Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lauren C Morehead"'
Autor:
Ana C Azevedo‐Pouly, Lauren E Appell, Lyle Burdine, Lora J Rogers, Lauren C Morehead, Daniel Fil, Melanie Barker, Randall R Rainwater, Zachary J Waldrip, Brian Koss, Marie Schluterman Burdine
Publikováno v:
Immunology & Cell Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79f3bebb98418343c8788280692dc52c
https://doi.org/10.1111/imcb.12651
https://doi.org/10.1111/imcb.12651
Autor:
Lauren C. Morehead, Sarita Garg, Katherine F. Wallis, Eric R. Siegel, Alan J. Tackett, Isabelle R. Miousse
Dietary methionine restriction, defined as reduction of methionine intake by around 80%, reproducibly decreases tumor growth and synergizes with cancer therapies. Here, we combined dietary methionine restriction with immune checkpoint inhibitors in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::817cf36761985639dd6afb276a7a9bb3
https://doi.org/10.2139/ssrn.4329452
https://doi.org/10.2139/ssrn.4329452
Autor:
Jordan T. Bird, Stephanie D. Byrum, Katherine F. Wallis, Lauren C. Morehead, Isabelle R. Miousse
Publikováno v:
Environ Mol Mutagen
Restriction of the sulfur amino acids methionine and cysteine has recently been proposed as potential adjuvant therapy in cancer. While cysteine depletion has been associated with ferroptotic cell death, methionine depletion has not. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb66a59855927937c72f635e24104af
https://doi.org/10.1002/em.22428
https://doi.org/10.1002/em.22428
Autor:
Ana C. Azevedo-Pouly, Lauren E. Appell, Lyle Burdine, Lora J. Rogers, Lauren C. Morehead, Melanie Barker, Zachary J. Waldrip, Brian Koss, Marie Schluterman Burdine
Modulation of T cell activity is an effective strategy for the treatment of autoimmune diseases, immune-related disorders and cancer. This highlights a critical need for continued investigation of proteins that regulate T cell function. The kinase DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b276a6b6584ef610e3c0b85a583a864
https://doi.org/10.1101/2022.06.23.497236
https://doi.org/10.1101/2022.06.23.497236
Autor:
Jacob L. Edmondson, Megan R. Reed, Lauren C. Morehead, Billie Heflin, Brian Koss, Alan J. Tackett
Publikováno v:
Cancer Research. 83:LB041-LB041
Unleashing the immune anti-tumor response through immune checkpoint inhibitors (ICIs) is a promising strategy to combat many solid-tumor malignancies, including metastatic melanoma. When successful, the anti-tumor response is potent; however, around
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ce52f26b484bc83f218b272f54bbfab
https://doi.org/10.1158/1538-7445.am2023-lb041
https://doi.org/10.1158/1538-7445.am2023-lb041
Publikováno v:
Immunotherapy. 11:75-79
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9b974412e5d7fa1d82c50d1f169a84
https://doi.org/10.2217/imt-2018-0129
https://doi.org/10.2217/imt-2018-0129
Publikováno v:
Cancer Research. 82:6131-6131
The introduction of immunotherapy has drastically improved outcomes in cancer therapy, particularly in melanoma, the deadliest form of skin cancer. However, around half of melanoma tumors are initially resistant to treatment and a significant proport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d28b3a627c72e2f3980f9196d93d1e
https://doi.org/10.1158/1538-7445.am2022-6131
https://doi.org/10.1158/1538-7445.am2022-6131
Publikováno v:
Cancer Research. 81:1577-1577
Immune checkpoint inhibitors (ICIs) have revolutionized melanoma therapy. Still, the 5-year survival for advanced melanoma is only 50%. This leads to two questions: what makes some tumors less responsive to ICIs, and what can be done to increase resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::092dbc736a180be8fc0e21ff2432fdcf
https://doi.org/10.1158/1538-7445.am2021-1577
https://doi.org/10.1158/1538-7445.am2021-1577
Publikováno v:
Cancer Research. 80:A06-A06
Autophagy is a cellular recycling mechanism triggered by nutrient scarcity. Upregulation of autophagy is associated with lifespan extension, DNA repair, and improved cancer immune recognition. Cancer cells can also utilize this mechanism to cope with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31dbfa7bfeba451adc0b7d1e33f02ce3
https://doi.org/10.1158/1538-7445.mel2019-a06
https://doi.org/10.1158/1538-7445.mel2019-a06
Autor:
Martin J. Cannon, Lauren C. Morehead
Publikováno v:
Annals of Research Hospitals. 2:8-8
Since the discovery of dendritic cells (DC) as potent stimulators of immune responses by Zanvil Cohn and Ralph Steinman in the 1970s, the idea that DC could be used as adjuvants for activation of antitumor immunity steadily gained traction, culminati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a924199755739e1d77037cc3c77834d0
https://doi.org/10.21037/arh.2018.08.02
https://doi.org/10.21037/arh.2018.08.02