Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lauren C. Shaw"'
Autor:
Erin E. Grundy, Lauren C. Shaw, Loretta Wang, Abigail V. Lee, James Castro Argueta, Daniel J. Powell, Mario Ostrowski, R. Brad Jones, C. Russell Y. Cruz, Heather Gordish-Dressman, Nicole P. Chappell, Catherine M. Bollard, Katherine B. Chiappinelli
Publikováno v:
Mobile DNA, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transposable elements (TEs) are often expressed at higher levels in tumor cells than normal cells, implicating these genomic regions as an untapped pool of tumor-associated antigens. In ovarian cancer (OC), protein from the TE ERV-K is frequ
Externí odkaz:
https://doaj.org/article/ae60226c036b4df8a06919f4dc2441a1
Autor:
Alba Rodriguez-Garcia, Rachel C. Lynn, Mathilde Poussin, Monika A. Eiva, Lauren C. Shaw, Roddy S. O’Connor, Nicholas G. Minutolo, Victoria Casado-Medrano, Gonzalo Lopez, Takami Matsuyama, Daniel J. Powell
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Several strategies have been attempted to target immune suppressive populations in the tumor microenvironment. Here the authors show that folate receptor β-targeted CAR-T cells eliminate immunosuppressive tumor associated macrophages, promoting endo
Externí odkaz:
https://doaj.org/article/ccc6ff85f88e4afdb0a9c7be290f2a3b
Autor:
Lauren C. Shaw, Mathilde Poussin, Alba Rodriguez-Garcia, Joshua Eggold, Nicholas G. Minutolo, Jie Wang, Alain H. Rook, Stephen J. Schuster, Daniel J. Powell
Publikováno v:
Blood Advances. 7:1885-1898
Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of lymphoid malignancies associated with poor prognosis due to ineffective treatment options and high rates of relapse. The success of chimeric antigen receptor T-cell (CART) therapy for c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51107c32bde30672ad0417d7768c88db
https://doi.org/10.1182/bloodadvances.2022008798
https://doi.org/10.1182/bloodadvances.2022008798
Autor:
Daniel J. Powell, Roddy S. O’Connor, Nicholas G. Minutolo, Rachel C. Lynn, Lauren C. Shaw, Victoria Casado-Medrano, Mathilde Poussin, Takami Matsuyama, Alba Rodriguez-Garcia, Monika A. Eiva, Gonzalo Lopez
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The immunosuppressive tumor microenvironment (TME) represents a major barrier for effective immunotherapy. Tumor-associated macrophages (TAMs) are highly heterogeneous and plastic cell components of the TME which can either promote tumor progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4117b762b885fc2514214a6bf08d4eb5
https://pubmed.ncbi.nlm.nih.gov/33563975
https://pubmed.ncbi.nlm.nih.gov/33563975
Autor:
Lauren C. Shaw, Anže Smole, Fabiana Zappala, Prannda Sharma, Andrew Tsourkas, Nicholas G. Minutolo, Erin E. Hollander, Daniel J. Powell, Daniel P. Brown, Alba Rodriguez-Garcia, Mathilde Poussin, James Z. Hui
Publikováno v:
J Am Chem Soc
Universal immune receptors represent a rapidly emerging form of adoptive T-cell therapy with the potential to overcome safety and antigen escape challenges faced by conventional chimeric antigen receptor (CAR) T-cell therapy. By decoupling antigen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6d9850d8e1e04002a88411c4045307
https://europepmc.org/articles/PMC7306176/
https://europepmc.org/articles/PMC7306176/
