Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lauren C Tantalo"'
Autor:
Emily Romeis, Nicole A P Lieberman, Barbara Molini, Lauren C Tantalo, Benjamin Chung, Quynh Phung, Carlos Avendaño, Anastassia Vorobieva, Alexander L Greninger, Lorenzo Giacani
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011259 (2023)
BackgroundThe TprK protein of the syphilis agent, Treponema pallidum subsp. pallidum (T. pallidum), undergoes antigenic variation in seven discrete variable (V) regions via non-reciprocal segmental gene conversion. These recombination events transfer
Externí odkaz:
https://doaj.org/article/3637a32b0e5d45cab49823cc0c655e9f
Autor:
Arielle P Davis, Clare L Maxwell, Haley Mendoza, Abby Crooks, Shelia B Dunaway, Sher Storey, Claire Stevens, Lauren C Tantalo, Sharon K Sahi, Kevin R Robertson, Christina M Marra
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254518 (2021)
BackgroundIndividuals with previous syphilis may experience cognitive impairment. The goal of this study was to determine if those at high risk for laboratory-defined neurosyphilis are cognitively impaired, and whether treatment based on cerebrospina
Externí odkaz:
https://doaj.org/article/17a2315d4e974a79b2938855e07e948a
Autor:
Amin Addetia, Lauren C Tantalo, Michelle J Lin, Hong Xie, Meei-Li Huang, Christina M Marra, Alexander L Greninger
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 4, p e0007921 (2020)
Developing a vaccine against Treponema pallidum subspecies pallidum, the causative agent of syphilis, remains a public health priority. Syphilis vaccine design efforts have been complicated by lack of an in vitro T. pallidum culture system, prolific
Externí odkaz:
https://doaj.org/article/6340687d2c1346d2be1692ee4facef55
Publikováno v:
Sexually Transmitted Diseases. 50:180-183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16dd9ff3f98daee876d4929820feaa9f
https://doi.org/10.1097/olq.0000000000001739
https://doi.org/10.1097/olq.0000000000001739
Publikováno v:
Sexually Transmitted Diseases. 48:670-674
BACKGROUND At least 3 syphilis typing systems are proposed. Recent work suggests that multilocus sequence typing (MLST) may be superior to enhanced Centers for Disease Control and Prevention typing (ECDCT) by yielding a higher discriminatory power. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7802da24a8076c8c3b6dd1c9da44ba
https://doi.org/10.1097/olq.0000000000001378
https://doi.org/10.1097/olq.0000000000001378
Publikováno v:
Sexually transmitted diseases. 50(1)
Lumbar puncture is recommended for individuals with syphilis who have neurological symptoms; however, symptoms have poor sensitivity for predicting symptomatic neurosyphilis. Neurofilament light chain (NfL) is a marker for neuroaxonal injury; cerebro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fe40727e8a5172ae89638f25d076dc6
https://pubmed.ncbi.nlm.nih.gov/36194828
https://pubmed.ncbi.nlm.nih.gov/36194828
Autor:
Zachary S. Orban, Hemil Gonzalez, Ethan M. Ritz, Gregory Huhn, Lauren C. Tantalo, Igor J. Koralnik, Christina M. Marra
Publikováno v:
Sex Transm Dis
Background The diagnosis of neurosyphilis relies on cerebrospinal fluid (CSF) abnormalities (pleocytosis, elevated protein) and CSF-Venereal Disease Research Laboratory (VDRL) test. In resource-limited settings, the CSF-VDRL test may not be widely av
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0354c01505b9169f14722956bcbda567
https://doi.org/10.1097/olq.0000000000001308
https://doi.org/10.1097/olq.0000000000001308
Publikováno v:
Sex Transm Dis
BACKGROUND Syphilis diagnosis relies on serological tests, which may be falsely nonreactive or may be reactive but not reflect current syphilis. METHODS Polymerase chain reaction for detection of T. pallidum DNA was performed on 123 oropharyngeal swa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8daff5648514f9ee21db474d173395
https://europepmc.org/articles/PMC8595773/
https://europepmc.org/articles/PMC8595773/
Autor:
Quynh Phung, Lorenzo Giacani, Nicole A P Lieberman, Alexander L. Greninger, Lauren C. Tantalo, Emily Romeis
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009612 (2021)
PLoS Pathogens
PLoS Pathogens
Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful. The lack of genetic engineering tools has severely limited understanding of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295afb6cd69da4c11e2c69b891d1276c
https://doaj.org/article/2416de458b6342998c140c10f7ea5636
https://doaj.org/article/2416de458b6342998c140c10f7ea5636
Autor:
M Vall Mayans, Lauren C. Tantalo, C Nieto, Llorenç Quintó, Oriol Mitjà, M Ubals Cazorla, Lorenzo Giacani, Clara Pérez-Mañá
Publikováno v:
Poster presentations.
Background The shortage in the supply of benzathine penicillin G (BPG) and other limitations associated with BPG use underscore the need for new therapeutic options for syphilis treatment. Until recently, Treponema pallidum (T. pallidum), the syphili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89da9a78f684e498ed4aec9ef391b38f
https://doi.org/10.1136/sextrans-2021-sti.427
https://doi.org/10.1136/sextrans-2021-sti.427