Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lauren D. Hatfield"'
Autor:
Justin A. Roby, Katharina Esser-Nobis, Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Johannes Schwerk, Amy Y. Lu, Frank W. Soveg, Emily A. Hemann, Lauren D. Hatfield, Brian C. Keller, Alexander Shapiro, Adriana Forero, Jennifer E. Stencel-Baerenwald, Ram Savan, Michael Gale
Publikováno v:
Cells, Vol 9, Iss 4, p 899 (2020)
Pathogenic flaviviruses antagonize host cell Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling downstream of interferons α/β. Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a wide range of cyt
Externí odkaz:
https://doaj.org/article/7543d266fff34f83bec7f5bdfb8814df
Publikováno v:
Proc Natl Acad Sci U S A
RIG-I, MDA5, and LGP2 comprise the RIG-I–like receptors (RLRs). RIG-I and MDA5 are essential pathogen recognition receptors sensing viral infections while LGP2 has been described as both RLR cofactor and negative regulator. After sensing and bindin
Autor:
Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Frank Soveg, Emily A. Hemann, Jennifer E. Stencel-Baerenwald, Michael Gale, Ram Savan, Lauren D. Hatfield, Adriana Forero, Justin A Roby, Amy Y. Lu, Brian C. Keller, Alexander Shapiro, Katharina Esser-Nobis, Johannes Schwerk
Publikováno v:
Cells, Vol 9, Iss 899, p 899 (2020)
Cells
Volume 9
Issue 4
Cells
Volume 9
Issue 4
Pathogenic flaviviruses antagonize host cell Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling downstream of interferons &alpha
/&beta
Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a
/&beta
Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a
RNA-binding protein isoforms ZAP-S and ZAP-L have distinct antiviral and immune resolution functions
Autor:
Michael Gale, Ram Savan, Alison M. Kell, Lomon So, Lauren D. Hatfield, Andrew P. Ryan, Matthew D. Daugherty, Snehal Ozarkar, Jennifer L. Hyde, Johannes Schwerk, Adriana Forero, Frank Soveg, Kerri R. Thomas, Justin A Roby
Publikováno v:
Nat Immunol
The initial response to viral infection is anticipatory, with host antiviral restriction factors and pathogen sensors constantly surveying the cell to rapidly mount an antiviral response through the synthesis and downstream activity of interferons. A