and propagation of electrical slow waves and a frequency gradient between proximal and distal p
Autor:
Kenton M. Sanders, Robert D. Corrigan, Brian A. Perrino, Byoung H. Koh, Toby C. Chai, Haeyeong Lee, Lauren E. Peri, Hyun-Tai Lee, Sang Don Koh, Nikita E. George, Yeming Xie, Bhupal P. Bhetwal
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
During filling, urinary bladder volume increases dramatically with little change in pressure. This is accomplished by suppressing contractions of the detrusor muscle that lines the bladder wall. Mechanisms responsible for regulating detrusor contract