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pro vyhledávání: '"Lauren C. Cutmore"'
Autor:
Christina Amatya, Katherine A. Weissler, Vicki Fellowes, Norris Lam, Lauren C. Cutmore, Danielle A. Natrakul, Steven L. Highfill, James N. Kochenderfer
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101212- (2024)
T cells expressing anti-CD19 chimeric antigen receptors (CARs) have activity against chronic lymphocytic leukemia (CLL), but complete response rates range from 18% to 29%, so improvement is needed. Peripheral blood mononuclear cells (PBMCs) of CLL pa
Externí odkaz:
https://doaj.org/article/02693419e64d4267a885aa3aa7ba3a05
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The integrin αvβ6 is expressed at low levels in most normal healthy tissue but is very often upregulated in a disease context including cancer and fibrosis. Integrins use endocytosis and trafficking as a means of regulating their surface expression
Externí odkaz:
https://doaj.org/article/48f84d55c33c431fb2bb8f0b7e92b5fb